{"type":"root","children":[{"type":"paragraph","children":[{"type":"text","value":"MUM1 (multiple myeloma oncogene-1) also known as interferon regulatory factor 4 (IRF4) is a 50 kDa protein and is a member of the interferon regulatory factor family of transcription factors. It is induced by antigen receptor mediated stimuli and plays an important role in cell proliferation, differentiation and survival. MUM1 is expressed in the nuclei and cytoplasm of plasma cells and a small percentage of germinal center (GC) B-cells committed to plasmacytic or memory cell differentiation in the “light zone”."}]}]}