{"type":"root","children":[{"type":"paragraph","children":[{"type":"text","value":"MART-1, also known as Melanoma Antigen Recognized by T-cells 1 or Melan-A, is a 18 kDa transmembrane protein involved in the maturation process of melanosome cells. MART-1 is essential for the synthesis and transport of melanin, the pigment responsible for skin coloration and protection against UV radiation. MART-1 expression is tightly regulated during melanocyte development and differentiation, with minimal or no expression in most other cell types. MART-1 expression has been detected in both melanocytes and melanocyte-derived tumors, including metastatic melanocytes in lymph nodes and distant organs."}]}]}