Summary & Explanation
{"type":"root","children":[{"type":"paragraph","children":[{"type":"text","value":"Homeobox protein NKX6.1 (NKX6A or NKX6-1) is a member of the NKX family of transcription factors with a DNA binding domain. This protein plays a critical role in pancreatic β cell function and proliferation. NKX6.1 is expressed in the nervous system during development and plays a key role in motor neuron specification. NKX6.1 also functions as an epithelial-to-mesenchymal transition suppressor, thereby suppressing the metastatic behavior of cancer cells according to literature."}]}]}
Antibody Type
Rabbit Monoclonal
Clone
RBT-NKX6.1
Control
Pancreas, Tonsil, PNET Sarcoma, Thyroid
Isotype
IgG
Localization
Nuclear
Dilution
1:10-1:50
Species Reactivity
Human
Immunogen
Synthetic peptide corresponding to residues of the human NKX6.1 protein
