{"type":"root","children":[{"type":"paragraph","children":[{"type":"text","value":"Herpes simplex virus I and II are members of the Herpes virus family, Herpesviridae, which causes infections in humans. The double stranded DNA genome is contained within an icosahedral capsid embedded in a proteinaceous layer (tegument) and surrounded by a lipid envelope, derived from the nuclear membrane of the last host, which is decorated with virus-specific glycoprotein spikes. HSV I and II have antigenic differences in their envelope proteins and cause mucocutaneous infections. Herpes simplex virus I usually infects the non-genital mucosal surfaces, and Type II typically involves the genitalia. Either type may affect the skin or internal organs (typically brain, lung, liver, adrenal gland, or gastrointestinal tract) of immunocompromised individuals."}]}]}