{"type":"root","children":[{"type":"paragraph","children":[{"type":"text","value":"Simian vacuolating virus 40 or Simian virus 40 (SV40), a polyomavirus that is found in both monkeys and humans. Like other polyomaviruses, SV40 is a DNA virus that has the potential to cause tumors, but most often persists as a latent infection. The SV40 genome is divided into early and late regions, with the early region coding for the large and small T-ags and the late region encoding the capsid proteins VP1, VP2, and VP3. T-ag forms complexes with several cellular proteins, including tumor suppressor proteins, which explains SV40’s oncogenic capacity."}]}]}