Summary & Explanation
{"type":"root","children":[{"type":"paragraph","children":[{"type":"text","value":"Neurofilaments are the Type IV family of intermediate filaments that are found in high concentrations along the axons of vertebrate neurons. Neurofilament antibody identifies an antigen localized in a number of neural, neuroendocrine and endocrine tumors. Neuromas, Ganglioneuromas, Gangliogliomas, Ganglioneuroblastomas and Neuroblastomas stain positively for neurofilament. Neurofilaments are also present in Paragangliomas and Adrenal and Extra- Adrenal Pheochromocytomas. Carcinoids, Neuroendocrine Carcinomas of the Skin, and Oat Cell Carcinomas of the Lung also express neurofilament."}]}]}
Antibody Type
Rabbit Monoclonal
Clone
EP79
Isotype
IgG
Localization
Cytoplasmic
Dilution
1:100-1:500
Species Reactivity
Human
Immunogen
A synthetic peptide corresponding to residues in human Neurofilament M protein.
