Summary & Explanation
{"type":"root","children":[{"type":"paragraph","children":[{"type":"text","value":"CD30 is a transmembrane cytokine receptor belonging to the tumor necrosis factor receptor superfamily. Mature CD30 has a molecular mass of 120 kDa and is derived from a 90 kDa precursor protein.CD30 is found in activated B lymphocytes, plasma cells, T lymphocytes, NK cells, monocytes, large lymphoid cells in lymph nodes, tonsil, thymus, deciduas and endometrial cells with decidual change. CD30 is also expressed by Reed-Sternberg cells in Hodgkin’s disease, the majority of anaplastic large-cell lymphomas, and in embryonal carcinomas and seminomas according to literature."}]}]}
Presentation
Five slides of CD30 positive tissues, each mounted on Hydrophilic Plus Slides, provided in a plastic mailer.
Principle of Procedure
Control slides are Hydrophilic Plus Slides with formalin-fixed, paraffin-embedded (FFPE) tissue or cell sections mounted on them, serving as a tool to qualitatively verify the performance of immunohistochemical staining
