{"type":"root","children":[{"type":"paragraph","children":[{"type":"text","value":"Glucagon is a 29-amino acid polypeptide acting as an important hormone in carbohydrate metabolism. The hormone is synthesized and secreted from alpha cells of the islets of Langerhans, which are located in the endocrine portion of the pancreas. According to literature, abnormally-elevated levels of glucagon may be caused by pancreatic malignancies such as glucagonoma, symptoms of which include necrolytic migratory erythema, elevated amino acids and hyperglycemia."}]}]}