Galectin-3 Antibody Immunohistochemistry on an FFPE Kidney Tissue
| Intended Use | For In Vitro Diagnostic Use | |||||||||||||||||||||||||||||||||||
| Summary and Explanation | Galectin-3 is a 31 kDa beta-galactosidase binding lectin. It has been associated with binding to the basement membrane glycoprotein laminin. Galectin-3 is normally distributed in epithelia of many organs and various inflammatory cells, including macrophages, as well as dendritic cells and Kupffer cells. The expression of this lectin is up-regulated during inflammation, cell proliferation, cell differentiation and through trans-activation by viral proteins. Galectin-3 antibody has been demonstrated to be valuable in differentiating between benign and malignant thyroid neoplasms in both histologic sections and Fine Needle Aspiration Biopsy material. Galectin-3 antibody has also been useful in identifying Anaplastic Large Cell Lymphoma. | |||||||||||||||||||||||||||||||||||
| Antibody Type | Mouse Monoclonal | Clone | 9C4 | |||||||||||||||||||||||||||||||||
| Isotype | IgG1 | Reactivity | Paraffin, Frozen | |||||||||||||||||||||||||||||||||
| Localization | Cytoplasmic | Control | Kidney, Testis, Salivary Gland, Breast, Tonsil, Colon, Papillary, Follcular Carcinoma of Thyroid | |||||||||||||||||||||||||||||||||
| Presentation | Galectin-3 is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative. | |||||||||||||||||||||||||||||||||||
| Availability |
| |||||||||||||||||||||||||||||||||||
| Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product. | ||||||||||||||||||||||||||||||||||||
