{"title":"Direct Immunofluorescence","description":"","products":[{"product_id":"pi3000","title":"Albumin\\FITC","description":"\u003cp\u003eThe albumins are a family of globular proteins, the most common of which are the serum albumins. Albumins are commonly found in blood plasma and differ from other blood proteins in that they are not glycosylated. Albumin functions primarily as a carrier protein for steroids, fatty acids, and thyroid hormones and plays a role in stabilizing extracellular fluid volume. Mutations in this gene on chromosome 4 result in various anomalous proteins.\n\u003cbr\u003e \n\u003cbr\u003e Low albumin (hypoalbuminemia) may be caused by liver disease, nephrotic syndrome, burns, protein-losing enteropathy, malabsorption, malnutrition, late pregnancy, artefact, genetic variations and malignancy. High albumin (hyperalbuminemia) is almost always caused by dehydration. In some cases of retinol (Vitamin A) deficiency, the albumin level can be elevated to high-normal values.\n\u003cbr\u003e \n\u003cbr\u003e It has been reported in systemic lupus erythematosus (SLE) patients an increased prevalence of IgG autoantibodies against human serum albumin (anti-HSA IgG) that are associated with SLE disease activity.\u003c\/p\u003e","brand":"biosb","offers":[{"title":"BSB-3000-3,3.0 mL,Tinto Predilute","offer_id":49735302971632,"sku":"BSB-3000-3","price":163.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3000-7,7.0 mL,Tinto Predilute","offer_id":49735303004400,"sku":"BSB-3000-7","price":272.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3000-15,15.0 mL,Tinto Predilute","offer_id":49735303037168,"sku":"BSB-3000-15","price":455.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3000-05,0.5 mL,Concentrate","offer_id":49735303069936,"sku":"BSB-3000-05","price":354.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3000-1,1.0 mL,Concentrate","offer_id":49735303102704,"sku":"BSB-3000-1","price":590.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0686\/3660\/6704\/files\/PI3000.jpg?v=1778682101"},{"product_id":"pi3001","title":"C1q\\FITC","description":"\u003cp\u003eThe complement component 1q (C1q) is a protein complex involved in the complement system, which is part of the innate immune system. C1q together with C1r and C1s form the C1 complex. Antibodies of the adaptive immune system can bind antigen, forming an antigen-antibody complex. When C1q binds antigen-antibody complexes, the C1 complex becomes activated. Activation of the C1 complex initiates the classical complement pathway of the complement system.\n\u003cbr\u003e \n\u003cbr\u003e C1q nephropathy is a rare glomerular disease with characteristic mesangial C1q deposition noted on IHC or IF microscopy. It is histologically defined and poorly understood. Light microscopic features are heterogeneous and comprise minimal change disease (MCD), focal segmental glomerulosclerosis (FSGS), and proliferative glomerulonephritis. Clinical presentation is also diverse, and ranges from asymptomatic hematuria or proteinuria to frank nephritic or nephrotic syndrome in both children and adults. Hypertension and renal insufficiency at the time of diagnosis are common findings. Lupus nephritis is an inflammation of the kidneys caused by Systemic Lupus Erythematosus. Immunofluorescence reveals positively for IgG, IgA, IgM, C3, and C1q.\u003c\/p\u003e","brand":"biosb","offers":[{"title":"BSB-3001-3,3.0 mL,Tinto Predilute","offer_id":49735324467440,"sku":"BSB-3001-3","price":163.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3001-7,7.0 mL,Tinto Predilute","offer_id":49735324500208,"sku":"BSB-3001-7","price":272.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3001-15,15.0 mL,Tinto Predilute","offer_id":49735324532976,"sku":"BSB-3001-15","price":455.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3001-05,0.5 mL,Concentrate","offer_id":49735324565744,"sku":"BSB-3001-05","price":340.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3001-1,1.0 mL,Concentrate","offer_id":49735324598512,"sku":"BSB-3001-1","price":568.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0686\/3660\/6704\/files\/PI3001.jpg?v=1778740742"},{"product_id":"pi3002","title":"C3c\\FITC","description":"\u003cp\u003eComplement component 3, often simply called C3, is a protein of the immune system. It plays a central role in the complement system and contributes to innate immunity.\n\u003cbr\u003e \n\u003cbr\u003e C3 glomerulopathy was recently coined to describe renal biopsy appearances characterized by the presence of glomerular deposits composed predominantly of C3 in the absence of significant amounts of Ig. The presence of C3 in the absence of Ig suggests activation of complement by antibody-independent pathways, typically the alternative pathway, and many patients with this type of renal lesion have evidence of genetic or acquired alternative pathway dysregulation. C3 glomerulopathy has been further divided into dense deposit disease (DDD) and C3 glomerulonephritis (C3GN) based on electron microscopy (EM) appearances. The underlying genetic defect has been identified in some hereditary forms of C3GN such as CFHR5 nephropathy. Lupus nephritis is an inflammation of the kidneys caused by Systemic Lupus Erythematosus. Immunofluorescence reveals positively for IgG, IgA, IgM, C3, and C1q.\u003c\/p\u003e","brand":"biosb","offers":[{"title":"BSB-3002-3,3.0 mL,Tinto Predilute","offer_id":49735324827888,"sku":"BSB-3002-3","price":156.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3002-7,7.0 mL,Tinto Predilute","offer_id":49735324860656,"sku":"BSB-3002-7","price":261.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3002-15,15.0 mL,Tinto Predilute","offer_id":49735324893424,"sku":"BSB-3002-15","price":434.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3002-05,0.5 mL,Concentrate","offer_id":49735324926192,"sku":"BSB-3002-05","price":325.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3002-1,1.0 mL,Concentrate","offer_id":49735324958960,"sku":"BSB-3002-1","price":542.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0686\/3660\/6704\/files\/PI3002.jpg?v=1778740858"},{"product_id":"pi3003","title":"C4c\/FITC","description":"\u003cp\u003eComplement component 4 (C4), in humans, is a protein involved in the intricate complement system, originating from the human leukocyte antigen(HLA) system. It serves several critical functions in immunity, tolerance, and autoimmunity with the other numerous components.\n\u003cbr\u003e \n\u003cbr\u003e Low serum complement activity or low protein concentrations of complement C4 are found on Systemic Lupus Erythematosus (SLE) and it is often associated with Congenital C4 deficiency. Complete deficiencies of complement components are among the strongest genetic risk factors for SLE or lupus-like disease, across HLA haplotypes and racial backgrounds.\u003c\/p\u003e","brand":"biosb","offers":[{"title":"BSB-3003-3,3.0 mL,Tinto Predilute","offer_id":49735325942000,"sku":"BSB-3003-3","price":156.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3003-7,7.0 mL,Tinto Predilute","offer_id":49735325974768,"sku":"BSB-3003-7","price":261.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3003-15,15.0 mL,Tinto Predilute","offer_id":49735326007536,"sku":"BSB-3003-15","price":434.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3003-05,0.5 mL,Concentrate","offer_id":49735326040304,"sku":"BSB-3003-05","price":325.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3003-1,1.0 mL,Concentrate","offer_id":49735326073072,"sku":"BSB-3003-1","price":542.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0686\/3660\/6704\/files\/PI3003.jpg?v=1778741097"},{"product_id":"pi3004","title":"Fibrinogen\\FITC","description":"\u003cp\u003eFibrinogen (factor I) is a glycoprotein that circulates in the blood of vertebrates. During tissue and vascular injury, it is converted enzymatically by thrombin to fibrin and subsequently to a fibrin-based blood clot. Fibrinogen functions primarily to occlude blood vessels and thereby stop excessive bleeding. Fibrin also mediates blood platelet and endothelial cell spreading, tissue fibroblast proliferation, capillary tube formation, and angiogenesis and thereby functions to promote tissue revascularization, wound healing, and tissue repair.\n\u003cbr\u003e \n\u003cbr\u003e Several disorders (Congenital afibrinogenemia, hypofibrinogenemia, Fibrinogen storage disease, Hereditary fibrinogen Aα-Chain amyloidosis, Congenital hypodysfibrinogenemia, Cryofibrinogenemia, acquired hypofibrinogenemia, Chronic Kidney Disease, etc.) in the quantity and\/or quality of fibrinogen cause pathological bleeding, pathological blood clotting, and\/or the deposition of fibrinogen in the liver, kidneys, and other tissues. Chronic kidney disease (CKD) patients have increased rates of bleeding as well as thrombosis. Fibrinogen and platelets combine to generate a mature clot, but in CKD platelets are dysfunctional.\u003c\/p\u003e","brand":"biosb","offers":[{"title":"BSB-3004-3,3.0 mL,Predilute","offer_id":49735410680048,"sku":"BSB-3004-3","price":163.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3004-7,7.0 mL,Predilute","offer_id":49735410712816,"sku":"BSB-3004-7","price":272.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3004-15,15.0 mL,Predilute","offer_id":49735410745584,"sku":"BSB-3004-15","price":455.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3004-05,0.5 mL,Concentrate","offer_id":49735410778352,"sku":"BSB-3004-05","price":354.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3004-1,1.0 mL,Concentrate","offer_id":49735410811120,"sku":"BSB-3004-1","price":590.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0686\/3660\/6704\/files\/PI3004.jpg?v=1778762699"},{"product_id":"pi3005","title":"IgA\\FITC","description":"\u003cp\u003eImmunoglobulin A (IgA) is the main immunoglobulin in mucous secretions, including tears, saliva, and colostrum, as well as respiratory, intestinal, prostatic, and vaginal secretions. It is also found in small amounts in blood. Because it is resistant to degradation by enzymes, secretory IgA provides protection against microbes proliferating in body secretions, especially those of the digestive and respiratory tracts.\n\u003cbr\u003e \n\u003cbr\u003e IgA antibody reacts with surface immunoglobulin IgA alpha chains. It is extremely useful when identifying Acute Leukemias, IgA Myelomas, Plasmacytomas, and B-cell lineage derived Hodgkin’s Lymphomas. However, due to the restricted expression of heavy and light chains in these diseases, demonstration of B-cell Lymphomas is possible with clonal gene-rearrangement studies. Lupus nephritis is an inflammation of the kidneys caused by Systemic Lupus Erythematosus. Immunofluorescence reveals positively for IgG, IgA, IgM, C3, and C1q.\u003c\/p\u003e","brand":"biosb","offers":[{"title":"BSB-3005-3,3.0 mL,Predilute","offer_id":49735557316848,"sku":"BSB-3005-3","price":156.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3005-7,7.0 mL,Predilute","offer_id":49735557349616,"sku":"BSB-3005-7","price":261.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3005-15,15.0 mL,Predilute","offer_id":49735557382384,"sku":"BSB-3005-15","price":434.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3005-05,0.5 mL,Concentrate","offer_id":49735557415152,"sku":"BSB-3005-05","price":325.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3005-1,1.0 mL,Concentrate","offer_id":49735557447920,"sku":"BSB-3005-1","price":542.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0686\/3660\/6704\/files\/PI3005.jpg?v=1778772702"},{"product_id":"pi3006","title":"IgD\\FITC","description":"\u003cp\u003eIgD makes up about 1% of proteins in the plasma membranes of immature B-lymphocytes (coexpressed with IgM) and is also found in serum in very small amounts. It is monomeric and incorporates the alpha-heavy chain in its structure. IgD’s function is currently unknown, as mice lacking IgD seem to retain normal immune responses (implying redundancy if not lack of function), and IgD ceases to be expressed in activated B-lymphocytes. It may function as a regulatory antigen receptor. IgD is the major antigen receptor isotype co-expressed with IgM on the surface of most peripheral B cells in mice and humans.\n\u003cbr\u003e \n\u003cbr\u003e The IgD antibody reacts with surface immunoglobulin IgD delta chains. This antibody is useful when identifying Leukemias, Plasmacytomas, and B-cell lineage derived from Lymphomas, specifically Marginal Zone Lymphoma. Renal involvement in systemic lupus erythematosus (SLE) is associated with production of antibodies to double stranded DNA, deposition of immune complexes and organ damage. Lupus nephritis patients were characterized by increased percentage of immature\/early-transitional B-cells (CD27-IgD+CD21-), higher frequency of activated switched memory (SM, CD27+IgD-CD21-) and exhausted memory B-cells (CD27-IgD-), and decrease in non-switched memory (NSM, CD27+IgD+) B-cells.\u003c\/p\u003e","brand":"biosb","offers":[{"title":"BSB-3006-3,3.0 mL,Predilute","offer_id":49735558627568,"sku":"BSB-3006-3","price":156.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3006-7,7.0 mL,Predilute","offer_id":49735558660336,"sku":"BSB-3006-7","price":261.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3006-15,15.0 mL,Predilute","offer_id":49735558693104,"sku":"BSB-3006-15","price":434.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3006-05,0.5 mL,Concentrate","offer_id":49735558725872,"sku":"BSB-3006-05","price":337.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3006-1,1.0 mL,Concentrate","offer_id":49735558758640,"sku":"BSB-3006-1","price":563.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0686\/3660\/6704\/files\/PI3006.jpg?v=1778772790"},{"product_id":"pi3011","title":"IgE\\FITC","description":"\u003cp\u003eIgE, Immunoglobulin E, is an isotype of antibody only found in mammals. IgE is synthesized by plasma cells. Monomers of IgE consist of two heavy chains (ε chain) and two light chains, with the ε chain containing 4 Ig-like constant domains (Cε1-Cε4). IgE's main function is immunity to parasites such as helminths like Schistosoma mansoni, Trichinella spiralis, and Fasciola hepatica. IgE is utilized during immune defense against certain protozoan parasites such as Plasmodium falciparum.\n\u003cbr\u003e \n\u003cbr\u003e IgE also has an essential role in type I hypersensitivity, which manifests in various allergic diseases, such as allergic asthma, most types of sinusitis, allergic rhinitis, food allergies, and specific types of chronic urticaria and atopic dermatitis. IgE also plays a pivotal role in responses to allergens, such as: anaphylactic drugs, bee stings, and antigen preparations used in desensitization immunotherapy. IgE is known to be elevated in various autoimmune disorders such as Lupus (SLE), Rheumatoid Arthritis(RA) \u0026amp; psoriasis, and is theorized to be of pathogenetic importance in RA and SLE by eliciting a hypersensitivity reaction.\u003c\/p\u003e","brand":"biosb","offers":[{"title":"BSB-3011-3,3.0 mL,Predilute","offer_id":49735559381232,"sku":"BSB-3011-3","price":156.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3011-7,7.0 mL,Predilute","offer_id":49735559414000,"sku":"BSB-3011-7","price":261.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3011-15,15.0 mL,Predilute","offer_id":49735559446768,"sku":"BSB-3011-15","price":434.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3011-05,0.5 mL,Concentrate","offer_id":49735559479536,"sku":"BSB-3011-05","price":325.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3011-1,1.0 mL,Concentrate","offer_id":49735559512304,"sku":"BSB-3011-1","price":542.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0686\/3660\/6704\/files\/PI3011.jpg?v=1778772878"},{"product_id":"pi3007","title":"IgG\\FITC","description":"\u003cp\u003eIgG is a monomeric immunoglobulin, comprised of two heavy chains and two light chains. This is the most abundant immunoglobulin and is approximately equally distributed in blood and tissue liquids, constituting 75% of serum immunoglobulins in humans. This is the only isotype that can pass through the placenta and bind to many kinds of pathogens. IgG protects the body against them by complement activation (classic pathway), opsonization for phagocytosis and neutralization of their toxins. There are 4 subclasses: IgG1 (66%), IgG2 (23%), IgG3 (7%) and IgG4 (4%).\n\u003cbr\u003e \n\u003cbr\u003e IgG antibody reacts with surface immunoglobulin IgG gamma chains. This antibody is useful when identifying Leukemias, Plasmacytomas, and B-cell lineage derived Hodgkin’s Lymphomas. Due to the restricted expression of heavy and light chains in these diseases, demonstration of B-cell Lymphomas is possible with clonal gene-rearrangement studies. Lupus nephritis is an inflammation of the kidneys caused by Systemic Lupus Erythematosus. Immunofluorescence reveals positively for IgG, IgA, IgM, C3, and C1q. Clinically, hematuria and proteinuria are present, with or without nephrotic syndromes. Mesangial IgG glomerulonephritis has been recently recognized as a distinct type of glomerulonephritis. The morphologic criteria detected in these patients included mesangial dense deposits by ultra ¬structural studies, which were predominantly positive for IgG by immunofluorescence.\u003c\/p\u003e","brand":"biosb","offers":[{"title":"BSB-3007-3,3.0 mL,Predilute","offer_id":49735560167664,"sku":"BSB-3007-3","price":156.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3007-7,7.0 mL,Predilute","offer_id":49735560200432,"sku":"BSB-3007-7","price":261.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3007-15,15.0 mL,Predilute","offer_id":49735560233200,"sku":"BSB-3007-15","price":434.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3007-05,0.5 mL,Concentrate","offer_id":49735560265968,"sku":"BSB-3007-05","price":325.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3007-1,1.0 mL,Concentrate","offer_id":49735560298736,"sku":"BSB-3007-1","price":542.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0686\/3660\/6704\/files\/PI3007.jpg?v=1778772960"},{"product_id":"pi3008","title":"IgM\\FITC","description":"\u003cp\u003eIgM forms polymers where multiple immunoglobulins are covalently linked together with disulfide bonds, normally as a pentamer or occasionally as a hexamer. It has a large molecular mass of approximately 900 kDa (in its pentamer form). In germline cells, the gene segment encoding the constant region of the heavy chain is positioned first among other constant region gene segments. For this reason, IgM is the first immunoglobulin expressed by mature B-cells.\n\u003cbr\u003e \n\u003cbr\u003e IgM antibody reacts with surface immunoglobulin IgM mu chains. IgM is one of the predominant surface immunoglobulins on B-lymphocytes, and is useful when identifying Leukemias, Plasmacytomas, and B-cell lineage derived Hodgkin’s Lymphomas. Due to the restricted expression of heavy and light chains in these diseases, demonstration of B-cell Lymphomas is possible with clonal gene-rearrangement studies. Lupus nephritis is an inflammation of the kidneys caused by Systemic Lupus Erythematosus. Immunofluorescence reveals positively for IgG, IgA, IgM, C3, and C1q. Clinically, hematuria and proteinuria are present, with or without nephrotic syndromes. Immunoglobulin M (IgM) nephropathy is an uncommon glomerular disease characterized by IgM deposits in the mesangium.\u003c\/p\u003e","brand":"biosb","offers":[{"title":"BSB-3008-3,3.0 mL,Tinto Predilute","offer_id":49735562166512,"sku":"BSB-3008-3","price":156.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3008-7,7.0 mL,Tinto Predilute","offer_id":49735562199280,"sku":"BSB-3008-7","price":261.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3008-15,15.0 mL,Tinto Predilute","offer_id":49735562232048,"sku":"BSB-3008-15","price":434.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3008-05,0.5 mL,Concentrate","offer_id":49735562264816,"sku":"BSB-3008-05","price":325.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3008-1,1.0 mL,Concentrate","offer_id":49735562297584,"sku":"BSB-3008-1","price":542.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0686\/3660\/6704\/files\/PI3008.jpg?v=1778773443"},{"product_id":"pi3009","title":"Kappa Light Chains\\FITC","description":"\u003cp\u003eKappa detects surface immunoglobulin on normal and neoplastic B-cells. In paraffin-embedded tissue, Kappa exhibits strong staining of kappa-positive plasma cells and cells that have absorbed exogenous immunoglobulin.\n\u003cbr\u003e \n\u003cbr\u003e When studying B-cell neoplasms, the determination of light-chain ratios remains the centerpiece. This is sound reasoning because most B-cell Lymphomas express either Kappa or Lambda light chains, whereas reactive proliferations display a mixture of Kappa and Lambda-positive cells. If only a single light-chain type is detected, a lympho-proliferative disorder is very likely. Monoclonality is determined by a Kappa-Lambda ratio greater than or equal to 3:1, a Lambda-Kappa ratio greater than or equal to 2:1, or a monoclonal population of 75% or more of the total population. In IgG-dominant immune complex-mediated glomerulonephritis, there are multiple pathological findings that strongly suggest the diagnosis of Lupus Nephritis including immunofluorescence staining for IgG, IgM, IgA, Kappa or Lambda, C3 and C1.\u003c\/p\u003e","brand":"biosb","offers":[{"title":"BSB-3009-3,3.0 mL,Predilute","offer_id":49735569211632,"sku":"BSB-3009-3","price":156.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3009-7,7.0 mL,Predilute","offer_id":49735569244400,"sku":"BSB-3009-7","price":261.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3009-15,15.0 mL,Predilute","offer_id":49735569277168,"sku":"BSB-3009-15","price":434.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3009-05,0.5 mL,Concentrate","offer_id":49735569309936,"sku":"BSB-3009-05","price":325.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3009-1,1.0 mL,Concentrate","offer_id":49735569342704,"sku":"BSB-3009-1","price":542.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0686\/3660\/6704\/files\/PI3009.jpg?v=1778774693"},{"product_id":"pi3010","title":"Lambda\\FITC","description":"\u003cp\u003eLambda detects surface immunoglobulin on normal and neoplastic B-cells. Lambda staining is seen in B-cell follicles of human lymphoid tissue.\n\u003cbr\u003e \n\u003cbr\u003e When studying B-cell neoplasms, the determination of light chain ratios remains the centerpiece. This is sound reasoning because most B-cell Lymphomas express either kappa or lambda light chains, whereas reactive proliferations display a mixture of kappa and lambda-positive cells. If only a single light-chain type is detected, a lymphoproliferative disorder is very likely. Monoclonality is determined by a kappa-lambda ratio greater than or equal to 3:1, a lambda-kappa ratio greater than or equal to 2:1, or a monoclonal population of 75% or more of the total population. In IgG-dominant immune complex-mediated glomerulonephritis, there are multiple pathological findings that strongly suggest the diagnosis of Lupus Nephritis including immunofluorescence staining for IgG, IgM, IgA, Kappa or Lambda, C3 and C1.\u003c\/p\u003e","brand":"biosb","offers":[{"title":"BSB-3010-3,3.0 mL,Predilute","offer_id":49735573045488,"sku":"BSB-3010-3","price":163.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3010-7,7.0 mL,Predilute","offer_id":49735573078256,"sku":"BSB-3010-7","price":272.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3010-15,15.0 mL,Predilute","offer_id":49735573111024,"sku":"BSB-3010-15","price":455.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3010-05,0.5 mL,Concentrate","offer_id":49735573143792,"sku":"BSB-3010-05","price":340.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3010-1,1.0 mL,Concentrate","offer_id":49735573176560,"sku":"BSB-3010-1","price":568.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0686\/3660\/6704\/files\/PI3010.jpg?v=1778828407"}],"url":"https:\/\/www.biosb.com\/collections\/direct-immunofluorescence.oembed","provider":"Biosb","version":"1.0","type":"link"}