| Intended Use | For In Vitro Diagnostic Use | |||||||||||||||||||||
| Summary and Explanation | ImmunoDNA Digestor is used for the enzymatic digestion of paraffin-embedded, formalin-fixed tissues prior to immunohistochemical (IHC) or in situ hybridization (ISH) procedures. The enzymatic digestion of formalin-fixed tissues improves accessibility of antibodies and DNA probes to target sites within tissue sections. In the case of IHC, proteolytic digestion exposes certain epitopes which have been masked during fixation. In ISH procedures, accessibility of tissue nucleic acid sequences is enhanced, allowing better probe penetration and hybridization. | |||||||||||||||||||||
| Presentation | ImmunoDNA Digestor is provided in liquid form ready-to-use. It contains optimized Proteinase K, a buffer solution, detergents, and a sodium azide anti-microbial. | |||||||||||||||||||||
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