Positive for T cell subsets: CD4, CD8, CD68, FoxP3
Immune regulators: PD-L1, PD-L2, CTLA-4, B7H3, B7H4, OX-40
IHC using the PolyDetector Plus HRP/DAB in TintoStainer
A1C4 – Normal Human Lung Fibroblast |
B1BLANK |
C1PD-L1 Breast Carcinoma |
D1B7H3 + Metastatic Breast Cancer from pleural effusion |
A2CTLA4 + Malignant Melanoma Brain Metastasis |
B2FOX P3 + Colorectal Adenocarcinoma |
C2CD68 + Metastatic Breast Cancer from pleural effusion |
D2B7H3 + Malignant Melanoma, Skin |
A3CD4 + Acute Lymphoblastic Leukemia |
B3PD-L1 + Metastatic Prostate Cancer from Lymph Node |
C3PD-L1 + Mesothelioma Lung Cancer |
D3OX-40 + Acute Myelogenous Leukemia |
| Intended Use | For Laboratory Use | |||||||||
| Summary and Explanation | The 11-Core Immunotherapy Cell Line Microarray consist of 11- 2 mm cores of formalin-fixed paraffin-embedded cell lines which were assembled in array fashion to allow multiplex molecular pathology analysis and validation of reagents, or to be used as tissue controls for Immunohistochemistry and/or in situ hybridization (CISH and FISH) applications. | |||||||||
| Presentation | Five slides with 11- 2 mm cores, mounted on Hydrophilic Plus Slides (BSB 7028) are provided in a plastic mailer. | |||||||||
| Availability |
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