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IHC of NKX6.1 on FFPE Normal Pancreas tissue

NKX6.1 (RBT-NKX6.1)

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Product Information

Summary & Explanation

{"type":"root","children":[{"type":"paragraph","children":[{"type":"text","value":"Homeobox protein NKX6.1 (NKX6A or NKX6-1) is a member of the NKX family of transcription factors with a DNA binding domain. This protein plays a critical role in pancreatic β cell function and proliferation. NKX6.1 is expressed in the nervous system during development and plays a key role in motor neuron specification. NKX6.1 also functions as an epithelial-to-mesenchymal transition suppressor, thereby suppressing the metastatic behavior of cancer cells according to literature."}]}]}

Antibody Type

Rabbit Monoclonal

Clone

RBT-NKX6.1

Control

Pancreas, Tonsil, PNET Sarcoma, Thyroid

Isotype

IgG

Localization

Nuclear

Dilution

1:10-1:50

Species Reactivity

Human

Immunogen

Synthetic peptide corresponding to residues of the human NKX6.1 protein