p16 Antibody Immunohistochemistry on a FFPE Mucoepidermoid Carcinoma Tissue
| Intended Use | For In Vitro Diagnostic Use | |||||||||||||||||||||||||||||||||||
| Summary and Explanation | p16 is a tumor suppressor gene. p16 is an important gene in regulating the cell cycle. p16INK4a regulates the cell cycle by binding and deactivating various cyclin-CDK complexes. p16 is a G1/S-cell cycle regulator that is involved in the pathway that converges in the tumor suppressor protein Rb. | |||||||||||||||||||||||||||||||||||
| Antibody Type | Rabbit Monoclonal | Clone | RM267 | |||||||||||||||||||||||||||||||||
| Isotype | IgG | Reactivity | Paraffin, Frozen | |||||||||||||||||||||||||||||||||
| Localization | Cytoplasmic, Nuclear | Control | Testis, NSCLC, TCC | |||||||||||||||||||||||||||||||||
| Presentation | Anti-p16 is a rabbit monoclonal antibody for immunohistochemistry derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative. | |||||||||||||||||||||||||||||||||||
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| Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product. | ||||||||||||||||||||||||||||||||||||
