{"type":"root","children":[{"type":"paragraph","children":[{"type":"text","value":"Luteinizing hormone (LH) is a hormone synthesized and secreted by gonadotropes in the anterior lobe of the pituitary gland. In concert with the other pituitary gonadotropin follicle-stimulating hormone (FSH), it is necessary for proper reproductive function. In the female, an acute rise of LH levels triggers ovulation. In the male, where LH has also been called Interstitial Cell-Stimulating Hormone (ICSH), it stimulates Leydig cell production of testosterone."}]},{"type":"paragraph","children":[{"type":"text","value":"LH is a useful marker in classification of Pituitary Tumors and the study of pituitary disease. LH antibody reacts with LH-producing cells (gonadotrophs)."}]}]}