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Summary & Explanation
{"type":"root","children":[{"type":"paragraph","children":[{"type":"text","value":"The 4-Core Mismatch Repair, MMR Cell Line Microarray (CLMA) is an unstained ready-to-use microscope slide consisting of four - 2 mm cores of knockout mutations of the individual Mistmatch Repair genes MLH1, MSH2, MSH6 and PMS2. These formalin-fixed, paraffin-embedded (FFPE) cell lines are assembled in array fashion to allow molecular pathology analysis and validation of reagents, or to be used as controls for immunohistochemistry."}]}]}
Materials and Presentation
Five slides of 4-Core MMR CLMA’s with four - 2 mm cores each, mounted on Hydrophilic Plus Slides, provided in a plastic mailer.
Principle of Procedure
Control slides are Hydrophilic Plus Slides with FFPE tissue or cell sections mounted on them, serving as a tool to qualitatively verify the performance of immunohistochemical staining procedures.
Each control slide contains tissue with known expression of the antigen targeted by the specific antibody. Positive staining on the control slide confirms the antibody’s functionality and the proper execution of the staining protocol.