{"type":"root","children":[{"type":"paragraph","children":[{"type":"text","value":"CD61 is a glycoprotein found on megakaryocytes (bone marrow cells), platelets and their precursors. CD61 antigen plays a role in platelet aggregation and also as a receptor for fibrinogen, fibronectin, von Willebrand factor and vitronectin."}]},{"type":"paragraph","children":[{"type":"text","value":"CD61 labels the IIIa subunit of the noncovalently-linked glycoprotein heterodimer IIb/IIIa complex present on human platelets and their precursors. This antibody is useful in identifying megakaryoblastic differentiation as seen in Megakaryoblastic Leukemia."}]}]}