{"type":"root","children":[{"type":"paragraph","children":[{"type":"text","value":"Tyrosinase is a copper-containing enzyme present in plant and animal tissues. It catalyzes the oxidation of phenols (such as tyrosine) to produce melanin and other pigments. The gene for tyrosinase is regulated by the microphthalmia-associated transcription factor (MITF). A mutation in the tyrosinase gene can lead to impaired tyrosinase production resulting in Type I oculocutaneous albinism, a hereditary disease that affects 1 in 17,000 people in the U.S. Tyrosinase is primarily expressed in melanosomes, organelles within melanocytes, as well as melanocytic lesions."}]}]}