Fast Mohs IHC

Rapid, Reliable Fast Mohs IHC.

Residual tumor is a primary cause of recurrence following Mohs micrographic surgery. Frozen section Immunohistochemistry (IHC) enhances detection sensitivity beyond H&E, supporting greater confidence in the assessment of challenging cases.

Bio SB’s Fast Mohs IHC Staining System integrates user friendly instrumentation, optimized target detection, and a menu of clinically validated antibodies to deliver consistent, efficient staining in as little as 10 to 20 minutes. Bio SB Fast Mohs IHC is compatible with both manual and automated staining platforms for effective implementation in laboratories of varying size and workflow complexity.

Residual tumor is a primary cause of recurrence following Mohs micrographic surgery. Frozen section Immunohistochemistry (IHC) enhances detection sensitivity beyond H&E, supporting greater confidence in the assessment of challenging cases.

CK AE1 / AE3

Stained with Fast Mohs PolyDetector Plus HRP Greenon Frozen Melanoma Tissue

The TintoDetector Mini

Compact, cost-effective solution for implementing Fast Mohs IHC. Integrated incubation and dual-slide reagent well system enables staining of two slides per well for higher manual output.

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The TintoStainer Plus Mini

The TintoStainer Plus Mini fully automates Fast Mohs IHC, delivering consistent results with true walkaway workflow automation.

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Efficient Manual IHC for Mohs Labs

The Bio SB TintoDetector Mini is a compact manual staining system designed for Fast Mohs IHC in space-constrained laboratories. Its streamlined manual workflow supports consistent staining and high throughput without the complexity or cost of full automation.

Developed in conjunction with Bio SB’s TintoFast antibodies and PolyDetector & PolyDetector Plus Detection Systems, the TintoDetector Mini integrates seamlessly into Mohs laboratory workflows.

The Bio SB TintoDetector Mini is a compact manual staining system designed for Fast Mohs IHC in space-constrained laboratories. Its streamlined manual workflow supports consistent staining and high throughput without the complexity or cost of full automation.

Fast Mohs PolyDetector HRP Detection Systems

Fast Mohs PolyDetector HRP Detection is one-step non-biotin, Fab micropolymer detection system for MART-1 IHC staining on FFPE and frozen tissue sections.

The elimination of the immunoglobulin Fc region reduces non-specific binding and background staining. The result is consistent, high quality immunostaining across nuclear, cytoplasmic and membranous targets.

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Fast Mohs PolyDetector HRP Protocol

Bio SB’s MART-1 Fast Mohs PolyDetector HRP protocol can be completed in 10 minutes on frozen tissue sections using the TintoDetector Mini Staining System.

Fast Mohs PolyDetector Plus HRP Detection Systems

The Bio SB Mohs PolyDetector Plus is a highly sensitive two-step non-biotin, Fab micropolymer detection system for increased sensitivity and signal amplification on FFPE and frozen tissue sections.

Fast Mohs PolyDetector Plus Detection incorporates an additional linker component to increase signal strength while minimizing background staining. This supports clear, high quality immunostaining, including on more challenging nuclear markers.

Its enhanced sensitivity supports rapid staining protocols for all TintoFast antibodies.

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Fast Mohs PolyDetector Plus HRP Protocol

Bio SB’s Fast Mohs PolyDetector Plus HRP protocol can be completed in 20 minutes on frozen tissue sections using the TintoDetector Mini Staining System.

Antibodies for Fast Mohs IHC

Bio SB’s high-affinity monoclonal antibodies are optimized to support rapid, reliable Fast Mohs IHC.

TintoFast SOX-10 (BSB-62)

TintoFast Podoplanin (D2-40)

TintoFast Prame (RBT-PRAME)

TintoFast p40 (ZR8)

TintoFast p63 (4A4)

TintoFast NGFR (BSB-18)

TintoFast MiTF (C5/D5)

TintoFast Ki-67 (RM360)

TintoFast Melanoma Cocktail: HMB-45, Mart-1 and Tyrosinase (HMB-45, A103 & BSB-6)

TintoFast MART-1 (A103)

TintoFast EpCAM (Ber-EP4)

TintoFast EMA (E29)

TintoFast HMB-45 (HMB-45)

TintoFast CK7 (OV-TL 12/30)

TintoFast CK AE1 and AE3 (AE1/AE3)

TintoFast CK 5 and 6 (D5/16B4)

TintoFast CD31 (1A10)

TintoFast CD34 (QBEnd/10)

TintoFast Chromogranin A (LK2H10)

TintoFast Androgen Receptor (BSB-4)

TintoFast Adipophilin (BSB-91)

MART-1 stained with PolyDetector Plus DAB HRP Brown on Frozen Melanoma Tissue

PRAME stained with PolyDetector Plus HRP DAB Brown on Frozen Melanoma Tissue

SOX-10 stained with PolyDetector Plus HRP Green on Frozen Melanoma Tissue

Explore Our Resources

Bio SB offers practical training resources to help laboratories confidently implement Fast Mohs IHC. Explore our Fast Mohs IHC brochure and instructional videos or contact sales@biosb.com to schedule a consultation.

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