{"type":"root","children":[{"type":"paragraph","children":[{"type":"text","value":"Herpes simplex virus I is a strain of the Herpes virus family, Herpesviridae, which causes infections in humans. The double stranded DNA genome is contained within an icosahedral capsid embedded in a proteinaceous layer (tegument) and surrounded by a lipid envelope, derived from the nuclear membrane of the last host, which is decorated with virus-specific glycoprotein spikes. Herpes simplex virus I causes a contagious disease, also known as cold sore, night fever, or fever blister. After an initial, or primary, infection, Herpes simplex virus I establishes latency, during which the virus is present in the cell bodies of nerves which innervate the area of original outbreak. Herpes symptoms may periodically recur in the form of outbreaks of herpetic sores near the site of original infection. Herpes simplex virus I usually infects the non-genital mucosal surfaces, and Type II typically involves the genitalia. Either type may affect the skin or internal organs (typically brain, lung, liver, adrenal gland, or gastrointestinal tract) of immunocompromised individuals."}]}]}