B-Cell Lymphomas Return to Top | |||||||||||||||||||||||||
| Lymphomas | CD45 | CD20 | CD79a | bcl-2 | bcl-6 | CD10 | CD23 | Cyclin D1 | PAX-5 | BOB.1 | Oct-2 | PU.1 | p27/Kip1 | IgD | MUM1 | T-beta | TRAcP | Annexin A1 | CD5 | CD43 | CD3 | ZAP-70 | CD25 | FOXP1 | TCL1 |
| Follicular | + | + | + | + | + | + | – | – | + | + | + | + | + | + | – | – | – | – | – | – | – | – | – | + | |
| CLL/SLL | + | + | + | + | – | – | + | – | + | + | + | + | + | + | + | + | – | – | + | + | – | +/- | + | ||
| Mantle Cell | + | + | + | + | – | – | – | + | + | + | + | + | + | + | – | – | – | – | + | + | – | – | – | -/+ | + |
| Marginal Zone BCL | + | + | + | + | – | – | – | – | + | + | + | + | + | -/+ | + | + | +/- | – | – | – | – | – | – | ||
| Lymphoplasmacytic | + | + | + | + | – | – | – | – | + | + | + | – | + | + | – | – | – | – | – | – | – | + | |||
| Diffuse Large Cell Lymphoma | + | + | + | + | + | – | – | – | + | + | + | + | – | – | + | – | – | – | – | – | – | + | -/+ | ||
| Burkitt Lymphoma | + | + | + | – | + | + | – | – | + | – | – | – | – | – | – | + | – | – | + | ||||||
| Hairy Cell Leukemia | + | + | + | + | – | – | – | – | + | – | – | + | + | + | – | – | – | + | |||||||
T-Cell Lymphomas Return to Top | |||||||||||||||
| Lymphomas | CD45 | CD2 | CD3 | CD4 | CD5 | CD7 | CD8 | CD25 | CD45RO | PD-1 | CD56 | CD57 | Perforin | Granzyme_B | TCL1 |
| Angioblastic | + | + | + | + | + | + | +/- | + | + | + | |||||
| Lymphoblastic | + | +/- | + | +/- | + | + | +/- | + | + | – | – | ||||
| Subcutaneous Panniculitic | + | + | + | – | + | + | +/- | – | + | – | – | + | + | ||
| Lennert’s | + | + | + | – | + | – | + | + | – | – | |||||
| NK-Type | + | + | + | – | – | + | – | + | + | – | +/- | +/- | – | + | + |
| Cutaneous | + | + | + | + | – | + | – | – | – | – | + | + | – | ||
| Peripheral | + | + | + | + | + | – | – | + | + | – | – | – | – | – | – |
| Mycosis Fungoides | + | + | + | + | + | – | – | + | + | – | – | – | |||
Acute Myeloid Leukemia Return to Top | |||||||||||||||
| Leukemia | MPO | CD68 | Factor VIII | CD61A | Hemoglobin A | BOB.1 | Oct-2 | Glycophorin A | Spectrin | CD34 | CD43 | CD74 | CD45 | Lysozyme | CD138 |
| Acute Myeloid, M0 | – | – | – | – | – | – | – | – | – | + | + | + | + | + | + |
| Myeloblast, M1&2 | + | + | – | – | – | – | – | – | + | + | + | + | + | ||
| Promyelocytic, M3 | + | + | – | – | – | + | + | – | + | – | |||||
| Myelomonocytic, M4 | + | + | – | – | – | – | + | – | – | + | + | + | + | + | |
| Monoblastic, M5 | + | + | – | – | – | – | + | – | – | – | + | + | + | + | |
| Acute Myeloid, M6 | + | – | – | – | – | – | + | + | – | – | + | ||||
| Megakaryocytic, M7 | – | – | + | + | – | +/- | – | – | – | ||||||
| Megakaryoblast | + | + | + | + | – | ||||||||||
Lymphoblastic Lymphomas: BCL vs TCL Return to Top | ||||||||||
| Lymphomas | TDT | CD10 | PAX-5 | CD20 | CD19 | CD3 | CD5 | CD7 | CD117 | CD74 |
| Lymphoblastic BCL | + | +/- | + | +/- | + | – | – | – | – | + |
| Lymphoblastic TCL | + | + | – | – | – | + | +/- | + | – | – |
Plasma Cells Return to Top | |||||||||
| Lymphomas | CD138 | CD79a | EMA | MUM1 | CD56 | Cyclin D1 | CD43 | CD20 | CD19 |
| Plasma Cell Tumor | + | + | + | + | + | – | – | – | – |
Lymph Node Histiocytosis Return to Top | |||||||
| Lymphomas | CD68 | S-100 | CD1a | Lysozyme | CD21/CD35 | FDC | PD-1 |
| Reactive | + | – | – | + | – | – | – |
| Langerhans | + | + | + | + | – | – | – |
| Sinus Histiocytosis with | + | + | – | + | – | – | – |
| Massive Lymphadenopathy | |||||||
| Follicular Dendritic Cell Tumor | – | – | – | – | + | + | + |
| Dermatopathic Lymphadenitis | – | + | + | + | – | – | – |
Histiocytic Lesions Return to Top | ||||||||
| Lymphomas | CD45 | CD4 | CD68 | Lysozyme | CD163 | Factor XIIIa | CD20 | CD3 |
| Histiocytic Lesions | + | + | + | + | + | + | – | – |
Histiocytic Proliferation Return to Top | |||||||
| Lymphomas | S-100 | CD68 | Vimentin | Lysozyme | CD1a | Factor XIIIa | HAM56 |
| Juvenile Xanthogranuloma | – | + | + | + | – | + | + |
| Langerhans Cell Histiocytosis | + | + | + | + | + | – | + |
| Dermatobroma | – | + | + | – | – | + | + |
Immunoglobulin: Heavy and Light Chain Return to Top | ||||||
| Lymphomas | IgA | IgG | IgD | IgM | Kappa | Lambda |
| Secretory Meningioma | + | – | – | + | ||
| Microvillous Lymphoma | – | – | – | + | ||
| Cutaneous Lymphoma | – | – | – | – | ||
| Myeloma | + | + | +/- | – | + | + |
| Diffuse LBCL | – | + | – | + | + | + |
| Marginal Zone Lymphoma | – | – | -/+ | + | + | + |
| SLL/CLL | – | – | + | + | + | + |
B-Cell Maturation Return to Top | ||||
| Lymphomas | CD20 | CD79a | CD19 | |
| Pro-B | – | + | + | |
| Pre-B | – | + | + | |
| Late Pre-B | + | + | + | |
| Mantle B-cells | + | + | + | |
| Centroblastic | + | + | + | |
| Centrocytic | + | + | + | |
| Plasmablasts | – | + | – | |
| Plasma cells | – | + | – | |
High Grade Lymphoma:BCL vs TCL Return to Top | |||||
| Lymphomas | CD20 | CD45R | CD43 | CD45RO | CD3 |
| Low Grade BCL | + | + | – | – | – |
| High Grade BCL | + | + | – | – | – |
| Low Grade TCL | – | – | + | + | + |
| High Grade TCL | – | – | + | + | +/- |
Follicular Lymphoma vs Reactive Follicles Return to Top | ||||
| Lymphomas | bcl-2 | bcl-6 | CD10 | Ki-67 |
| Follicular Lymphoma | + | + | + | – |
| Reactive Follicles | – | + | + | + |
Mastocytosis Return to Top | |||||
| Lymphomas | Tryptase | CD117 | CD25 | CD163 | CD2 |
| Mastocytosis | + | + | + | – | + |
| Reactive Mast Cells | + | + | – | + | – |
| Myelomastocytic Leukemia | + | + | – | – | |
Splenic Hematopoietic Proliferations in Neoplastic and Benign Disorders Return to Top | |||||
| Lymphomas | MPO | CD34 | CD117 | CD68 | Hemoglobin A |
| Chronic Myelogenous Leukemia | + | -/+ | +/- | + | – |
| Chronic Idiopathic Myelofibrosis | + | +/- | -/+ | – | |
| Myelodysplastic Syndrome | + | -/+ | – | ||
| Myelodysplastic / Myeloproliferative Disorders | + | – | – | + | – |
| Mastocytosis | + | – | + | – | |
| Erythroid Disorders | +/- | – | – | -/+ | + |
| Splenic Lymphoma | -/+ | – | – | – | |
| Acute Myeloid Leukemia | + | + | + | + | – |
| Polycythemia Vera | + | + | + | ||