{"type":"root","children":[{"type":"paragraph","children":[{"type":"text","value":"Calretinin is a vitamin D-dependent calcium-binding protein involved in the signaling pathway of intracellular calcium, an important messenger in cellular proliferation and differentiation. It is expressed in the central and peripheral nervous system and in many normal and pathological tissues. According to literature, calretinin is expressed in mesothelioma, ameloblastomas, and adrenal-cortical neoplasms."}]}]}