IHC of PolyDetector DAB HRP Brown staining HPV on FFPE Cervix Tissue
IHC of PolyDetector DAB HRP Brown staining MSH6 on FFPE Colon Tissue
IHC of PolyDetector DAB HRP Brown staining CK8/18 on FFPE Colon Tissue
| Intended Use | For In Vitro Diagnostic Use | |||||||||||||||||||
| Summary and Explanation | The PolyDetector DAB HRP Brown Immunohistochemistry (IHC) detection system from Bio SB, is a one-step polymeric, non-Biotin, Fab micropolymer detection system that allows for the demonstration of antigens in formalin-fixed paraffin-embedded tissues, cryostat sections, blood smears, cytosmears, and cell preparations. The PolyDetector technology was developed and is manufactured with a proprietary micropolymer backbone conjugated to anti-mouse and anti-rabbit Fab Ig’s plus high quality HRP or AP enzymes. The elimination of the anti-mouse and anti-rabbit immunoglobulin Fc region reduces non-specific reactions. This ensures consistent and reproducible immunostaining for all types of nuclear, cytoplasmic and membranous antigens, in different types of tissues. The PolyDetector is a universal IHC detection system which is optimized for use with Bio SB mouse or rabbit primary antibodies; however, these universal kits could be optimized to work with prediluted and concentrated antibodies from other vendors. The increased sensitivity of this detection system allows for rapid staining procedures without compromising stain quality. | |||||||||||||||||||
| Presentation | The Mouse/Rabbit PolyDetector DAB HRP Brown Detection System contains a peroxidase blocker, anti-mouse/rabbit immunoglobulin conjugated to horseradish peroxidase, a DAB buffer, and a DAB chromogen solution. All components are buffered with stabilizers and an anti-microbial agent. | |||||||||||||||||||
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Synonyms: impress polymer, polymer based detection, poly-detector, poly detector, micropolymer ihc, micropolymer detection, mycripolymer ihc kit, ihc, immunohistochemistry detection system, ihc detection system, DAB, dab brown, dab immunohistochemistry
Product Citations:
Biomed Red Int “HPV16-E6 Oncoprotein Activates TGF-β and Wnt/β-Catenin Pathways in the Epithelium-Mesenchymal Transition of Cataracts in a Transgenic Mouse Model”.
Cells. “Fatty Acid and Lipopolysaccharide Effect on Beta Cells Proteostasis and its Impact on Insulin Secretion”.
Scientific Reports. “Roscovitine effectively enhances antitumor activity of temozolomide in vitro and in vivo mediated by increased autophagy and Caspase-3 dependent apoptosis”.
International Journal of Molecular Sciences. “Osteochondral Tissue Regeneration Using a Tyramine-Modified Bilayered PLGA Scaffold Combined with Articular Chondrocytes in a Porcine Model”.