Summary & Explanation
{"type":"root","children":[{"type":"paragraph","children":[{"type":"text","value":"CA-125 reacts with malignant ovarian epithelial cells. CA-125 also reacts with antigens in Seminal Vesicle Carcinoma and Anaplastic Lymphoma."}]},{"type":"paragraph","children":[{"type":"text","value":"In adult tissues, CA-125 is found in epithelial cells of Fallopian tube, endometrium and endocervix, pancreas, colon, gall bladder, stomach, kidney, apocrine sweat gland, and mammary gland. It is also found in mesothelial cell lining of pleura, pericardium and peritoneum. It is found in ovarian tumors of serous, endometrioid or clear-cell types and Adenocarcinomas of Mullerian type."}]}]}
Antibody Type
Mouse Monoclonal
Clone
OC125
Isotype
IgG1/K
Localization
Cytoplasmic, Membranous
Dilution
1:50-1:200
Species Reactivity
Human
Immunogen
Partially purified human mucin fraction from a pool of tissues from patients with epithelial ovarian cancer.
