Summary & Explanation
{"type":"root","children":[{"type":"paragraph","children":[{"type":"text","value":"Neurofilaments are the Type IV family of intermediate filaments that are found in high concentrations along the axons of vertebrate neurons. Neurofilament antibody stains an antigen localized in a number of neural, neuroendocrine and endocrine tumors. Neuromas, Ganglioneuromas, Gangliogliomas, Ganglioneuroblastomas and Neuroblastomas stain positively for neurofilament. Neurofilaments are also present in Paragangliomas and Adrenal and Extra-Adrenal Pheochromocytomas. Carcinoids, Neuroendocrine Carcinomas of the Skin, and Oat Cell Carcinomas of the Lung also express neurofilament."}]}]}
Antibody Type
Mouse Monoclonal
Clone
2F11
Isotype
IgG1/K
Localization
Cytoplasmic
Dilution
1:250-1:1000
Species Reactivity
Human, Canine, Rat, Mouse, Horse
Immunogen
Purified human neurofilament preparation.
