Reliable Immunohistochemistry Results in Just 5-20 Minutes!
Quality Antibodies | Sensitive Detection | Less Time
The most common reason for recurrence of skin cancers after Mohs micrographic surgery is residual undetected tumor. Frozen tissue Immunohistochemistry (IHC) has demonstrated greater sensitivity than routine H&E stains, which are difficult to interpret. Bio SB has developed a highly sensitive non-biotin monovalent Fab micropolymer immunohistochemistry detection system for the fast detection of IVD antibodies for melanoma, BCC, SCC and other Mohs surgery related conditions. Our innovative IHC detection systems and high affinity monoclonal antibodies, have opened the doors for a faster and accurate immunohistochemistry applicable to Mohs surgery.
Overview & Features of the PolyDetector HRP System 5-10 Min IHC
Intended for the detection of MART-1, and Cytokeratins (CK5/6, CK AE1/AE3, CK7)
The Bio SB Mohs PolyDetector is a non-Biotin, Fab Micropolymer detection system that allows for the demonstration of antigens in FFPE tissues, Mohs cryostat sections, blood smears, cytosmears, and cell preparations. The Bio SB Mohs PolyDetector technology was developed with our proprietary Micropolymer backbone, conjugated to Anti-Mouse and Anti-Rabbit Fab fraction of IgG’s, plus high quality HRP. The elimination of the immunoglobulin Fc region reduces non-specific reactions and background. This ensures consistent and reproducible immunostaining for all types of nuclear, cytoplasmic and membranous antigens, in different types of tissues. The increased sensitivity of this system allows for rapid staining procedures without compromising the stain quality. The Bio SB Mohs PolyDetector HRP Detection System is recommended for easy to detect antigens like MART-1 and Cytokeratins.
- Non-Biotin, Fab Micropolymer HRP 1-Step immunohistochemistry detection technology.
- Fab Micropolymer detection technology allows forbetter cell penetration to deliver a highly specific and sensitive signal.
- Ready-to-use, high sensitivity system especially designed for immunohistochemistry of frozen tissues.
- Universal: detects mouse or rabbit antibodies.
- Developed as DAB HRP Brown and HRP Green detection kits, but can be used with the AEC HRP Red, HRP Blue and HRP Black substrate-chromogens.
- Designed to be used manually, or can be optimized to work with any open, automated system.
- For in vitro diagnostic use. All kits manufactured according to US FDA and ISO 13485 guidelines.
Fast Mohs PolyDetector HRP Protocol
Overview & Features of the PolyDetector Plus HRP System 20 Min IHC
Intended for the detection of MART-1, Cytokeratins (CK5/6, CK AE1/AE3, CK7) Androgen Receptor, CD31, epCAM, BerEP4, EMA, Ki-67, MiTF, p40, p63, Podoplanin, NGFR and SOX-10.
The Bio SB Mohs PolyDetector Plus is a highly sensitive non-Biotin, Fab Micropolymer detection system that allows for the demonstration of antigens in FFPE tissues, Mohs cryostat sections, blood smears, cytosmears, and cell preparations. The Bio SB Mohs PolyDetector Plus technology was developed with our proprietary Micropolymer backbone, conjugated to Anti-Link Fab fraction of IgG’s, plus high quality HRP. The elimination of the Anti-Link Fc region reduces non-specific reactions and background. The Mohs PolyDetector Plus kit incorporates an immunoglobulin link and a Fab micropolymer label. This multiple component Fab Micropolymer delivers a highly sensitive and more specific signal than the Mohs PolyDetector kit. The Bio SB Mohs PolyDetector Plus HRP Detection System is recommended for easy to detect antigens and more difficult to detect antigens like nuclear targets.
- Non-Biotin, 2-Step immunohistochemistry detection technology.
- Recommended for easy to detect antigens and more difficult to detect antigens like nuclear targets.
- Anti-mouse and rabbit Fab Micropolymer detection technology allows for better cell penetration to deliver a highly specific and sensitive signal.
- Ready-to-use, high sensitivity system especially designed for immunohistochemistry of frozen tissues.
- Developed as DAB HRP Brown and HRP Green detection kits, but can be used with the AEC HRP Red, HRP Blue and HRP Black substrate-chromogens.
- For in vitro diagnostic use. All kits manufactured according to US FDA and ISO 13485 guidelines.
Fast Mohs PolyDetector Plus HRP Protocol
Shop All Fast Mohs Immunohistochemistry Products:
BCC, SCC and Lymphoepithelioma-like Carcinoma Antibodies
TintoFast Androgen Receptor, RMab
TintoFast Cytokeratin 5/6, MMab
Dermatofibrosarcoma Protuberans (DFPS) Antibodies
Melanoma Antibodies
TintoFast Melanoma Cocktail: HMB-45, MART-1 & Tyrosinase, MMab
Neuroendocrine Tumor Antibodies
TintoFast Chromogranin A, MMab
Paget’s Disease Antibodies
Primary Cutaneous Adnexal Neoplasm Antibodies
Tintofast Androgen Receptor, MMab