{"type":"root","children":[{"type":"paragraph","children":[{"type":"text","value":"Fascin is a 55 kDa protein, plays a key role in cell migration and cancer metastasis by bundling actin filaments into parallel, stable structures. Fascin-1 is the most common type and widely expressed in various tissues. Fascin-1 is present in specialized cells with extensive surfaces or migratory potential, such as neurons, glia, dendritic cells, macrophages, skeletal and smooth muscle, endothelial cells; but not in normal epithelial cells. Fascin is also expressed in Reed Sternberg cells in Hodgkin’s lymphoma."}]}]}