{"type":"root","children":[{"type":"paragraph","children":[{"type":"text","value":"Stathmin 1/oncoprotein 18, also known as STMN1, is a highly conserved 17 kDa protein. Stathmin performs an important function in regulating rapid microtubule remodeling of the cytoskeleton in response to the cell’s needs. Regulation of stathmin is cell cycle dependent and controlled by the cell’s protein kinases in response to specific cell signals. Stathmin can cause uncontrolled cell proliferation when mutated and not functioning properly. Overexpression of stathmin has been associated with tumor progression in endometrial carcinomas, ovarian cancer and oral squamous-cell carcinoma."}]}]}