{"type":"root","children":[{"type":"paragraph","children":[{"type":"text","value":"CD20 is a transmembrane, non-glycosylated protein expressed on B-cell precursors and mature B-cells, but lost following differentiation into plasma cells. CD20 is not expressed in non-hematopoietic neoplasms, but is expressed in Reed-Sternberg cells predominant in Hodgkin’s disease."}]}]}