{"title":"Deparaffinator Solutions","description":"","products":[{"product_id":"pi0102","title":"ImmunoDetector Biotin Blocker","description":"\u003cp\u003eImmunoDetector Biotin Blocker is a two-step endogenous biotin blocking system used for immunohistochemistry (IHC)\n\u003cbr\u003e and in-situ hybridization (ISH) procedures. This blocking system is useful for blocking endogenous biotin in both frozen\n\u003cbr\u003e and formalin-fixed paraffin-embedded (FFPE) tissues (pancreas, kidney, liver, etc.) that contain higher levels of biotin that\n\u003cbr\u003e may yield false positive results. It can be used in autostainers as well as manual staining procedures.\u003c\/p\u003e","brand":"biosb","offers":[{"title":"BSB 0098,Ready-to-use,15 mL","offer_id":49760312787184,"sku":"BSB 0098","price":140.0,"currency_code":"USD","in_stock":true},{"title":"BSB 0099,Ready-to-use,50 mL","offer_id":49760312819952,"sku":"BSB 0099","price":420.0,"currency_code":"USD","in_stock":true},{"title":"BSB 0100,Ready-to-use,100 mL","offer_id":49760312852720,"sku":"BSB 0100","price":772.0,"currency_code":"USD","in_stock":true},{"title":"BSB 0101,Ready-to-use,200 mL","offer_id":49760312885488,"sku":"BSB 0101","price":1403.0,"currency_code":"USD","in_stock":true},{"title":"BSB 0102,Ready-to-use,1000 mL","offer_id":49760312918256,"sku":"BSB 0102","price":6320.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0686\/3660\/6704\/files\/ImmunoDetector_Biotin_Blocker_e8895567-0457-43e9-ad12-2e76ff33c7ec.jpg?v=1779581495"},{"product_id":"pi0176","title":"TintoDeparaffinator Citrate 20X","description":"\u003cp\u003eThe TintoDeparaffinator Citrate solution is intended for paraffin removal from paraffin-embedded tissues, hydrating and\n\u003cbr\u003e heat permeabilizing tissues to achieve epitope or nucleic acid retrieval. The TintoDeparaffinator Citrate (BSB 0175 and\n\u003cbr\u003e BSB 0176) is an innovative reagent formulated to reduce exposure to toxic solvents and reduces the number of steps in\n\u003cbr\u003e deparaffinization, hydration and epitope or nucleic acid retrieval, thus making it a safe and efficient alternative to\n\u003cbr\u003e traditional deparaffinization involving the use of xylenes and alcohol. Since they do not interfere with the detection of\n\u003cbr\u003e proteins by Immunohistochemistry, Immunocytochemistry, or of nucleic acids by CISH and FISH, results are the same as\n\u003cbr\u003e when using xylene and alcohol. The deparaffinization procedure with TintoDeparaffinator Citrate solution uses a heat-assisted deparaffinization method\n\u003cbr\u003e while achieving tissue hydration and retrieval of proteins and nucleic acids. Deparaffinization at moderately elevated\n\u003cbr\u003e temperatures has been shown to adequately dissolve paraffin at significantly lower solvent concentrations compared to\n\u003cbr\u003e methods of deparaffinization at ambient temperatures using xylenes and\/or xylene substitutes. By utilizing lower non-toxic solvent concentrations, the process of tissue rehydration following deparaffinization and\n\u003cbr\u003e retrieval can be achieved with a single final rinse step to remove micro-paraffin leftovers, followed by direct transfer of\n\u003cbr\u003e slides to a buffer bath. These reagents are specifically designed to work with the Bio SB TintoRetriever Pressure Cooker\n\u003cbr\u003e (BSB 7008) or TintoRetriever PT Module (BSB 7030 and BSB 7033), but may be used with any heating device that\n\u003cbr\u003e provides the required temperature. These reagents are designed to deparaffinize, rehydrate and retrieve one microscope slide containing a standard size\n\u003cbr\u003e (from 0.5cm x 1cm up to 2.5cm x 2.5cm diameter) paraffin-embedded tissue section per 3 ml of TintoDeparaffinator\n\u003cbr\u003e Citrate 1X. A typical staining dish containing 200-250 ml will deparaffinize approximately 72 standard tissue sections. If\n\u003cbr\u003e larger tissue sections are used, the number of processed slides may be less. If residual paraffin is observed\n\u003cbr\u003e microscopically on the slides following deparaffinization, the deparaffinization reagents should be replaced. The TintoDeparaffinator Hot Rinse (BSB 0179 and BSB 0180) may be used as the final rinse step in order to remove\n\u003cbr\u003e residual micro-paraffin, but is optional. Refer to BSB 0180 TintoDeparaffinator Hot Rinse 20X. ChromoProtector (BSB 0151, BSB 0152 and BSB 0153) is highly recommended to be used after the intended staining\n\u003cbr\u003e procedure in order to remove any significant micro-paraffin that may be leftover before mounting slide with a coverslip. For optimal results, it is recommended to use both TintoDeparaffinator Hot Rinse and ChromoProtector to remove all\n\u003cbr\u003e micro-paraffin.\u003c\/p\u003e","brand":"biosb","offers":[{"title":"BSB 0175,TintoDeparaffinator Citrate 20X,100 mL","offer_id":49760314851568,"sku":"BSB 0175","price":156.0,"currency_code":"USD","in_stock":true},{"title":"BSB 0176,TintoDeparaffinator Citrate 20X,1 L","offer_id":49760314884336,"sku":"BSB 0176","price":974.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0686\/3660\/6704\/files\/TintoDeparaffinator_Citrate_20X_ea83c935-2d01-4033-848c-384d172cc3d0.jpg?v=1779581603"},{"product_id":"pi0178","title":"TintoDeparaffinator EDTA 20X","description":"\u003cp\u003eTintoCitrate may be used whenever immuno staining is performed on formalin-fixed, paraffin-embedded tissue sections. Using this product encourages standardization of the pretreatment procedure, thereby producing more consistent, more reliable results.\u003c\/p\u003e","brand":"biosb","offers":[{"title":"BSB 0177,TintoDeparaffinator Citrate 20X,100 mL","offer_id":49760314917104,"sku":"BSB 0177","price":202.0,"currency_code":"USD","in_stock":true},{"title":"BSB 0178,TintoDeparaffinator Citrate 20X,1 L","offer_id":49760314949872,"sku":"BSB 0178","price":1265.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0686\/3660\/6704\/files\/TintoDeparaffinator_EDTA_20X_ce3327fe-bc1d-4102-a099-b97cc95491a2.jpg?v=1779581610"},{"product_id":"pi0180","title":"TintoDeparaffinator Hot Rinse 20X","description":"\u003cp\u003eThe TintoDeparaffinator Hot Rinse is part of a set of solutions intended for paraffin removal from paraffin-embedded\n\u003cbr\u003e tissues, hydrating and heat permeabilizing tissues to achieve epitope or nucleic acid retrieval. The TintoDeparaffinator Hot\n\u003cbr\u003e Rinse, TintoDeparaffinator Citrate (BSB 0175 and BSB 0176) and TintoDeparaffinator EDTA (BSB 0177 and BSB 0178),\n\u003cbr\u003e are innovative reagents formulated to reduce exposure to toxic solvents and to reduce the number of steps in\n\u003cbr\u003e deparaffinization, hydration and epitope or nucleic acid retrieval, thus making them a safe and efficient alternative to\n\u003cbr\u003e traditional deparaffinization involving xylenes and alcohols. Since they do not interfere with the detection of proteins by\n\u003cbr\u003e Immunohistochemistry, Immunocytochemistry, xylene and alcohol. The deparaffinization procedure with TintoDeparaffinator Hot Rinse, TintoDeparaffinator Citrate, and TintoDeparaffinator\n\u003cbr\u003e EDTA solutions uses a heat-assisted deparaffinization method while achieving tissue hydration and retrieval of proteins\n\u003cbr\u003e and nucleic acids. Deparaffinization at moderately elevated temperatures has been shown to adequately dissolve paraffin\n\u003cbr\u003e at significantly lower solvent concentrations compared to methods of deparaffinization at ambient temperatures using\n\u003cbr\u003e xylenes and\/or xylene substitutes. By utilizing lower non-toxic solvent concentrations, the process of tissue rehydration\n\u003cbr\u003e following deparaffinization and retrieval can be achieved with a single final rinse step to remove micro paraffin leftovers,\n\u003cbr\u003e followed by direct transfer of slides to a buffer bath. These reagents are specifically designed to work with the Bio SB\n\u003cbr\u003e TintoRetriever Pressure Cooker (BSB 7008) or TintoRetriever PT Module (BSB 7030 and BSB 7033) but may be used\n\u003cbr\u003e with any heating device that provides the required temperature. These reagents are designed to deparaffinize, rehydrate and retrieve one microscope slide containing a standard size\n\u003cbr\u003e (from 0.5cm x 1cm up to 2.5cm x 2.5cm diameter) paraffin-embedded tissue section per 3 ml of TintoDeparaffinator Hot\n\u003cbr\u003e Rinse 1X. A typical staining dish containing 200-250 ml of the TintoDeparaffinator Hot Rinse 1X solution will help\n\u003cbr\u003e deparaffinize approximately 72 standard tissue sections. If larger tissue sections are used, the number of processed\n\u003cbr\u003e slides may be less. If residual paraffin is observed microscopically on the slides following deparaffinization, the\n\u003cbr\u003e deparaffinization reagents should be replaced. TintoDeparaffinator Hot Rinse is intended to be used as a final rinse step in order to help remove residual micro-paraffin\n\u003cbr\u003e leftover on the slides after the use of heat treatment with either the TintoDeparaffinator Citrate or the TintoDeparaffinator\n\u003cbr\u003e EDTA. ChromoProtector is highly recommended to be used after the intended staining procedure in order to remove any\n\u003cbr\u003e significant micro-paraffin that may be leftover before mounting slide with a coverslip.\u003c\/p\u003e","brand":"biosb","offers":[{"title":"BSB 0179,TintoDeparaffinator Citrate 20X,100 mL","offer_id":49760314982640,"sku":"BSB 0179","price":152.0,"currency_code":"USD","in_stock":true},{"title":"BSB 0180,TintoDeparaffinator Citrate 20X,1 L","offer_id":49760315015408,"sku":"BSB 0180","price":950.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0686\/3660\/6704\/files\/TintoDeparaffinator_Hot_Rinse_20X_fc9cb6bb-df4c-4e6d-b7fe-a03e9c4995ff.jpg?v=1779581617"}],"url":"https:\/\/www.biosb.com\/collections\/deparaffinator-solutions.oembed","provider":"Biosb","version":"1.0","type":"link"}