Bio SB, through its distribution partnership with ZytoVision of Germany offers one of the largest arrays of CISH & FISH product lines in the molecular pathology industry. ZytoFast® and Zytodot® offer a wide variety of Chromegenic (CISH) solutions. For those interested in implementing Flourescent (FISH) based technologies, the ZytoLight® product line offers over 100 single, dual, triple and quadruple color probes.
Brighter Signals – Superior Background
ZytoLight system uses directly labeled FISH probes, which eliminate the need to detect the probes with fluorophore-coupled antibodies. The unique ZytoLight Direct Label System II and ZytoLight Repeat Subtraction Technique provide improved signal intensity and lead to advanced specificity and less background of all our probes. ZytoLight products allow for reliable, highly sensitive and specific detection of genetic aberrations (e.g. translocations, deletions, amplifications and chromosomal aneuploidies). The innovative TriCheckTM probe design enables the user to discriminate three different gene states using just one probe.
Bringing Flexibility to Your FISH
FlexISH products are designed for the identification of genetic aberrations by FISH. Using these products gives you the flexibility to choose between a 1-day or a 2-day FISH protocol according to your laboratory workflow. The unique DistinguISHTM probes allow to detect rearrangements of two independent genes on a single specimen, like the FlexISH ALK/ROS1 DistinguISHTM probe.
Imroved Signals – Less Hands On Time
ZytoDot 2CTM products are designed to simultaneously detect two different genomic targets by chromogenic in situ hybridization (CISH) by using light microscopy. This two-colour system is especially useful for the differentiation of aneuploidies from gene amplifications and the detection of deletions and translocations.
Outstandingly Fast and Sensitive CISH
ZytoFast PLUS products are designed for outstandingly fast and sensitive detection and discrimination of human pathogen viruses such as human papillomavirus (HPV), Epstein-Barr virus (EBV) and cytomegalovirus (CMV), and for the determination of lymphocyte clonality by detecting Ig-kappa and Ig-lambda light chain mRNA by chromogenic in situ hybridization (CISH).