{"title":"Antibodies","description":"","products":[{"product_id":"pi2026","title":"Oct-2","description":"\u003cp\u003eOctamer transcription factor-2 (OCT-2) possesses a leucine zipper domain and belongs to the POU family of transcription factors. It binds to the octamer motif (5-ATTTCAT-3), activates immunoglobulin gene expression and regulates transcription in a number of tissues. OCT-2 is important for the expression of B cell specific genes, such as CD20 and CRISP-3. OCT-2 is expressed in mature B cells, predominantly germinal center B cells.\n\u003cbr\u003e \n\u003cbr\u003e The OCT-2 antibody labels various B cell lymphomas with strong expression in germinal center-derived lymphomas.\u003c\/p\u003e","brand":"biosb","offers":[{"title":"BSB 2021,3.0 mL,Predilute","offer_id":49735296581872,"sku":"BSB 2021","price":346.0,"currency_code":"USD","in_stock":true},{"title":"BSB 2022,7.0 mL,Predilute","offer_id":49735296614640,"sku":"BSB 2022","price":628.0,"currency_code":"USD","in_stock":true},{"title":"BSB 2023,15.0 mL,Predilute","offer_id":49735296647408,"sku":"BSB 2023","price":1006.0,"currency_code":"USD","in_stock":true},{"title":"BSB 2024,0.1 mL,Concentrate","offer_id":49735296680176,"sku":"BSB 2024","price":245.0,"currency_code":"USD","in_stock":true},{"title":"BSB 2025,0.5 mL,Concentrate","offer_id":49735296712944,"sku":"BSB 2025","price":551.0,"currency_code":"USD","in_stock":true},{"title":"BSB 2026,1.0 mL,Concentrate","offer_id":49735296745712,"sku":"BSB 2026","price":1023.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0686\/3660\/6704\/files\/PI2026.jpg?v=1778679292"},{"product_id":"pi3502","title":"A-1-Antichymotrypsin","description":"\u003cp\u003eAlpha-1-Antichymotrypsin Glycoprotein found in alpha (1)-globulin fraction in human serum. It inhibits chymotrypsin-like proteinases in vivo and has cytotoxic killer-cell activity in vitro. The protein also has a role as an acute-phase protein and is active in the control of immunologic and inflammatory processes, and as a\n\u003cbr\u003e tumor marker. It is a member of the serpin superfamily.\n\u003cbr\u003e \n\u003cbr\u003e Alpha-1-Antichymotrypsin antibody reacts with histiocytes and histiocytic neoplasms. Its major application is defining the presence of Alpha-1-Antichymotrypsin in histiocytes and tumors derived from them. In eosinophilic granuloma and malignant histiocytosis, the reaction for this marker is heterogeneous in intensity and distribution. In fibrous histiocytomas, under certain circumstances, a diffuse homogeneous reaction may be observed.\u003c\/p\u003e","brand":"biosb","offers":[{"title":"BSB 3497,3.0 mL,Predilute","offer_id":49735296975088,"sku":"BSB 3497","price":179.0,"currency_code":"USD","in_stock":true},{"title":"BSB 3498,7.0 mL,Predilute","offer_id":49735297007856,"sku":"BSB 3498","price":326.0,"currency_code":"USD","in_stock":true},{"title":"BSB 3499,15.0 mL,Predilute","offer_id":49735297040624,"sku":"BSB 3499","price":586.0,"currency_code":"USD","in_stock":true},{"title":"BSB 3500,0.1 mL,Concentrate","offer_id":49735297073392,"sku":"BSB 3500","price":163.0,"currency_code":"USD","in_stock":true},{"title":"BSB 3501,0.5 mL,Concentrate","offer_id":49735297106160,"sku":"BSB 3501","price":324.0,"currency_code":"USD","in_stock":true},{"title":"BSB 3502,1.0 mL,Concentrate","offer_id":49735297138928,"sku":"BSB 3502","price":643.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0686\/3660\/6704\/files\/PI3502.jpg?v=1778679967"},{"product_id":"pi5013","title":"A-1-Antitrypsin","description":"\u003cp\u003eAlpha-1-Antitrypsin (A1AT) is a glycoprotein generally known as serum trypsin inhibitor. Alpha-1-Antitrypsin is also referred to as alpha-1 proteinase inhibitor (A1PI) because it is a serine protease inhibitor (serpin), inhibiting a wide variety of proteases. It protects tissues from enzymes of inflammatory cells, especially\n\u003cbr\u003e elastase, and has a reference range in blood of 1.5 - 3.5 gram\/liter (in the U.S. the reference range is generally expressed as mg\/dL or micromoles), but the concentration can rise many fold upon acute inflammation. In its absence, elastase is free to break down elastin, which contributes to the elasticity of the lungs, resulting in\n\u003cbr\u003e respiratory complications such as emphysema, or COPD (Chronic Obstructive Pulmonary Disease) in adults and cirrhosis in adults or children.\n\u003cbr\u003e \n\u003cbr\u003e Alpha-1-Antitrypsin is considered to be very useful in the study of inherited AAT deficiency, benign and Malignant Hepatic Tumors and Yolk-Sac Carcinomas. Positive staining for A-1-Antitrypsin may also be used in detection of benign and malignant lesions of a histiocytic nature. Sensitivity and specificity of the results have made this antibody a useful tool in the screening of patients with Cryptogenic Cirrhosis or other forms of liver disease with portal fibrosis of unknown etiology.\u003c\/p\u003e","brand":"biosb","offers":[{"title":"BSB 5008,3.0 mL,Predilute","offer_id":49735298285808,"sku":"BSB 5008","price":116.0,"currency_code":"USD","in_stock":true},{"title":"BSB 5009,7.0 mL,Predilute","offer_id":49735298318576,"sku":"BSB 5009","price":208.0,"currency_code":"USD","in_stock":true},{"title":"BSB 5010,15.0 mL,Predilute","offer_id":49735298351344,"sku":"BSB 5010","price":375.0,"currency_code":"USD","in_stock":true},{"title":"BSB 5011,0.1 mL,Concentrate","offer_id":49735298384112,"sku":"BSB 5011","price":130.0,"currency_code":"USD","in_stock":true},{"title":"BSB 5012,0.5 mL,Concentrate","offer_id":49735298416880,"sku":"BSB 5012","price":183.0,"currency_code":"USD","in_stock":true},{"title":"BSB 5013,1.0 mL,Concentrate","offer_id":49735298449648,"sku":"BSB 5013","price":266.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0686\/3660\/6704\/files\/PI5013.jpg?v=1778680137"},{"product_id":"pi3702","title":"ACE2","description":"\u003cp\u003eAngiotensin Converting Enzyme 2 is a dipeptidyl carboxydipeptidase active in the renin-angiotensin pathway, which helps regulate cardiovascular and renal functions. ACE2 is a secreted protein that cleaves angiotensin I (AngI) into angiotensin 1-9, and angiotensin II (AngII) into vasodilator angiotensin 1-7. ACE2 is expressed in the heart and kidney, where it may counteract vasoconstriction by inactivating Ang II. It is also found in the Gastrointestinal tract, lungs, and testis, in endothelial cells and less in vascular smooth muscle cells. ACE2 can contribute to tumor inhibition by inactivating AngII, which has been found to participate in tumor proliferation, angiogenesis, and metastasis. \n\u003cbr\u003e \n\u003cbr\u003e ACE2 has shown inhibitory effects on lung, prostate, breast, and liver cancer through various signaling mechanisms, and its expression may be correlated with immune cell penetration into the tissue. ACE2 also functions as the main receptor for the spike glycoprotein of human coronaviruses HCoV-NL63, SARS-CoV and SARS-CoV-2.\u003c\/p\u003e","brand":"biosb","offers":[{"title":"BSB-3702-3,3.0 mL,Tinto Predilute","offer_id":49735298941168,"sku":"BSB-3702-3","price":253.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3702-7,7.0 mL,Tinto Predilute","offer_id":49735298973936,"sku":"BSB-3702-7","price":461.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3702-15,15.0 mL,Tinto Predilute","offer_id":49735299006704,"sku":"BSB-3702-15","price":827.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3702-01,0.1 mL,Concentrate","offer_id":49735299039472,"sku":"BSB-3702-01","price":220.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3702-05,0.5 mL,Concentrate","offer_id":49735299072240,"sku":"BSB-3702-05","price":511.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3702-1,1.0 mL,Concentrate","offer_id":49735299105008,"sku":"BSB-3702-1","price":844.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0686\/3660\/6704\/files\/PI3702.jpg?v=1778680245"},{"product_id":"pi5020","title":"ACTH","description":"\u003cp\u003eAdrenocorticotropic Hormone (ACTH or corticotropin) is a polypeptide hormone synthesized from POMC, (Pro-opiomelanocortin) and secreted from corticotropes in the anterior lobe of the pituitary gland in response to Corticotropin-releasing Hormone (CRH) released by the hypothalamus. It consists of 39 amino acids.\n\u003cbr\u003e \n\u003cbr\u003e ACTH is a useful marker in the classification of pituitary tumors and the study of pituitary disease. It reacts with ACTH-producing cells (corticotrophs), as well as other tumors (e.g., some Small-Cell Carcinomas present in lung tissue) causing Paraneoplastic Syndromes by secreting ACTH.\u003c\/p\u003e","brand":"biosb","offers":[{"title":"BSB 5015,3.0 mL,Predilute","offer_id":49735299662064,"sku":"BSB 5015","price":103.0,"currency_code":"USD","in_stock":true},{"title":"BSB 5016,7.0 mL,Predilute","offer_id":49735299694832,"sku":"BSB 5016","price":190.0,"currency_code":"USD","in_stock":true},{"title":"BSB 5017,15.0 mL,Predilute","offer_id":49735299727600,"sku":"BSB 5017","price":339.0,"currency_code":"USD","in_stock":true},{"title":"BSB 5018,0.1 mL,Concentrate","offer_id":49735299760368,"sku":"BSB 5018","price":130.0,"currency_code":"USD","in_stock":true},{"title":"BSB 5019,0.5 mL,Concentrate","offer_id":49735299793136,"sku":"BSB 5019","price":415.0,"currency_code":"USD","in_stock":true},{"title":"BSB 5020,1.0 mL,Concentrate","offer_id":49735299825904,"sku":"BSB 5020","price":743.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0686\/3660\/6704\/files\/PI5020.jpg?v=1778680402"},{"product_id":"pi5027","title":"Actin Muscle Specific","description":"\u003cp\u003eActin is a globular-structural, 345 kDa protein that polymerizes in a helical fashion to form an actin filament (or microfilament). Actin filaments provide mechanical support for the cell, determine the cell shape, enable cell movements (through lamellipodia, filopodia, or pseudopodia); and participate in certain cell junctions, in\n\u003cbr\u003e cytoplasmic streaming and in contraction of the cell during cytokinesis. In muscle cells they play an essential role, along with myosin, in muscle contraction. In the cytosol, actin is predominantly bound to ATP, but can also bind to ADP.\n\u003cbr\u003e \n\u003cbr\u003e This antibody recognizes actin of skeletal, cardiac, and smooth-muscle cells. It is not reactive with other mesenchymal cells except for myoepithelium. Muscle-Specific Actin recognizes alpha and gamma isotypes of all muscle groups. Non-muscle cells such as vascular endothelial cells and connective tissues are nonreactive. Neoplastic cells of non-muscle-derived tissue such as Carcinomas, Melanomas and Lymphomas are negative. This antibody is useful in the identification of rhabdoid cellular elements.\u003c\/p\u003e","brand":"biosb","offers":[{"title":"BSB 5022,3.0 mL,Predilute","offer_id":49735300546800,"sku":"BSB 5022","price":149.0,"currency_code":"USD","in_stock":true},{"title":"BSB 5023,7.0 mL,Predilute","offer_id":49735300579568,"sku":"BSB 5023","price":183.0,"currency_code":"USD","in_stock":true},{"title":"BSB 5024,15.0 mL,Predilute","offer_id":49735300612336,"sku":"BSB 5024","price":344.0,"currency_code":"USD","in_stock":true},{"title":"BSB 5025,0.1 mL,Concentrate","offer_id":49735300645104,"sku":"BSB 5025","price":146.0,"currency_code":"USD","in_stock":true},{"title":"BSB 5026,0.5 mL,Concentrate","offer_id":49735300677872,"sku":"BSB 5026","price":273.0,"currency_code":"USD","in_stock":true},{"title":"BSB 5027,1.0 mL,Concentrate","offer_id":49735300710640,"sku":"BSB 5027","price":368.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0686\/3660\/6704\/files\/PI5027.jpg?v=1778680487"},{"product_id":"pi5034","title":"Actin Smooth Muscle","description":"\u003cp\u003eActin is a major component of the cytoskeleton and is present in every cell type. Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. In vertebrates 3 main groups of actin isoforms (alpha, beta and gamma) have been identified. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins coexist in most cell types as components of the cytoskeleton and as mediators of internal cell motility.\n\u003cbr\u003e \n\u003cbr\u003e Smooth-Muscle Actin antibody does not stain cardiac or skeletal muscle; however, it will stain myofibroblasts and myoepithelial cells. This antibody could be used together with Muscle-Specific Actin to distinguish Leiomyosarcoma from Rhabdomyosarcoma. In most cases of Rhabdomyosarcoma, this antibody gives negative results whereas M. S. Actin is positive in the rhabdomyoblasts. Leiomyosarcomas are positive with both M. S. Actin and S. M. Actin antibodies.\u003c\/p\u003e","brand":"biosb","offers":[{"title":"BSB 5029,3.0 mL,Predilute","offer_id":49735301234928,"sku":"BSB 5029","price":146.0,"currency_code":"USD","in_stock":true},{"title":"BSB 5030,7.0 mL,Predilute","offer_id":49735301267696,"sku":"BSB 5030","price":263.0,"currency_code":"USD","in_stock":true},{"title":"BSB 5031,15.0 mL,Predilute","offer_id":49735301300464,"sku":"BSB 5031","price":473.0,"currency_code":"USD","in_stock":true},{"title":"BSB 5032,0.1 mL,Concentrate","offer_id":49735301333232,"sku":"BSB 5032","price":113.0,"currency_code":"USD","in_stock":true},{"title":"BSB 5033,0.5 mL,Concentrate","offer_id":49735301366000,"sku":"BSB 5033","price":312.0,"currency_code":"USD","in_stock":true},{"title":"BSB 5034,1.0 mL,Concentrate","offer_id":49735301398768,"sku":"BSB 5034","price":598.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0686\/3660\/6704\/files\/PI5034.jpg?v=1778680571"},{"product_id":"pi3251","title":"Adipophilin\/ADRP","description":"\u003cp\u003eAdipose differentiation-related protein, also known as perilipin 2 (PLIN2), ADRP or adipophilin, is a protein which in humans is encoded by the ADFP gene. Adipocyte differentiation-related protein is associated with the globule surface membrane material. This protein is a major constituent of the globule surface. Increase in mRNA levels is one of the earliest indications of adipocyte differentiation. Adipophilin occurs in a wide range of cultured cell lines, including fibroblasts and endothelial and epithelial cells. In tissues, however, expression of adipophilin is restricted to certain cell types, such as lactating mammary epithelial cells, adrenal cortex cells, Sertoli and Leydig cells of the male reproductive system, and steatosis or fatty change hepatocytes in alcoholic liver cirrhosis. \n\u003cbr\u003e \n\u003cbr\u003e Adipophilin expression in various sebaceous lesions and other cutaneous tumors with a clear cell histology that may mimic sebaceous differentiation. Adipophilin can be valuable in an immunohistochemical panel when evaluating cutaneous lesions with clear cell histology as it identifies intracytoplasmic lipid vesicles in sebaceous and xanthomatous lesions. In periocular lesions, it is effective in helping to exclude basal cell carcinoma and squamous cell carcinoma when sebaceous carcinoma is under consideration. Adipophilin expression is not as useful for the differential diagnosis that includes metastatic renal cell carcinoma, a rare but important, diagnostic differential. The pattern of adipophilin reactivity is important to observe as membranous vesicular staining is suggestive of intracellular lipids whereas granular cytoplasmic reactivity is not. Adipophilin is suitable for immunostaining and is helpful in the identification of intracytoplasmic lipids, as seen in sebaceous lesions. It is especially helpful in identifying intracytoplasmic lipid vesicles in poorly differentiated sebaceous carcinomas in challenging cases such as small periocular biopsy specimens.\u003c\/p\u003e","brand":"biosb","offers":[{"title":"BSB 3246,3.0 mL,Predilute","offer_id":49735301890288,"sku":"BSB 3246","price":173.0,"currency_code":"USD","in_stock":true},{"title":"BSB 3247,7.0 mL,Predilute","offer_id":49735301923056,"sku":"BSB 3247","price":434.0,"currency_code":"USD","in_stock":true},{"title":"BSB 3248,15.0 mL,Predilute","offer_id":49735301955824,"sku":"BSB 3248","price":868.0,"currency_code":"USD","in_stock":true},{"title":"BSB 3249,0.1 mL,Concentrate","offer_id":49735301988592,"sku":"BSB 3249","price":145.0,"currency_code":"USD","in_stock":true},{"title":"BSB 3250,0.5 mL,Concentrate","offer_id":49735302021360,"sku":"BSB 3250","price":434.0,"currency_code":"USD","in_stock":true},{"title":"BSB 3251,1.0 mL,Concentrate","offer_id":49735302054128,"sku":"BSB 3251","price":795.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0686\/3660\/6704\/files\/PI3251.jpg?v=1778681748"},{"product_id":"pi3017","title":"Albumin","description":"\u003cp\u003eThe albumins are a family of globular proteins, the most common of which are the serum albumins. Albumins are commonly found in blood plasma and differ from other blood proteins in that they are not glycosylated. Albumin functions primarily as a carrier protein for steroids, fatty acids, and thyroid hormones and plays a role in stabilizing extracellular fluid volume. Mutations in this gene on chromosome 4 result in various anomalous proteins.\n\u003cbr\u003e \n\u003cbr\u003e Low albumin (hypoalbuminemia) may be caused by liver disease, nephrotic syndrome, burns, protein-losing enteropathy, malabsorption, malnutrition, late pregnancy, artefact, genetic variations and malignancy. High albumin (hyperalbuminemia) is almost always caused by dehydration. In some cases of retinol (Vitamin A) deficiency, the albumin level can be elevated to high-normal values.\n\u003cbr\u003e \n\u003cbr\u003e In systemic lupus erythematosus (SLE) patients, reports have been published of an increased prevalence of IgG autoantibodies against human serum albumin (anti-HSA IgG) that are associated with SLE disease activity.\u003c\/p\u003e","brand":"biosb","offers":[{"title":"BSB 3012,3.0 mL,Tinto Predilute","offer_id":49735302414576,"sku":"BSB 3012","price":174.0,"currency_code":"USD","in_stock":true},{"title":"BSB 3013,7.0 mL,Tinto Predilute","offer_id":49735302447344,"sku":"BSB 3013","price":319.0,"currency_code":"USD","in_stock":true},{"title":"BSB 3014,15.0 mL,Tinto Predilute","offer_id":49735302480112,"sku":"BSB 3014","price":572.0,"currency_code":"USD","in_stock":true},{"title":"BSB 3015,,Concentrate","offer_id":49735302512880,"sku":"BSB 3015","price":159.0,"currency_code":"USD","in_stock":true},{"title":"BSB 3016,,Concentrate","offer_id":49735302545648,"sku":"BSB 3016","price":316.0,"currency_code":"USD","in_stock":true},{"title":"BSB 3017,,Concentrate","offer_id":49735302578416,"sku":"BSB 3017","price":628.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0686\/3660\/6704\/files\/PI3017.jpg?v=1778681995"},{"product_id":"pi3000","title":"Albumin\\FITC","description":"\u003cp\u003eThe albumins are a family of globular proteins, the most common of which are the serum albumins. Albumins are commonly found in blood plasma and differ from other blood proteins in that they are not glycosylated. Albumin functions primarily as a carrier protein for steroids, fatty acids, and thyroid hormones and plays a role in stabilizing extracellular fluid volume. Mutations in this gene on chromosome 4 result in various anomalous proteins.\n\u003cbr\u003e \n\u003cbr\u003e Low albumin (hypoalbuminemia) may be caused by liver disease, nephrotic syndrome, burns, protein-losing enteropathy, malabsorption, malnutrition, late pregnancy, artefact, genetic variations and malignancy. High albumin (hyperalbuminemia) is almost always caused by dehydration. In some cases of retinol (Vitamin A) deficiency, the albumin level can be elevated to high-normal values.\n\u003cbr\u003e \n\u003cbr\u003e It has been reported in systemic lupus erythematosus (SLE) patients an increased prevalence of IgG autoantibodies against human serum albumin (anti-HSA IgG) that are associated with SLE disease activity.\u003c\/p\u003e","brand":"biosb","offers":[{"title":"BSB-3000-3,3.0 mL,Tinto Predilute","offer_id":49735302971632,"sku":"BSB-3000-3","price":163.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3000-7,7.0 mL,Tinto Predilute","offer_id":49735303004400,"sku":"BSB-3000-7","price":272.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3000-15,15.0 mL,Tinto Predilute","offer_id":49735303037168,"sku":"BSB-3000-15","price":455.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3000-05,0.5 mL,Concentrate","offer_id":49735303069936,"sku":"BSB-3000-05","price":354.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3000-1,1.0 mL,Concentrate","offer_id":49735303102704,"sku":"BSB-3000-1","price":590.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0686\/3660\/6704\/files\/PI3000.jpg?v=1778682101"},{"product_id":"pi2801","title":"ALK-1\/CD246","description":"\u003cp\u003eAnaplastic Lymphoma Kinase (ALK) was originally discovered as a NPM (Nucleophosmin)-ALK fusion protein. The ALK gene is on chromosome 2. Upon translocation between chromosome 2 and chromosome 5 t(2;5), the ALK gene fuses with the NPM gene. The chimeric product (NPM ALK) resulting from t(2;5) translocation is a protein of 80 kDa with the N terminal portion of NPM linked to the complete intracellular portion of ALK.\n\u003cbr\u003e \n\u003cbr\u003e This antibody recognizes a human p80 protein, identified as a hybrid of the Anaplastic Lymphoma Kinase (ALK) gene and the Nucleophosmin (NPM) gene resulting from the t(2;5)(p23;q35) translocation found in a third of Large-Cell Lymphomas. ALK-1 is detected in 60% of Anaplastic Large-Cell Lymphomas and has proven to indicate a better prognosis in the ALK-1 (+) group.\u003c\/p\u003e","brand":"biosb","offers":[{"title":"BSB 2796,3.0 mL,Predilute","offer_id":49735303495920,"sku":"BSB 2796","price":330.0,"currency_code":"USD","in_stock":true},{"title":"BSB 2797,7.0 mL,Predilute","offer_id":49735303528688,"sku":"BSB 2797","price":604.0,"currency_code":"USD","in_stock":true},{"title":"BSB 2798,15.0 mL,Predilute","offer_id":49735303561456,"sku":"BSB 2798","price":1084.0,"currency_code":"USD","in_stock":true},{"title":"BSB 2799,0.1 mL,Concentrate","offer_id":49735303594224,"sku":"BSB 2799","price":330.0,"currency_code":"USD","in_stock":true},{"title":"BSB 2800,0.5 mL,Concentrate","offer_id":49735303626992,"sku":"BSB 2800","price":814.0,"currency_code":"USD","in_stock":true},{"title":"BSB 2801,1.0 mL,Concentrate","offer_id":49735303659760,"sku":"BSB 2801","price":1238.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0686\/3660\/6704\/files\/PI2801.jpg?v=1778682221"},{"product_id":"pi5048","title":"ALK-1\\CD246","description":"\u003cp\u003eAnaplastic Lymphoma Kinase (ALK) was originally discovered as a NPM (Nucleophosmin)-ALK fusion protein. The ALK gene is on chromosome 2. Upon translocation between chromosome 2 and chromosome 5 t(2;5), the ALK gene fuses with the NPM gene. The chimeric product (NPM ALK) resulting from t(2;5) translocation is a protein of 80 kDa with the N terminal portion of NPM linked to the complete intracellular portion of ALK.\n\u003cbr\u003e \n\u003cbr\u003e This antibody recognizes a human p80 protein, identified as a hybrid of the Anaplastic Lymphoma Kinase (ALK) gene and the Nucleophosmin (NPM) gene resulting from the t(2;5)(p23;q35) translocation found in a third of Large-Cell Lymphomas. ALK-1 is detected in 60% of Anaplastic Large-Cell Lymphomas and has proven to indicate a better prognosis in the ALK-1 (+) group.\u003c\/p\u003e","brand":"biosb","offers":[{"title":"BSB 5043,3.0 mL,Predilute","offer_id":49735304151280,"sku":"BSB 5043","price":277.0,"currency_code":"USD","in_stock":true},{"title":"BSB 5044,7.0 mL,Predilute","offer_id":49735304184048,"sku":"BSB 5044","price":502.0,"currency_code":"USD","in_stock":true},{"title":"BSB 5045,15.0 mL,Predilute","offer_id":49735304216816,"sku":"BSB 5045","price":907.0,"currency_code":"USD","in_stock":true},{"title":"BSB 5046,0.1 mL,Concentrate","offer_id":49735304249584,"sku":"BSB 5046","price":310.0,"currency_code":"USD","in_stock":true},{"title":"BSB 5047,0.5 mL,Concentrate","offer_id":49735304282352,"sku":"BSB 5047","price":681.0,"currency_code":"USD","in_stock":true},{"title":"BSB 5048,1.0 mL,Concentrate","offer_id":49735304315120,"sku":"BSB 5048","price":1042.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0686\/3660\/6704\/files\/PI5048.jpg?v=1778682300"},{"product_id":"pi3291","title":"Alpha Synuclein","description":"\u003cp\u003eAlpha-synuclein is a 140 amino acids protein encoded by the SNCA gene. It is predominantly expressed in the neocortex, hippocampus, substantia nigra, thalamus, and cerebellum with smaller amounts found in the heart, muscles, and other tissues. In the brain, alpha-synuclein is found mainly in presynaptic terminals. \n\u003cbr\u003e \n\u003cbr\u003e An alpha-synuclein fragment, known as the non-Abeta component (NAC) of Alzheimer’s disease amyloid, originally found in an amyloid-enriched fraction, was shown to be a fragment of its precursor protein, NACP. Alpha-synuclein aggregates to form insoluble fibrils in pathological conditions characterized by Lewy bodies, such as Parkinson’s disease, dementia with Lewy bodies and multiple system atrophy. These disorders are known as synucleinopathies. Occasionally, Lewy bodies contain tau protein; however, alpha-synuclein and tau constitute two distinctive subsets of filaments in the same inclusion bodies.\n\u003cbr\u003e \n\u003cbr\u003e Alpha-synuclein pathology is also found in both sporadic and familial cases with Alzheimer’s disease. In rare cases of familial forms of Parkinson’s disease, there is a mutation in the gene coding for alpha-synuclein. Genomic duplication and triplication of the gene appear to be a rare cause of Parkinson’s disease in other lineages, although more common than point mutations. Hence certain mutations of alpha-synuclein may cause it to form amyloid-like fibrils that contribute to Parkinson’s disease.\u003c\/p\u003e","brand":"biosb","offers":[{"title":"BSB 3286,3.0 mL,Predilute","offer_id":49735304806640,"sku":"BSB 3286","price":181.0,"currency_code":"USD","in_stock":true},{"title":"BSB 3287,7.0 mL,Predilute","offer_id":49735304839408,"sku":"BSB 3287","price":327.0,"currency_code":"USD","in_stock":true},{"title":"BSB 3288,15.0 mL,Predilute","offer_id":49735304872176,"sku":"BSB 3288","price":591.0,"currency_code":"USD","in_stock":true},{"title":"BSB 3289,0.1 mL,Concentrate","offer_id":49735304904944,"sku":"BSB 3289","price":165.0,"currency_code":"USD","in_stock":true},{"title":"BSB 3290,0.5 mL,Concentrate","offer_id":49735304937712,"sku":"BSB 3290","price":423.0,"currency_code":"USD","in_stock":true},{"title":"BSB 3291,1.0 mL,Concentrate","offer_id":49735304970480,"sku":"BSB 3291","price":721.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0686\/3660\/6704\/files\/PI3291.jpg?v=1778682535"},{"product_id":"pi5055","title":"Alpha-Fetoprotein","description":"\u003cp\u003eAlpha-fetoprotein (AFP) is a protein which in humans is encoded by the AFP gene. This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. This protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem on chromosome 4.\n\u003cbr\u003e \n\u003cbr\u003e Positive staining with this antibody is seen in hepatocytes of fetal liver and hepatoma. Since only traces of AFP are found in adult serum, elevated levels suggest either a benign or malignant lesion of the liver, a Yolk-Sac Carcinoma, or one of a few other tumors. In conjunction with elevated serum levels, AFP has been immunohistochemically demonstrated in Yolk-Sac Carcinomas in gonadal and extragonadal sites of hepatic malignancies and a few other neoplasms.\u003c\/p\u003e","brand":"biosb","offers":[{"title":"BSB 5050,3.0 mL,Predilute","offer_id":49735305560304,"sku":"BSB 5050","price":110.0,"currency_code":"USD","in_stock":true},{"title":"BSB 5051,7.0 mL,Predilute","offer_id":49735305593072,"sku":"BSB 5051","price":190.0,"currency_code":"USD","in_stock":true},{"title":"BSB 5052,15.0 mL,Predilute","offer_id":49735305625840,"sku":"BSB 5052","price":339.0,"currency_code":"USD","in_stock":true},{"title":"BSB 5053,0.1 mL,Concentrate","offer_id":49735305658608,"sku":"BSB 5053","price":130.0,"currency_code":"USD","in_stock":true},{"title":"BSB 5054,0.5 mL,Concentrate","offer_id":49735305691376,"sku":"BSB 5054","price":166.0,"currency_code":"USD","in_stock":true},{"title":"BSB 5055,1.0 mL,Concentrate","offer_id":49735305724144,"sku":"BSB 5055","price":227.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0686\/3660\/6704\/files\/PI5055.jpg?v=1778682759"},{"product_id":"pi5062","title":"AMACRacemase\/P504S","description":"\u003cp\u003eAMACR (P504S) is an acronym for the protein alpha-methylacyl CoA racemase that helps to metabolize certain fatty acids within the body. AMACR has been recently described as a prostate cancer-specific gene that encodes a protein involved in the beta-oxidation of branched chain fatty acids. Expression of AMACR protein is found in Prostatic Adenocarcinoma but not in benign prostatic tissue. It stains premalignant lesions of the prostate: High-Grade Prostatic Intraepithelial Neoplasia (PIN) and Atypical Adenomatous Hyperplasia. Several studies have suggested that AMACR can be used as a prostate cancer biomarker.\n\u003cbr\u003e \n\u003cbr\u003e High expression of AMACR (P504S) protein is usually found in Prostatic Adenocarcinoma but not in benign prostatic tissue by immunohistochemical staining in paraffin-embedded tissues. Using AMACR as a positive marker along with basal-cell staining (34βE12 or p63) as a negative marker could help to confirm the diagnosis of small foci of Prostate Carcinoma on needle biopsies.\u003c\/p\u003e","brand":"biosb","offers":[{"title":"BSB 5057,3.0 mL,Predilute","offer_id":49735306248432,"sku":"BSB 5057","price":246.0,"currency_code":"USD","in_stock":true},{"title":"BSB 5058,7.0 mL,Predilute","offer_id":49735306281200,"sku":"BSB 5058","price":408.0,"currency_code":"USD","in_stock":true},{"title":"BSB 5059,15.0 mL,Predilute","offer_id":49735306313968,"sku":"BSB 5059","price":737.0,"currency_code":"USD","in_stock":true},{"title":"BSB 5060,0.1 mL,Concentrate","offer_id":49735306346736,"sku":"BSB 5060","price":252.0,"currency_code":"USD","in_stock":true},{"title":"BSB 5061,0.5 mL,Concentrate","offer_id":49735306379504,"sku":"BSB 5061","price":575.0,"currency_code":"USD","in_stock":true},{"title":"BSB 5062,1.0 mL,Concentrate","offer_id":49735306412272,"sku":"BSB 5062","price":876.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0686\/3660\/6704\/files\/PI5062.jpg?v=1778682834"},{"product_id":"pi2808","title":"Amyloid A","description":"\u003cp\u003eSerum amyloid A (SAA) proteins are a family of apolipoproteins associated with high-density lipoprotein (HDL) in plasma. Different isoforms of SAA are expressed constitutively (constitutive SAAs) at different levels or in response to inflammatory stimuli (acute phase SAAs). These proteins are produced predominantly by the liver. The conservation of these proteins throughout invertebrates and vertebrates suggests that SAAs play a highly essential role in all animals. Acute-phase serum amyloid A proteins (A-SAAs) are secreted during the acute phase of inflammation. These proteins have several roles, including the transport of cholesterol to the liver for secretion into the bile, the recruitment of immune cells to inflammatory sites, and the induction of enzymes that degrade extracellular matrix. A-SAAs are implicated in several chronic inflammatory diseases, such as amyloidosis, atherosclerosis, and rheumatoid arthritis.\n\u003cbr\u003e \n\u003cbr\u003e Amyloidosis is a disease characterized by the abnormal build-up of amyloid, abnormal non-branching fibrillary β-pleated sheet proteins that are insoluble and highly resistant to proteolytic degradation that result in localized or systemic organ dysfunction. Amyloidosis are grouped as AL (primary), AA (secondary), and hereditary forms. Proper classification is important since treatment and prognosis of the disorders are vastly different. AA amyloidosis is associated with a variety of chronic inflammatory conditions and infections, derived from SAA. Immunohistochemical staining using a panel of antibodies including κ and λ Ig light chains, Amyloid A, and Transthyretin can aid in recognizing most forms of amyloid. The Amyloid A immunostaining detects tissue deposition of serum Amyloid A protein, an acute phase reactive protein. It is positive in AA Amyloidosis and familial Mediterranean fever. Recently, SAA has also been investigated as a potential marker for neoplastic activity. SAA concentrations have been reported to be a marker of poor prognosis, elevated in patients with advanced stages of cancer and those with malignant disease.\u003c\/p\u003e","brand":"biosb","offers":[{"title":"BSB 2803,3.0 mL,Tinto Predilute","offer_id":49735307165936,"sku":"BSB 2803","price":225.0,"currency_code":"USD","in_stock":true},{"title":"BSB 2804,7.0 mL,Tinto Predilute","offer_id":49735307198704,"sku":"BSB 2804","price":375.0,"currency_code":"USD","in_stock":true},{"title":"BSB 2805,15.0 mL,Tinto Predilute","offer_id":49735307231472,"sku":"BSB 2805","price":753.0,"currency_code":"USD","in_stock":true},{"title":"BSB 2806,0.1 mL,Concentrate","offer_id":49735307264240,"sku":"BSB 2806","price":195.0,"currency_code":"USD","in_stock":true},{"title":"BSB 2807,0.5 mL,Concentrate","offer_id":49735307297008,"sku":"BSB 2807","price":595.0,"currency_code":"USD","in_stock":true},{"title":"BSB 2808,1.0 mL,Concentrate","offer_id":49735307329776,"sku":"BSB 2808","price":1121.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0686\/3660\/6704\/files\/PI2808.jpg?v=1778682892"},{"product_id":"pi3446","title":"Amyloid Beta","description":"\u003cp\u003eAmyloid beta (Aβ or Abeta) consists of peptides of 36–43 amino acids that are crucially involved in Alzheimer’s disease as the main component of the amyloid plaques found in the brains of Alzheimer patients. The peptides result from the amyloid precursor protein (APP). Amyloid beta circulates in plasma, cerebrospinal fluid (CSF) and brain interstitial fluid (ISF) mainly as soluble Aβ40. Amyloid beta is the main constituent of brain parenchyma and vascular amyloid; it contributes to cerebrovascular lesions and is neurotoxic. \n\u003cbr\u003e \n\u003cbr\u003e Brain Amyloid beta is elevated in patients with sporadic Alzheimer’s disease and is the main component of amyloid plaques. Similar plaques appear in some variants of Lewy body dementia and in inclusion body myositis, while Amyloid beta can also form the aggregates that coat cerebral blood vessels in cerebral amyloid angiopathy. The plaques are composed of a tangle of regularly ordered fibrillar aggregates called amyloid fibers, a protein fold shared by other peptides such as the prions associated with protein misfolding diseases. \n\u003cbr\u003e \n\u003cbr\u003e The mechanism by which Amyloid beta may damage and kill neurons is by generating reactive oxygen species during the process of its self-aggregation. It has been reported that amyloid beta production follows a circadian rhythm, rising when an animal or a person is awake and falling during sleep. The wakefulness-promoting neuroprotein orexin has been shown to be necessary for the circadian rhythm of amyloid beta production. This is consistent with recent findings that chronic sleep deprivation is associated with early onset Alzheimer’s disease.\u003c\/p\u003e","brand":"biosb","offers":[{"title":"BSB 3441,3.0 mL,Predilute","offer_id":49735307854064,"sku":"BSB 3441","price":219.0,"currency_code":"USD","in_stock":true},{"title":"BSB 3442,7.0 mL,Predilute","offer_id":49735307886832,"sku":"BSB 3442","price":367.0,"currency_code":"USD","in_stock":true},{"title":"BSB 3443,15.0 mL,Predilute","offer_id":49735307919600,"sku":"BSB 3443","price":736.0,"currency_code":"USD","in_stock":true},{"title":"BSB 3444,0.1 mL,Concentrate","offer_id":49735307952368,"sku":"BSB 3444","price":207.0,"currency_code":"USD","in_stock":true},{"title":"BSB 3445,0.5 mL,Concentrate","offer_id":49735307985136,"sku":"BSB 3445","price":634.0,"currency_code":"USD","in_stock":true},{"title":"BSB 3446,1.0 mL,Concentrate","offer_id":49735308017904,"sku":"BSB 3446","price":1119.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0686\/3660\/6704\/files\/PI3446.jpg?v=1778683134"},{"product_id":"pi6076","title":"Androgen Receptor","description":"\u003cp\u003eThe androgen receptor (AR) is a type of nuclear receptor which is activated by binding of either of the androgenic hormones testosterone or dihydrotestosterone. The main function of the androgen receptor is as a DNA-binding transcription factor which regulates gene expression. However, the androgen receptor has additional functions independent of DNA binding. The AR signaling pathway plays a key role in development and function of male reproductive organs, including the prostate and epididymis. AR also plays a role in nonreproductive organs, such as muscle, hair follicles, and the brain.\n\u003cbr\u003e \n\u003cbr\u003e This antibody reacts with the androgen receptor and also with the newly-described A form of the receptor. This antibody does not cross-react with estrogen, progesterone or glucocorticoid receptors. Abnormalities in the AR-signaling pathway have been linked to a number of diseases, including Prostate Cancer, Kennedy’s Disease and male infertility.\u003c\/p\u003e","brand":"biosb","offers":[{"title":"BSB 6071,3.0 mL,Predilute","offer_id":49735308312816,"sku":"BSB 6071","price":166.0,"currency_code":"USD","in_stock":true},{"title":"BSB 6072,7.0 mL,Predilute","offer_id":49735308345584,"sku":"BSB 6072","price":301.0,"currency_code":"USD","in_stock":true},{"title":"BSB 6073,15.0 mL,Predilute","offer_id":49735308378352,"sku":"BSB 6073","price":544.0,"currency_code":"USD","in_stock":true},{"title":"BSB 6074,0.1 mL,Concentrate","offer_id":49735308411120,"sku":"BSB 6074","price":164.0,"currency_code":"USD","in_stock":true},{"title":"BSB 6075,0.5 mL,Concentrate","offer_id":49735308443888,"sku":"BSB 6075","price":415.0,"currency_code":"USD","in_stock":true},{"title":"BSB 6076,1.0 mL,Concentrate","offer_id":49735308476656,"sku":"BSB 6076","price":790.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0686\/3660\/6704\/files\/PI6076.jpg?v=1778683201"},{"product_id":"pi6364","title":"Annexin A1","description":"\u003cp\u003eThe protein Annexin A1 is encoded by the ANXA1 gene, which is upregulated in hairy cell leukemia. The NFkB signal transduction pathway is exploited by cancerous cells to proliferate and avoid apoptosis. Annexin A1 inhibits that pathway by binding to the p65 subunit, thus making Annexin A1 of particular interest for use as a potential anti-cancer drug. It may also contain tumor suppressive and protective characteristics, as has been evidenced by its ability to protect against DNA damage induced by heat in breast cancer cells.\n\u003cbr\u003e \n\u003cbr\u003e Annexin A1 is strongly expressed on the cell membrane and occasionally in the cytoplasm of tumor cells in 97% of samples from patients with hairy cell leukemia. By contrast, B-cell lymphomas other than hairy cell leukemia are ANXA1 negative. Thus, ANXA1 is a molecule specific to hairy cell leukemia that can be used to differentiate this disease from other B-cell lymphomas.\u003c\/p\u003e","brand":"biosb","offers":[{"title":"BSB 6359,3.0 mL,Predilute","offer_id":49735308509424,"sku":"BSB 6359","price":157.0,"currency_code":"USD","in_stock":true},{"title":"BSB 6360,7.0 mL,Predilute","offer_id":49735308542192,"sku":"BSB 6360","price":290.0,"currency_code":"USD","in_stock":true},{"title":"BSB 6361,15.0 mL,Predilute","offer_id":49735308574960,"sku":"BSB 6361","price":518.0,"currency_code":"USD","in_stock":true},{"title":"BSB 6362,0.1 mL,Concentrate","offer_id":49735308607728,"sku":"BSB 6362","price":149.0,"currency_code":"USD","in_stock":true},{"title":"BSB 6363,0.5 mL,Concentrate","offer_id":49735308640496,"sku":"BSB 6363","price":246.0,"currency_code":"USD","in_stock":true},{"title":"BSB 6364,1.0 mL,Concentrate","offer_id":49735308673264,"sku":"BSB 6364","price":450.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0686\/3660\/6704\/files\/PI6364.jpg?v=1778683268"},{"product_id":"pi3709","title":"Annexin VII","description":"\u003cp\u003eAnnexin VII (or Annexin A7) is a Ca2+-dependent and phospholipid-binding protein. It is encoded by the ANX7 gene, which is located in human chromosome 10q21. It is a member of the annexin protein family, which regulates various endomembrane processes including vesicle fusion, segregation, and compartmentalization and is implicated in plasma membrane repair mechanisms.\n\u003cbr\u003e \n\u003cbr\u003e Studies suggest that ANX7 is a tumor suppressor gene and it was found that Annexin VII is associated with several types of cancers, such as Prostate, Breast, Liver, and Gastric cancer. IHC analysis showed that a low or the loss of expression of ANX7 correlates with Prostate cancer progression. On the contrary, high levels of ANX7 expression were found in Metastatic Breast Tumors and that HER2-Negative patients suffer increased risk of death when ANX7 expression levels are elevated. Another study found that ANX7 predominantly shows low expression in other cancer types, such as Colon Adenocarcinoma or Bladder Transitional Cell Carcinoma. A study identified the prognostic impact of ANXA7 in Prostate Cancer using tissue microarrays, identified ANXA7 as a new prognostic factor and indicated a bimodal correlation to tumor progression. Another study concluded that Annexin A7 expression was able to inhibit HCC lymph node metastasis, whereas knockdown of Annexin A7 expression significantly induced HCC metastasis to local lymph nodes.\u003c\/p\u003e","brand":"biosb","offers":[{"title":"BSB-3709-3,3.0 mL,Predilute","offer_id":49735308706032,"sku":"BSB-3709-3","price":255.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3709-7,7.0 mL,Predilute","offer_id":49735308738800,"sku":"BSB-3709-7","price":455.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3709-15,15.0 mL,Predilute","offer_id":49735308771568,"sku":"BSB-3709-15","price":802.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3709-01,0.1 mL,Concentrate","offer_id":49735308804336,"sku":"BSB-3709-01","price":264.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3709-05,0.5 mL,Concentrate","offer_id":49735308837104,"sku":"BSB-3709-05","price":574.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3709-1,1.0 mL,Concentrate","offer_id":49735308869872,"sku":"BSB-3709-1","price":912.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0686\/3660\/6704\/files\/PI3709.jpg?v=1778683356"},{"product_id":"pi3798","title":"APOE4","description":"\u003cp\u003eApolipoprotein E4 (APOE4) is a protein known to contribute to the onset of Alzheimer’s disease. While it is expressed in many organs, in the brain APOE4 has been associated with deposition of insoluble amyloid plaques Aβ40 and Aβ42 in the interstitial fluid in the cortex and hippocampus. APOE isoforms are produced by astrocyte cells, and assist in the delivery of lipids such as cholesterol to the neurons. LDL receptor-related protein 1 (LRP1) metabolizes APOE and Aβ plaques; in knockout mice models, the presence of APOE4 (more than other isoforms) was shown to increase the deposition of insoluble Aβ40 and Aβ42 in the presence of LRP1. \n\u003cbr\u003e APOE4 has been found to be a genetic factor in the pathology of Alzheimer’s disease, Lewy Body Dementia, and Parkinson’s Disease. The mechanisms of overproduction of plaques and interference in clearing the amyloid peptides result in the accumulation of Aβ42. The Aβ plaque burden in the brains of Alzheimer’s patients with APOE4 isoform is around 2.7 times that of patients with APOE3 isoform, indicating a role of APOE4 in Aβ metabolism. The accumulated Aβ oligomers have been shown to disrupt synaptic function- the loss of dendritic spines contributes to the loss of cognitive function. APOE4 has also been shown to predict better prognosis than APOE2 isotype in melanoma patients, but overall APOE serum levels predict immunosuppression and worse patient survival in Pancreatic Ductal Cell Carcinoma.\u003c\/p\u003e","brand":"biosb","offers":[{"title":"BSB-3798-3,3.0 mL,Predilute","offer_id":49735309099248,"sku":"BSB-3798-3","price":231.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3798-7,7.0 mL,Predilute","offer_id":49735309132016,"sku":"BSB-3798-7","price":347.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3798-15,15.0 mL,Predilute","offer_id":49735309164784,"sku":"BSB-3798-15","price":580.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3798-01,0.1 mL,Concentrate","offer_id":49735309197552,"sku":"BSB-3798-01","price":231.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3798-05,0.5 mL,Concentrate","offer_id":49735309230320,"sku":"BSB-3798-05","price":464.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3798-1,1.0 mL,Concentrate","offer_id":49735309263088,"sku":"BSB-3798-1","price":811.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0686\/3660\/6704\/files\/PI3798.jpg?v=1778683412"},{"product_id":"pi2452","title":"Arginase-1","description":"\u003cp\u003eArginase-1 is the catalyst for the fifth and final step in the urea cycle, which is a series of biochemical reactions in mammals during which the body disposes of harmful ammonia. Arginase-1 works to convert L-arginine into L-ornithine and urea. Arginise-1 is located primarily in the cytoplasm of the liver. Arginase-1\n\u003cbr\u003e consists of three tetramers, and the enzyme requires a two-molecule metal cluster of manganese in order to maintain proper function. These Mn2+ ions coordinate with water, orienting and stabilizing the molecule and allowing water to act as a nucelophile and attack L-arginine, hydrolyzing it into ornithine and urea.\n\u003cbr\u003e \n\u003cbr\u003e Arginase-1 is abundantly expressed in the liver and it represents a sensitive and specific marker of benign and malignant hepatocytes. In sections of normal liver, anti-arginase 1 produces strong, diffuse cytoplasmic reactivity in all hepatocytes throughout the lobule. In a small percentage of cases, patchy nuclear reactivity\n\u003cbr\u003e is also evident in hepatocytes along with the strong cytoplasmic reactivity. Hepatocellular carcinoma usually shows higher protein expression of ARG1 than normal liver cells.\u003c\/p\u003e","brand":"biosb","offers":[{"title":"BSB 2447,3.0 mL,Predilute","offer_id":49735309295856,"sku":"BSB 2447","price":248.0,"currency_code":"USD","in_stock":true},{"title":"BSB 2448,7.0 mL,Predilute","offer_id":49735309328624,"sku":"BSB 2448","price":413.0,"currency_code":"USD","in_stock":true},{"title":"BSB 2449,15.0 mL,Predilute","offer_id":49735309361392,"sku":"BSB 2449","price":827.0,"currency_code":"USD","in_stock":true},{"title":"BSB 2450,0.1 mL,Concentrate","offer_id":49735309394160,"sku":"BSB 2450","price":182.0,"currency_code":"USD","in_stock":true},{"title":"BSB 2451,0.5 mL,Concentrate","offer_id":49735309426928,"sku":"BSB 2451","price":612.0,"currency_code":"USD","in_stock":true},{"title":"BSB 2452,1.0 mL,Concentrate","offer_id":49735309459696,"sku":"BSB 2452","price":1210.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0686\/3660\/6704\/files\/PI2452.jpg?v=1778683474"},{"product_id":"pi3749","title":"ARID1A","description":"\u003cp\u003eGenes encoding subunits of SWItch\/sucrose nonfermentable (SWI\/SNF) chromatin remodeling complexes are collectively mutated in 20% of all human cancers. ARID1A is the SWI\/SNF subunit gene that is most frequently mutated, at variable frequencies across molecular and histological subtypes of cancer. \n\u003cbr\u003e \n\u003cbr\u003e ARID1A is a tumour suppressor gene frequently mutated in Clear Cell and Endometrioid Carcinomas of the Ovary and Endometrium. Loss of ARID1A function as shown by loss of expression, presumably due to mutations, is an early molecular event, occurring before malignant transformation, in the development of the majority of Ovarian Clear Cell and Endometrioid Carcinomas arising in Endometriomas. A study found 21 ARID1A mutations were identified in 14\/43 assessable tumours (33%), the majority of which were predicted to be deleterious. Mutations were identified in 6\/17 (35%) Ovarian Clear Cell Carcinomas, 5\/8 (63%) Ovarian Endometrioid Carcinomas, 2\/5 (40%) Endometrial Carcinomas, and 1\/7 (14%) Carcinosarcomas. Some studies have demonstrated that ARID1A has a critical tumor suppressor role in the Colon, and that its inactivation leads to the development of Colon Cancers via a mechanism that is distinct from previously established genetic models. ARID1A inactivating mutations are present at a high frequency in advanced endocrine-resistant ER+ Breast Cancer. ARID1A may play an important role in and serves as a valuable prognostic marker in Gastric Cancer.\u003c\/p\u003e","brand":"biosb","offers":[{"title":"BSB-3749-3,3.0 mL,Predilute","offer_id":49735309492464,"sku":"BSB-3749-3","price":255.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3749-7,7.0 mL,Predilute","offer_id":49735309525232,"sku":"BSB-3749-7","price":455.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3749-15,15.0 mL,Predilute","offer_id":49735309558000,"sku":"BSB-3749-15","price":802.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3749-01,0.1 mL,Concentrate","offer_id":49735309590768,"sku":"BSB-3749-01","price":264.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3749-05,0.5 mL,Concentrate","offer_id":49735309623536,"sku":"BSB-3749-05","price":574.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3749-1,1.0 mL,Concentrate","offer_id":49735309656304,"sku":"BSB-3749-1","price":912.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0686\/3660\/6704\/files\/PI3749.jpg?v=1778683559"},{"product_id":"pi3804","title":"Aspergillus","description":"\u003cp\u003eAspergillus fumigatus and Aspergillus flavus are two common filamentous fungi that cause allergic reactions and Invasive Aspergillosis (IA). The conidia phase can cause fungal infection in the lungs or sinuses of immunocompromised patients who inhale the airborne spores. The spores then produce hyphae in Invasive Pulmonary Aspergillosis (IPA). The Aspergillus hyphae spread locally and can cross into blood vessels to spread to other organs, including the brain, skin, liver, and spleen. \n\u003cbr\u003e In the lungs, Aspergillus hyphae cause bronchiolytic lesions, pneumonia, edema, inflammation, and granulomas with necrotic centers. The necrotic centers may contain fungal fragments, also found in pulmonary macrophages. Thrombosis and platelet activation can help prevent the spread of hyphae, though immunocompromised patients are less able to stop the infection. Invasive aspergillosis has an 85% mortality rate; it is often not even discovered until the autopsy, when tissue can be fixed and examined by IHC (Aspergillus is not grown easily from blood cultures). Diagnosis is further complicated by the lack of distinguishing morphological features- infections by Fusarium species, Scedosporium species, and Pseudallescheria boydii cause similar morphological features and may require IHC to make the correct diagnosis.\u003c\/p\u003e","brand":"biosb","offers":[{"title":"BSB-3804-3-ASR,3.0 mL,Predilute","offer_id":50321127276784,"sku":"BSB-3804-3-ASR","price":242.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3804-7-ASR,7.0 mL,Predilute","offer_id":50321127309552,"sku":"BSB-3804-7-ASR","price":364.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3804-15-ASR,15.0 mL,Predilute","offer_id":50321127342320,"sku":"BSB-3804-15-ASR","price":608.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3804-01-ASR,0.1 mL,Concentrate","offer_id":50321127375088,"sku":"BSB-3804-01-ASR","price":242.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3804-05-ASR,0.5 mL,Concentrate","offer_id":50321127407856,"sku":"BSB-3804-05-ASR","price":486.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3804-1-ASR,1.0 mL,Concentrate","offer_id":50321127440624,"sku":"BSB-3804-1-ASR","price":850.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0686\/3660\/6704\/files\/PI3804.jpg?v=1778683640"},{"product_id":"pi3710","title":"ATM","description":"\u003cp\u003eAtaxia telangiectasia mutated (ATM) protein is a serine\/threonine kinase that belongs to the family of phosphatidylinositol-3 kinase (PI3K)- related protein kinases. ATM is a key checkpoint protein of the DNA damage response pathway. When DNA double-strand breaks occur, ATM activates different cascades, resulting in activation of cell cycle checkpoints, cell cycle arrests, and apoptosis.\n\u003cbr\u003e \n\u003cbr\u003e Mutations in the ATM gene lead to an increased risk of several cancer types, which include Leukemias, Lymphomas, Colorectal Cancer, Pancreatic Cancer and Adenocarcinoma of the Stomach. Studies show that Gastric Cancer tissues were found to be ATM-negative by IHC staining, indicating that ATM can be used as a biomarker. It has also been found that low expression of the ATM protein contributes to more aggressive progression and poor clinical outcome of Breast Cancer. Results of another study indicate loss of ATM protein expression is associated with development of Lung Cancer.\u003c\/p\u003e","brand":"biosb","offers":[{"title":"BSB-3710-3,3.0 mL,Predilute","offer_id":49735310082288,"sku":"BSB-3710-3","price":255.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3710-7,7.0 mL,Predilute","offer_id":49735310115056,"sku":"BSB-3710-7","price":455.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3710-15,15.0 mL,Predilute","offer_id":49735310147824,"sku":"BSB-3710-15","price":802.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3710-01,0.1 mL,Concentrate","offer_id":49735310180592,"sku":"BSB-3710-01","price":264.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3710-05,0.5 mL,Concentrate","offer_id":49735310213360,"sku":"BSB-3710-05","price":574.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3710-1,1.0 mL,Concentrate","offer_id":49735310246128,"sku":"BSB-3710-1","price":912.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0686\/3660\/6704\/files\/PI3710.jpg?v=1778683697"},{"product_id":"pi3711","title":"ATRX","description":"\u003cp\u003eα-thalassemia\/mental retardation syndrome X-linked (ATRX) gene is located on chromosome Xq21.1. ATRX is involved in many fundamental cellular processes such as transcription, replication, DNA repair and recombination. Germline mutations of ATRX have been found to cause the complex genetic disorder called Alpha-Thalassemia mental retardation syndrome. Somatic mutations, deletions, and altered ATRX expression levels were found to be prevalent in several cancer types. A study reported the loss of ATRX expression was found to be a prognostic marker for chromosome instability in pancreatic neuroendocrine tumors. There is also evidence that highlights the role of ATRX as a biomarker in breast cancer in which ATRX expression was significantly associated with tumor grade.\n\u003cbr\u003e \n\u003cbr\u003e Mutation\/loss of ATRX expression has been described in anaplastic gliomas. A study explored the role of ATRX status in the molecular classification of anaplastic gliomas and its impact on survival. Loss of ATRX expression was detected in 45 % of anaplastic astrocytomas (AA), 27 % of anaplastic oligoastrocytomas (AOA) and 10 % of anaplastic oligodendrogliomas (AO). Survival analysis showed a marked separation of IDH mutant astrocytic tumors into two groups based on ATRX status: tumors with ATRX loss had a significantly better prognosis. Another recent study analyzed the use of ATRX, IDH and 1p\/19q codeletion in a series of astrocytomas, oligodendrogliomas, oligoastrocytomas and glioblastomas and presented an algorithm based on stepwise analysis with initial immunohistochemistry for ATRX and IDH1-R132H followed by 1p\/19q analysis, then by IDH sequencing, which reduces the number of molecular analyses and has a far better association with patient outcome.\u003c\/p\u003e","brand":"biosb","offers":[{"title":"BSB-3711-3,3.0 mL,Predilute","offer_id":49735310311664,"sku":"BSB-3711-3","price":250.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3711-7,7.0 mL,Predilute","offer_id":49735310344432,"sku":"BSB-3711-7","price":445.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3711-15,15.0 mL,Predilute","offer_id":49735310377200,"sku":"BSB-3711-15","price":784.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3711-01,0.1 mL,Concentrate","offer_id":49735310409968,"sku":"BSB-3711-01","price":258.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3711-05,0.5 mL,Concentrate","offer_id":49735310442736,"sku":"BSB-3711-05","price":561.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3711-1,1.0 mL,Concentrate","offer_id":49735310475504,"sku":"BSB-3711-1","price":893.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0686\/3660\/6704\/files\/PI3711.jpg?v=1778683797"},{"product_id":"pi3298","title":"ATRX","description":"\u003cp\u003eATRX is also known as ATP-dependent helicase ATRX, X-linked helicase II, or X-linked nuclear protein (XNP) is a protein that in humans is encoded by the ATRX gene. Mutations of the ATRX gene are associated with an X-linked mental retardation (XLMR) syndrome most often accompanied by alpha-thalassemia (ATRX) syndrome. \n\u003cbr\u003e \n\u003cbr\u003e Mutation\/loss of ATRX expression has been described in anaplastic gliomas. A study explored the role of ATRX status in the molecular classification of anaplastic gliomas and its impact on survival. Loss of ATRX expression was detected in 45 % of anaplastic astrocytomas (AA), 27 % of anaplastic oligoastrocytomas (AOA) and 10 % of anaplastic oligodendrogliomas (AO). Survival analysis showed a marked separation of IDH mutant astrocytic tumors into two groups based on ATRX status: tumors with ATRX loss had a significantly better prognosis. \n\u003cbr\u003e \n\u003cbr\u003e Another study conducted an immunohistochemical analysis of ATRX expression in adult diffuse gliomas and found ATRX immunoreactivity of tumor cells was either almost totally absent or completely retained in all cases. There was perfect concordance between the IHC results and ATRX mutation status. ATRX loss was observed in 54.5, 30.8 and 0.0% of grades II\/III astrocytomas, oligoastrocytomas and oligodendrogliomas, respectively, and 12.7% of glioblastomas. Another recent study analyzed the use of ATRX, IDH and 1p\/19q codeletion in a series astrocytomas, oligodendrogliomas, oligoastrocytomas and glioblastomas and presented an algorithm based on stepwise analysis with initial immunohistochemistry for ATRX and IDH1-R132H followed by 1p\/19q analysis then by IDH sequencing, which reduces the number of molecular analyses and which has a far better association with patient outcome.\u003c\/p\u003e","brand":"biosb","offers":[{"title":"BSB 3293,3.0 mL,Predilute","offer_id":49735310508272,"sku":"BSB 3293","price":216.0,"currency_code":"USD","in_stock":true},{"title":"BSB 3294,7.0 mL,Predilute","offer_id":49735310541040,"sku":"BSB 3294","price":390.0,"currency_code":"USD","in_stock":true},{"title":"BSB 3295,15.0 mL,Predilute","offer_id":49735310573808,"sku":"BSB 3295","price":702.0,"currency_code":"USD","in_stock":true},{"title":"BSB 3296,0.1 mL,Concentrate","offer_id":49735310606576,"sku":"BSB 3296","price":237.0,"currency_code":"USD","in_stock":true},{"title":"BSB 3297,0.5 mL,Concentrate","offer_id":49735310639344,"sku":"BSB 3297","price":528.0,"currency_code":"USD","in_stock":true},{"title":"BSB 3298,1.0 mL,Concentrate","offer_id":49735310672112,"sku":"BSB 3298","price":802.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0686\/3660\/6704\/files\/PI3298.jpg?v=1778683899"},{"product_id":"pi3712","title":"Aurora B","description":"\u003cp\u003eAurora B kinase, a 39.3 kDa sized serine-threonine kinase, is a member of the Aurora family of mitotic kinases. The enzymatic activity of Aurora B kinase prevents stable kinetochore-microtubule attachments in early mitosis and promotes stabilization of the attachments in later mitosis due to low activity. The gene for Aurora B kinase (AURKB) is located on chromosome 17p13.1.\n\u003cbr\u003e \n\u003cbr\u003e Abnormal expression of Aurora B kinase has been found in many cancer types, such as Non-Small Cell Lung Carcinoma, Mesothelioma, Glioblastoma, Oral Cancer and Hepatocellular Carcinoma. In Prostate and Colorectal Cancer, Aurora B expression directly correlates with the progression of cancer. In a study investigating the expression of Aurora B kinase in Thyroid Carcinoma, abundant expression of Aurora B kinase was detected in Anaplastic Carcinomas via IHC. A higher expression of Aurora B kinase in Anaplastic Thyroid Cancer than in differentiated Thyroid Cancer therefore suggests its use as a prognostic marker. In another immunohistochemical analysis, Aurora B kinase showed nuclear overexpression in high Gleason-grade Prostate Cancer, compared to low and intermediate grade cases. Additionally, there are numerous studies that indicate the use of Aurora B kinase as a prognostic marker in Ovarian Cancer. A study found that Aurora-B expression was correlated with the proliferation index (P \u0026lt; 0.001) and p53 expression (P = 0.014) in Breast cancer tissues and its expression was associated with lymph node metastasis (P = 0.002) and histological grade (P = 0.001). In conclusion, elevated Aurora-B expression in Breast Cancer patients contributes to chemoresistance and predicts poor prognosis.\u003c\/p\u003e","brand":"biosb","offers":[{"title":"BSB-3712-3,3.0 mL,Predilute","offer_id":49735310835952,"sku":"BSB-3712-3","price":250.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3712-7,7.0 mL,Predilute","offer_id":49735310868720,"sku":"BSB-3712-7","price":445.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3712-15,15.0 mL,Predilute","offer_id":49735310901488,"sku":"BSB-3712-15","price":784.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3712-01,0.1 mL,Concentrate","offer_id":49735310934256,"sku":"BSB-3712-01","price":258.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3712-05,0.5 mL,Concentrate","offer_id":49735310967024,"sku":"BSB-3712-05","price":561.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3712-1,1.0 mL,Concentrate","offer_id":49735310999792,"sku":"BSB-3712-1","price":893.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0686\/3660\/6704\/files\/PI3712.jpg?v=1778683971"},{"product_id":"pi2815","title":"B7H3\/CD276","description":"\u003cp\u003eB7-H3, also known as CD276, is a human protein encoded by the CD276 gene. The protein encoded by this gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues, such as melanoma, prostate cancer, and pancreatic cancer. B7-H3 mRNA is not detectable in peripheral blood mononuclear cells, although it is found in various normal tissues and in several tumor cell lines. Expression of B7-H3 protein, however, can be induced on dendritic cells (DCs) and monocytes by inflammatory cytokines. Soluble B7-H3 protein binds a putative counter-receptor on activated T cells that is distinct from CD28, cytotoxic T lymphocyte antigen 4 (CTLA-4), inducible costimulator (ICOS) and PD-1. B7-H3 costimulates proliferation of both CD4+ and CD8+ T cells, enhances the induction of cytotoxic T cells and selectively stimulates interferon gamma (IFN-gamma) production in the presence of T cell receptor signaling. \n\u003cbr\u003e \n\u003cbr\u003e Recently, B7-H3 expression has been reported in several human cancers indicating an additional function of B7-H3 as a regulator of antitumor immunity. However, its precise physiologic role is still elusive, because both stimulatory and inhibitory capacities have been demonstrated. B7H3 has been shown in recent years to be of clinical significance in different types of cancer. In some tumor types high expression of B7-H3 has been linked to a poor prognosis, whereas in other cancers the opposite effect has been observed. Taken together, the precise role of B7-H3 in tumor immunity is unclear and further research is needed. Another aspect of B7-H3, that so far has received little interest, is its role in non-immunological systems. It has been demonstrated that knockdown of B7-H3 in melanoma and breast cancer cells results in both increased chemosensitivity and decreased metastatic potential, which has been observed in both in vitro and in vivo experiments.\u003c\/p\u003e","brand":"biosb","offers":[{"title":"BSB 2810 (ASR),3.0 mL,Predilute","offer_id":50321128685808,"sku":"BSB 2810 (ASR)","price":440.0,"currency_code":"USD","in_stock":true},{"title":"BSB 2811 (ASR),7.0 mL,Predilute","offer_id":50321128718576,"sku":"BSB 2811 (ASR)","price":809.0,"currency_code":"USD","in_stock":true},{"title":"BSB 2812 (ASR),15.0 mL,Predilute","offer_id":50321128751344,"sku":"BSB 2812 (ASR)","price":1474.0,"currency_code":"USD","in_stock":true},{"title":"BSB 2813 (ASR),0.1 mL,Concentrate","offer_id":50321128784112,"sku":"BSB 2813 (ASR)","price":440.0,"currency_code":"USD","in_stock":true},{"title":"BSB 2814 (ASR),0.5 mL,Concentrate","offer_id":50321128816880,"sku":"BSB 2814 (ASR)","price":2211.0,"currency_code":"USD","in_stock":true},{"title":"BSB 2815 (ASR),1.0 mL,Concentrate","offer_id":50321128849648,"sku":"BSB 2815 (ASR)","price":3244.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0686\/3660\/6704\/files\/PI2815.jpg?v=1778684032"},{"product_id":"pi3305","title":"BAP1","description":"\u003cp\u003eBAP1 or BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) is a deubiquitinating enzyme that in humans is encoded by the BAP1 gene. Recent studies have shown that BAP1 and its fruit fly homolog, Calypso, are members of the polycomb-group proteins (PcG) of highly conserved transcriptional repressors required for long-term silencing of genes that regulate cell fate determination, stem cell pluripotency, and other developmental processes.\n\u003cbr\u003e \n\u003cbr\u003e In cancer, BAP1 can function both as a Tumor suppressor and as a metastasis suppressor. Exome sequencing identified inactivating mutations in BAP1 in 47% of Uveal melanomas, and BAP1 mutation have been found to be strongly associated with metastasis. The atypical melanocytic lesions resemble Spitz nevi and have been characterized as “atypical Spitz tumors” (ASTs), although they have a unique histology and exhibit both BRAF and BAP1 mutations.\n\u003cbr\u003e \n\u003cbr\u003e BAP1 mutations have been identified in aggressive Mesotheliomas with similar mutations as seen in melanomas. Sequencing studies have been used to identify germline mutations in BAP1 in families with genetic predispositions to mesothelioma and melanocytic skin tumors. Mutations in the tumor suppressor gene BAP1 occur in approximately 15% of clear cell renal cell carcinoma cases. Sequencing efforts demonstrated worse outcomes in patients with BAP1 mutated clear cell renal cell carcinoma. Immunohistochemistry for BAP1 is a prognostic biomarker to predict poor oncologic outcomes and adverse clinicopathological features in patients with non-metastatic clear cell renal cell carcinoma. BAP1 assessment using immunohistochemistry on needle biopsy may benefit preoperative risk stratification and guide treatment planning.\u003c\/p\u003e","brand":"biosb","offers":[{"title":"BSB 3300,3.0 mL,Predilute","offer_id":49735311524080,"sku":"BSB 3300","price":216.0,"currency_code":"USD","in_stock":true},{"title":"BSB 3301,7.0 mL,Predilute","offer_id":49735311556848,"sku":"BSB 3301","price":390.0,"currency_code":"USD","in_stock":true},{"title":"BSB 3302,15.0 mL,Predilute","offer_id":49735311589616,"sku":"BSB 3302","price":702.0,"currency_code":"USD","in_stock":true},{"title":"BSB 3303,0.1 mL,Concentrate","offer_id":49735311622384,"sku":"BSB 3303","price":237.0,"currency_code":"USD","in_stock":true},{"title":"BSB 3304,0.5 mL,Concentrate","offer_id":49735311655152,"sku":"BSB 3304","price":528.0,"currency_code":"USD","in_stock":true},{"title":"BSB 3305,1.0 mL,Concentrate","offer_id":49735311687920,"sku":"BSB 3305","price":802.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0686\/3660\/6704\/files\/PI3305.jpg?v=1778684104"},{"product_id":"pi6083","title":"Bax","description":"\u003cp\u003eBax is a protein of the bcl-2 gene family. It promotes apoptosis by competing with bcl-2 proper. The Bax gene contains a small promoter element that complements a binding domain on the multi-faceted p53 tumor suppressor. Wild-type p53 has been demonstrated to upregulate the transcription of a chimeric reporter plasmid, utilizing the consensus promoter sequence of Bax approx. 50-fold over mutant p53. Mutations in this consensus sequence eliminate transcription of the reporter gene. Thus, it is likely that p53 promotes Bax’s apoptotic faculties in vivo as a primary transcription factor.\n\u003cbr\u003e \n\u003cbr\u003e Bax exerts a pro-apoptotic rather than an anti-apoptotic effect on cells. Bax targets mitochondrial membranes, inducing mitochondrial damage and cell death in a caspase-independent manner. Bax plays a critical role in the Bax-mediated apoptosis pathway by dimerizing with BclxL, causing the displacement of Bax. The displacement of Bax allows apoptosis to proceed.\u003c\/p\u003e","brand":"biosb","offers":[{"title":"BSB 6078,3.0 mL,Predilute","offer_id":49735312244976,"sku":"BSB 6078","price":224.0,"currency_code":"USD","in_stock":true},{"title":"BSB 6079,7.0 mL,Predilute","offer_id":49735312277744,"sku":"BSB 6079","price":405.0,"currency_code":"USD","in_stock":true},{"title":"BSB 6080,15.0 mL,Predilute","offer_id":49735312310512,"sku":"BSB 6080","price":731.0,"currency_code":"USD","in_stock":true},{"title":"BSB 6081,0.1 mL,Concentrate","offer_id":49735312343280,"sku":"BSB 6081","price":249.0,"currency_code":"USD","in_stock":true},{"title":"BSB 6082,0.5 mL,Concentrate","offer_id":49735312376048,"sku":"BSB 6082","price":548.0,"currency_code":"USD","in_stock":true},{"title":"BSB 6083,1.0 mL,Concentrate","offer_id":49735312408816,"sku":"BSB 6083","price":836.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0686\/3660\/6704\/files\/PI6083.jpg?v=1778684157"},{"product_id":"pi5069","title":"BCA-225","description":"\u003cp\u003eThis antibody recognizes a human Breast Carcinoma-associated glycoprotein, BCA-225 (220-225 kDa). This protein differs in size and distribution from other Breast Carcinoma antigens. Unlike other carcinoma antibodies against Breast Carcinoma antigens, this antibody does not react with benign or malignant colonic tissues. Since this antigen is localized in malignancies of Breast Carcinomas and Carcinoma of the Uterine Cervix, it can be effectively used to identify metastatic Breast Carcinoma lesions.\n\u003cbr\u003e \n\u003cbr\u003e Strong intracytoplasmic staining is seen in primary and metastatic Breast Carcinoma tissue, as well as in Cervical Carcinomas. Apical staining is seen in normal kidney, lung, Fallopian tube, liver, skin (eccrine sweat glands) and uterus. Similar staining patterns are observed in lung, ovarian, and endometrial cancers. Carcinomas of the colon, stomach, prostate, urinary bladder, liver, pancreas, thyroid, and parotid are negative, as are Sarcomas and Lymphoid Cancers.\u003c\/p\u003e","brand":"biosb","offers":[{"title":"BSB 5064,3.0 mL,Predilute","offer_id":49735312933104,"sku":"BSB 5064","price":286.0,"currency_code":"USD","in_stock":true},{"title":"BSB 5065,7.0 mL,Predilute","offer_id":49735312965872,"sku":"BSB 5065","price":457.0,"currency_code":"USD","in_stock":true},{"title":"BSB 5066,15.0 mL,Predilute","offer_id":49735312998640,"sku":"BSB 5066","price":819.0,"currency_code":"USD","in_stock":true},{"title":"BSB 5067,0.1 mL,Concentrate","offer_id":49735313031408,"sku":"BSB 5067","price":162.0,"currency_code":"USD","in_stock":true},{"title":"BSB 5068,0.5 mL,Concentrate","offer_id":49735313064176,"sku":"BSB 5068","price":433.0,"currency_code":"USD","in_stock":true},{"title":"BSB 5069,1.0 mL,Concentrate","offer_id":49735313096944,"sku":"BSB 5069","price":608.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0686\/3660\/6704\/files\/PI5069.jpg?v=1778684244"},{"product_id":"pi2703","title":"bcl-10","description":"\u003cp\u003ebcl-10 (also known as B-cell lymphoma\/leukemia 10) is a 233 amino acid protein encoded by the BCL10 gene on Chromosome 1. The protein encoded by this gene contains a caspase recruitment domain , and has been shown to induce apoptosis and activate NF-kappaB. This protein is reported to interact with caspase recruitment domains (CARD) containing proteins including CARD9, 10, 11 and 14. These proteins function as upstream regulators in NF-kappaB signaling.\n\u003cbr\u003e \n\u003cbr\u003e Studies have shown that bcl-10 plays a critical role in the development of mucosa associated lymphoma tissue (MALT) lymphoma, and can be utilized in the classification of lymphomas. The antibody labels subpopulations of normal B and T cells. In MALT lymphomas with the t(1;14) translocation, the antibody strongly labeled the nuclei and cytoplasm, while 55% of MALT lymphomas lacking this translocation exhibited the same labeling pattern, although at a much lower level.\u003c\/p\u003e","brand":"biosb","offers":[{"title":"BSB 2698,3.0 mL,Predilute","offer_id":49735313522928,"sku":"BSB 2698","price":148.0,"currency_code":"USD","in_stock":true},{"title":"BSB 2699,7.0 mL,Predilute","offer_id":49735313555696,"sku":"BSB 2699","price":297.0,"currency_code":"USD","in_stock":true},{"title":"BSB 2700,15.0 mL,Predilute","offer_id":49735313588464,"sku":"BSB 2700","price":595.0,"currency_code":"USD","in_stock":true},{"title":"BSB 2701,0.1 mL,Concentrate","offer_id":49735313621232,"sku":"BSB 2701","price":129.0,"currency_code":"USD","in_stock":true},{"title":"BSB 2702,0.5 mL,Concentrate","offer_id":49735313654000,"sku":"BSB 2702","price":371.0,"currency_code":"USD","in_stock":true},{"title":"BSB 2703,1.0 mL,Concentrate","offer_id":49735313686768,"sku":"BSB 2703","price":743.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0686\/3660\/6704\/files\/PI2703.jpg?v=1778684301"},{"product_id":"pi6546","title":"bcl-2","description":"\u003cp\u003ebcl-2 is an integral outer mitochondrial membrane protein that regulates apoptosis of some cells such as lymphocytes. Constitutive expression of bcl-2, such as in the case of translocation of bcl-2 to Ig heavy-chain loci, is thought to be the cause of Follicular Lymphoma.\n\u003cbr\u003e \n\u003cbr\u003e Anti-bcl-2 has shown consistent negative reaction on reactive germinal centers and positive staining of neoplastic follicles in Follicular Lymphoma. Consequently, this antibody is valuable when distinguishing between reactive and neoplastic follicular proliferation in lymph node biopsies. This antibody may also be used in distinguishing between those Follicular Lymphomas that express bcl-2 protein and the small number in which the neoplastic cells are bcl-2-negative. Anti-bcl-2 has been used as a predictive biomarker for recurrence of Cancer of the Breast and Non-Small-Cell Carcinoma of the Lung.\u003c\/p\u003e","brand":"biosb","offers":[{"title":"BSB 6541,3.0 mL,Predilute","offer_id":49735314505968,"sku":"BSB 6541","price":291.0,"currency_code":"USD","in_stock":true},{"title":"BSB 6542,7.0 mL,Predilute","offer_id":49735314538736,"sku":"BSB 6542","price":526.0,"currency_code":"USD","in_stock":true},{"title":"BSB 6543,15.0 mL,Predilute","offer_id":49735314571504,"sku":"BSB 6543","price":945.0,"currency_code":"USD","in_stock":true},{"title":"BSB 6544,0.1 mL,Concentrate","offer_id":49735314604272,"sku":"BSB 6544","price":323.0,"currency_code":"USD","in_stock":true},{"title":"BSB 6545,0.5 mL,Concentrate","offer_id":49735314637040,"sku":"BSB 6545","price":711.0,"currency_code":"USD","in_stock":true},{"title":"BSB 6546,1.0 mL,Concentrate","offer_id":49735314669808,"sku":"BSB 6546","price":1085.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0686\/3660\/6704\/files\/PI6546.jpg?v=1778684371"},{"product_id":"pi5076","title":"bcl-2","description":"\u003cp\u003ebcl-2 is an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of bcl-2, such as in the case of translocation of bcl-2 to Ig heavy chain loci, is thought to be the cause of Follicular Lymphoma.\n\u003cbr\u003e \n\u003cbr\u003e Anti-bcl-2 has shown consistent negative reaction on reactive germinal centers and positive staining of neoplastic follicles in Follicular Lymphoma. Consequently, this antibody is valuable when distinguishing between reactive and neoplastic follicular proliferation in lymph node biopsies. This antibody may also be used in distinguishing between those Follicular Lymphomas that express bcl-2 protein and the small number in which the neoplastic cells are bcl-2-negative. Anti-bcl-2 has been used as a predictive biomarker for recurrence of Cancer of the Breast and Non-Small-Cell Carcinoma of the Lung.\u003c\/p\u003e","brand":"biosb","offers":[{"title":"BSB 5071,3.0 mL,Predilute","offer_id":49735315063024,"sku":"BSB 5071","price":144.0,"currency_code":"USD","in_stock":true},{"title":"BSB 5072,7.0 mL,Predilute","offer_id":49735315095792,"sku":"BSB 5072","price":180.0,"currency_code":"USD","in_stock":true},{"title":"BSB 5073,15.0 mL,Predilute","offer_id":49735315128560,"sku":"BSB 5073","price":349.0,"currency_code":"USD","in_stock":true},{"title":"BSB 5074,0.1 mL,Concentrate","offer_id":49735315161328,"sku":"BSB 5074","price":136.0,"currency_code":"USD","in_stock":true},{"title":"BSB 5075,0.5 mL,Concentrate","offer_id":49735315194096,"sku":"BSB 5075","price":262.0,"currency_code":"USD","in_stock":true},{"title":"BSB 5076,1.0 mL,Concentrate","offer_id":49735315226864,"sku":"BSB 5076","price":354.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0686\/3660\/6704\/files\/PI5076.jpg?v=1778684456"},{"product_id":"pi2822","title":"bcl-6","description":"\u003cp\u003ebcl-6 is a transcriptional regulator gene which codes for a 706-amino-acid nuclear zinc finger protein. Antibodies to this protein stain the germinal center cells in lymphoid follicles, follicular cells and interfollicular cells in Follicular Lymphoma, Diffuse Large B-Cell Lymphomas, Burkitt’s Lymphoma, and the majority of the Reed-Sternberg cells in Nodular Lymphocyte-Predominant Hodgkin’s Disease. bcl-6 is also useful in identifying neoplastic cells in cases of nodular Lymphocyte-Predominant Hodgkin’s Disease. In contrast, anti-bcl-6 rarely stains Mantle-Cell Lymphoma and MALT Lymphoma. bcl-6 expression is seen in approximately 45% of CD30+ Anaplastic Large-Cell Lymphomas but is consistently absent in other peripheral T-cell Lymphomas.\u003c\/p\u003e","brand":"biosb","offers":[{"title":"BSB 2817,3.0 mL,Predilute","offer_id":49735315718384,"sku":"BSB 2817","price":304.0,"currency_code":"USD","in_stock":true},{"title":"BSB 2818,7.0 mL,Predilute","offer_id":49735315751152,"sku":"BSB 2818","price":548.0,"currency_code":"USD","in_stock":true},{"title":"BSB 2819,15.0 mL,Predilute","offer_id":49735315783920,"sku":"BSB 2819","price":996.0,"currency_code":"USD","in_stock":true},{"title":"BSB 2820,0.1 mL,Concentrate","offer_id":49735315816688,"sku":"BSB 2820","price":306.0,"currency_code":"USD","in_stock":true},{"title":"BSB 2821,0.5 mL,Concentrate","offer_id":49735315849456,"sku":"BSB 2821","price":744.0,"currency_code":"USD","in_stock":true},{"title":"BSB 2822,1.0 mL,Concentrate","offer_id":49735315882224,"sku":"BSB 2822","price":1184.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0686\/3660\/6704\/files\/PI2822.jpg?v=1778684517"},{"product_id":"pi5083","title":"bcl-6","description":"\u003cp\u003ebcl-6 is a transcriptional regulator gene which codes for a 706-amino-acid nuclear zinc finger protein. Antibodies to this protein stain the germinal center cells in lymphoid follicles, follicular cells and interfollicular cells in Follicular Lymphoma, Diffuse Large B-Cell Lymphomas, Burkitt’s Lymphoma, and the majority of the\n\u003cbr\u003e Reed-Sternberg cells in Nodular Lymphocyte-Predominant Hodgkin’s Disease.\n\u003cbr\u003e \n\u003cbr\u003e bcl-6 is also useful in identifying neoplastic cells in cases of nodular Lymphocyte-Predominant Hodgkin’s Disease. In contrast, anti-bcl-6 rarely stains Mantle-Cell Lymphoma and MALT Lymphoma. bcl-6 expression is seen in approximately 45% of CD30+ Anaplastic Large-Cell Lymphomas but is consistently absent in other\n\u003cbr\u003e peripheral T-cell Lymphomas.\u003c\/p\u003e","brand":"biosb","offers":[{"title":"BSB 5078,3.0 mL,Predilute","offer_id":49735316570352,"sku":"BSB 5078","price":327.0,"currency_code":"USD","in_stock":true},{"title":"BSB 5079,7.0 mL,Predilute","offer_id":49735316603120,"sku":"BSB 5079","price":540.0,"currency_code":"USD","in_stock":true},{"title":"BSB 5080,15.0 mL,Predilute","offer_id":49735316635888,"sku":"BSB 5080","price":984.0,"currency_code":"USD","in_stock":true},{"title":"BSB 5081,0.1 mL,Concentrate","offer_id":49735316668656,"sku":"BSB 5081","price":315.0,"currency_code":"USD","in_stock":true},{"title":"BSB 5082,0.5 mL,Concentrate","offer_id":49735316701424,"sku":"BSB 5082","price":708.0,"currency_code":"USD","in_stock":true},{"title":"BSB 5083,1.0 mL,Concentrate","offer_id":49735316734192,"sku":"BSB 5083","price":1081.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0686\/3660\/6704\/files\/PI5083.jpg?v=1778684564"},{"product_id":"pi3439","title":"bcl-6","description":"\u003cp\u003ebcl-6 is a transcriptional regulator gene which codes for a 706-amino-acid nuclear zinc finger protein. Antibodies to this protein stain the germinal center cells in lymphoid follicles, follicular cells and interfollicular cells in Follicular Lymphoma, Diffuse Large B-Cell Lymphomas, Burkitt’s Lymphoma, and the majority of the\n\u003cbr\u003e Reed-Sternberg cells in Nodular Lymphocyte-Predominant Hodgkin’s Disease.\n\u003cbr\u003e \n\u003cbr\u003e bcl-6 is also useful in identifying neoplastic cells in cases of nodular Lymphocyte-Predominant Hodgkin’s Disease. In contrast, anti-bcl-6 rarely stains Mantle-Cell Lymphoma and MALT Lymphoma. bcl-6 expression is seen in approximately 45% of CD30+ Anaplastic Large-Cell Lymphomas but is consistently absent in other\n\u003cbr\u003e peripheral T-cell Lymphomas.\u003c\/p\u003e","brand":"biosb","offers":[{"title":"BSB 3434,3.0 mL,Predilute","offer_id":49735317225712,"sku":"BSB 3434","price":172.0,"currency_code":"USD","in_stock":true},{"title":"BSB 3435,7.0 mL,Predilute","offer_id":49735317258480,"sku":"BSB 3435","price":313.0,"currency_code":"USD","in_stock":true},{"title":"BSB 3436,15.0 mL,Predilute","offer_id":49735317291248,"sku":"BSB 3436","price":564.0,"currency_code":"USD","in_stock":true},{"title":"BSB 3437,0.1 mL,Concentrate","offer_id":49735317324016,"sku":"BSB 3437","price":153.0,"currency_code":"USD","in_stock":true},{"title":"BSB 3438,0.5 mL,Concentrate","offer_id":49735317356784,"sku":"BSB 3438","price":390.0,"currency_code":"USD","in_stock":true},{"title":"BSB 3439,1.0 mL,Concentrate","offer_id":49735317389552,"sku":"BSB 3439","price":663.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0686\/3660\/6704\/files\/PI3439.jpg?v=1778684628"},{"product_id":"pi2370","title":"BCOR","description":"\u003cp\u003eBCOR is located on chromosome X, in the Xp11.4 locus, and derives its name from its function as an interacting corepressor of BCL-6 that enhances BCL-6-mediated transcriptional repression. BCOR is a gene that encodes for an epigenetic regulator involved in the specification of cell differentiation and body structure development. Various BCOR aberrations, represent driver elements of various sarcomas such as Clear Cell Sarcoma of the Kidney, Primitive Mesenchymal Myxoid Tumor of infancy, small round blue cell sarcoma, endometrial stromal sarcoma and histologically heterogeneous CNS neoplasms group with similar genomic methylation patterns known as CNS-HGNET-BCOR. Furthermore, other BCOR alterations (often loss of function mutations) recur in a large variety of Mesenchymal, Epithelial, Neural and Hematological Tumors, suggesting a central role in cancer evolution.\n\u003cbr\u003e \n\u003cbr\u003e Using next-generation sequencing, an increasing number of novel gene fusions and other abnormalities have emerged recently in the spectrum of EWSR1-negative Small Blue Round Cell Tumors (SBRCTs). A subset of SBRCTs harboring either BCOR gene fusions (BCOR-CCNB3, BCOR-MAML3), BCOR internal tandem duplications (ITD), or YWHAENUTM2B share a transcriptional signature including high BCOR mRNA expression, as well as similar histologic features. Furthermore, other tumors such as Clear Cell Sarcoma of Kidney (CCSK) and Primitive Myxoid Mesenchymal Tumor of Infancy (PMMTI) also demonstrate BCOR ITDs and high BCOR gene expression. Recent studies have found the IHC of BCOR to be a highly sensitive marker for SBRCTs and CCSKs with BCOR abnormalities and YWHAE rearrangements and can be used as a useful diagnostic marker in these various molecular subsets.\n\u003cbr\u003e \n\u003cbr\u003e In another study, Strong diffuse nuclear BCOR staining (defined as \u0026gt;95% of tumor cells) was seen in the round cell component of 20 (100%) classic YWHAE-NUTM2 high-grade Endometrial Stromal Sarcomas and the 3 unusual high-grade Endometrial Stromal Sarcomas. It was concluded that BCOR immunohistochemical staining is a highly sensitive marker for YWHAE-NUTM2 high-grade Endometrial Stromal Sarcomas with both classic and unusual morphology and identifies a subset of high-grade Endometrial Stromal Sarcomas with BCOR alterations, including BCOR rearrangement and internal tandem duplication.\u003c\/p\u003e","brand":"biosb","offers":[{"title":"BSB-2370-3,3.0 mL,Tinto Predilute","offer_id":49735317782768,"sku":"BSB-2370-3","price":166.0,"currency_code":"USD","in_stock":true},{"title":"BSB-2370-7,7.0 mL,Tinto Predilute","offer_id":49735317815536,"sku":"BSB-2370-7","price":505.0,"currency_code":"USD","in_stock":true},{"title":"BSB-2370-15,15.0 mL,Tinto Predilute","offer_id":49735317848304,"sku":"BSB-2370-15","price":1010.0,"currency_code":"USD","in_stock":true},{"title":"BSB-2370-01,0.1 mL,Concentrate","offer_id":49735317881072,"sku":"BSB-2370-01","price":208.0,"currency_code":"USD","in_stock":true},{"title":"BSB-2370-05,0.5 mL,Concentrate","offer_id":49735317913840,"sku":"BSB-2370-05","price":542.0,"currency_code":"USD","in_stock":true},{"title":"BSB-2370-1,1.0 mL,Concentrate","offer_id":49735317946608,"sku":"BSB-2370-1","price":951.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0686\/3660\/6704\/files\/PI2370.jpg?v=1778684685"},{"product_id":"pi3756","title":"Beta-Catenin","description":"\u003cp\u003eBeta-Catenin is a subunit of the Cadherin protein complex. Cadherins are a type of protein normally expressed on the surface of certain cells. Specifically, Beta Catenin is a 92 kDa protein normally found in the cytoplasm of the cell in the sub-membranous location. This protein is associated with E-Cadherin and may be essential for the function of E-Cadherin.\n\u003cbr\u003e \n\u003cbr\u003e Mutations in the Beta-Catenin gene result in the nuclear accumulation of this protein. Nuclear accumulation of this protein has been demonstrated in Fibromatosis lesions of the breast and abdomen, and therefore is useful in differentiating this lesion from other spindle-cell lesions that may occur in these locations\u003c\/p\u003e","brand":"biosb","offers":[{"title":"BSB-3756-3,3.0 mL,Predilute","offer_id":49735318307056,"sku":"BSB-3756-3","price":216.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3756-7,7.0 mL,Predilute","offer_id":49735318339824,"sku":"BSB-3756-7","price":391.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3756-15,15.0 mL,Predilute","offer_id":49735318372592,"sku":"BSB-3756-15","price":703.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3756-01,0.1 mL,Concentrate","offer_id":49735318405360,"sku":"BSB-3756-01","price":283.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3756-05,0.5 mL,Concentrate","offer_id":49735318438128,"sku":"BSB-3756-05","price":564.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3756-1,1.0 mL,Concentrate","offer_id":49735318470896,"sku":"BSB-3756-1","price":956.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0686\/3660\/6704\/files\/PI3756.jpg?v=1778684750"},{"product_id":"pi5090","title":"Beta-Catenin","description":"\u003cp\u003eBeta-Catenin is a subunit of the Cadherin protein complex. Cadherins are a type of protein normally expressed on the surface of certain cells. Specifically, Beta Catenin is a 92 kDa protein normally found in the cytoplasm of the cell in the sub-membranous location. This protein is associated with E-Cadherin and may be essential for the function of E-Cadherin.\n\u003cbr\u003e \n\u003cbr\u003e Mutations in the Beta-Catenin gene result in the nuclear accumulation of this protein. Nuclear accumulation of this protein has been demonstrated in Fibromatosis lesions of the breast and abdomen, and therefore is useful in differentiating this lesion from other spindle-cell lesions that may occur in these locations.\u003c\/p\u003e","brand":"biosb","offers":[{"title":"BSB 5085,3.0 mL,Predilute","offer_id":49735318962416,"sku":"BSB 5085","price":146.0,"currency_code":"USD","in_stock":true},{"title":"BSB 5086,7.0 mL,Predilute","offer_id":49735318995184,"sku":"BSB 5086","price":368.0,"currency_code":"USD","in_stock":true},{"title":"BSB 5087,15.0 mL,Predilute","offer_id":49735319027952,"sku":"BSB 5087","price":665.0,"currency_code":"USD","in_stock":true},{"title":"BSB 5088,0.1 mL,Concentrate","offer_id":49735319060720,"sku":"BSB 5088","price":169.0,"currency_code":"USD","in_stock":true},{"title":"BSB 5089,0.5 mL,Concentrate","offer_id":49735319093488,"sku":"BSB 5089","price":339.0,"currency_code":"USD","in_stock":true},{"title":"BSB 5090,1.0 mL,Concentrate","offer_id":49735319126256,"sku":"BSB 5090","price":597.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0686\/3660\/6704\/files\/PI5090.jpg?v=1778684822"},{"product_id":"pi6378","title":"BG8 LewisY","description":"\u003cp\u003eBlood group antigens have been examined as potential discriminators between pulmonary adenocarcinoma (PACA) and epithelioid mesothelioma (EM). LewisY is the only one of these that appears to have some merit. BG8 is raised from the SK-LU-3 lung cancer line and is able to distinguish between PACA and EM. Studies of\n\u003cbr\u003e \n\u003cbr\u003e 231 cases of PACA and 197 cases of EM have shown that sensitivity and specificity for PACA were both 93%. It has been reported that sensitivity of nonmesothelial antigens for adenocarcinoma is organ dependent, with BG8 Lewis performing at 98% in the breast cancer group, and 100% in the lung cancer group. The specificity of the nonmesothelial (non-EM) antigens for adenocarcinoma was 98% for BG8.\n\u003cbr\u003e \n\u003cbr\u003e It has been concluded using logical regression analysis that a three-antibody immunohistochemical panel including Calretinin, BG8, and MOC-31 would provide 96% sensitivity and specificity for distinguishing EM from Adenocarcinoma in a variety of sources (lung, ovary, breast, stomach).\u003c\/p\u003e","brand":"biosb","offers":[{"title":"BSB 6373,3.0 mL,Predilute","offer_id":49735319486704,"sku":"BSB 6373","price":157.0,"currency_code":"USD","in_stock":true},{"title":"BSB 6374,7.0 mL,Predilute","offer_id":49735319519472,"sku":"BSB 6374","price":290.0,"currency_code":"USD","in_stock":true},{"title":"BSB 6375,15.0 mL,Predilute","offer_id":49735319552240,"sku":"BSB 6375","price":518.0,"currency_code":"USD","in_stock":true},{"title":"BSB 6376,0.1 mL,Concentrate","offer_id":49735319585008,"sku":"BSB 6376","price":123.0,"currency_code":"USD","in_stock":true},{"title":"BSB 6377,0.5 mL,Concentrate","offer_id":49735319617776,"sku":"BSB 6377","price":341.0,"currency_code":"USD","in_stock":true},{"title":"BSB 6378,1.0 mL,Concentrate","offer_id":49735319650544,"sku":"BSB 6378","price":656.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0686\/3660\/6704\/files\/PI6378.jpg?v=1778684874"},{"product_id":"pi3700","title":"BOB.1","description":"\u003cp\u003eThe BOB-1 protein is a co-activator that interacts with Oct1 and\/or Oct2 transcription factors, and is critical in germinal center formation and immunoglobulin production. The strongest expression of BOB-1 is found in the germinal center, mantle-zone B cells, and plasma cells. Because BOB-1\/OBF.1 are germinal center derived, L\u0026amp;H cells in Nodular Lymphocyte Predominant Hodgkin Lymphoma are consistently immunoreactive for BOB-1. Conversely, the Hodgkin\/Reed-Sternberg cells in classical Hodgkin Lymphoma either do not express both or express only one of the two proteins.\n\u003cbr\u003e \n\u003cbr\u003e In Diffuse Large B-cell Lymphomas, the highest expression levels for BOB-1\/OBF.1 are reported in Follicular Center Lymphomas, Diffuse Large B-cell Lymphomas, and Burkitt Lymphomas. B-CLL, MALT-type, and Mantle Cell Lymphomas score negative or display a heterogenous\/weaker activity. The strong nuclear expression of BOB-1 and Oct-2 by Germinal Center Derived Lymphomas makes these antibodies a novel class of broad spectrum B-lineage immunohistochemical markers in the differential diagnosis of Lymphomas, specifically between Primary Mediastinal B-cell Lymphoma from classical Hodgkin Disease.\u003c\/p\u003e","brand":"biosb","offers":[{"title":"BSB-3700-3,3.0 mL,Predilute","offer_id":49735320043760,"sku":"BSB-3700-3","price":286.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3700-7,7.0 mL,Predilute","offer_id":49735320076528,"sku":"BSB-3700-7","price":513.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3700-15,15.0 mL,Predilute","offer_id":49735320109296,"sku":"BSB-3700-15","price":924.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3700-01,0.1 mL,Concentrate","offer_id":49735320142064,"sku":"BSB-3700-01","price":315.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3700-05,0.5 mL,Concentrate","offer_id":49735320174832,"sku":"BSB-3700-05","price":695.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3700-1,1.0 mL,Concentrate","offer_id":49735320207600,"sku":"BSB-3700-1","price":1062.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0686\/3660\/6704\/files\/PI3700.jpg?v=1778684934"},{"product_id":"pi3495","title":"Brachyury","description":"\u003cp\u003eBrachyury is a protein that in humans is encoded by the T gene. Brachyury is a transcription factor within the T-box complex of genes which appears to have a conserved role in defining the midline of a bilaterian organism and thus the establishment of the anterior-posterior axis; this function is apparent in chordates and molluscs. The number of cervical vertebrae is highly conserved among all mammals; however a spontaneous vertebral and spinal dysplasia (VSD) mutation in this gene has been associated with the development of six or fewer cervical vertebrae instead of the usual seven. \n\u003cbr\u003e \n\u003cbr\u003e Expression of the brachyury gene has been identified as a definitive diagnostic marker of chordoma, a malignant tumor that arises from remnant notochordal cells lodged in the vertebrae. Furthermore, germ line duplication of brachyury confers major susceptibility to chordoma. The chromosomal region on 6q27 containing the brachyury gene was gained in 6 of 21 chordomas (29%), and none of the 21 chordomas analyzed showed deletions that could have affected this gene. \n\u003cbr\u003e \n\u003cbr\u003e Brachyury is an important factor in promoting the epithelial-mesenchymal transition (EMT). Cells that over-express brachyury have down-regulated expression of the adhesion molecule E-cadherin, which allows them to undergo EMT. Overexpression of brachyury has been linked to Hepatocellular carcinoma. While brachyury is promoting EMT, it can also induce metastasis of HCC cells. Brachyury expression is a prognostic biomarker for HCC, and the gene may be a target for cancer treatments in the future. Additionally, overexpression of brachyury may play a part in EMT associated with benign disease such as renal fibrosis.\u003c\/p\u003e","brand":"biosb","offers":[{"title":"BSB 3490,3.0 mL,Predilute","offer_id":49735320699120,"sku":"BSB 3490","price":257.0,"currency_code":"USD","in_stock":true},{"title":"BSB 3491,7.0 mL,Predilute","offer_id":49735320731888,"sku":"BSB 3491","price":464.0,"currency_code":"USD","in_stock":true},{"title":"BSB 3492,15.0 mL,Predilute","offer_id":49735320764656,"sku":"BSB 3492","price":836.0,"currency_code":"USD","in_stock":true},{"title":"BSB 3493,0.1 mL,Concentrate","offer_id":49735320797424,"sku":"BSB 3493","price":284.0,"currency_code":"USD","in_stock":true},{"title":"BSB 3494,0.5 mL,Concentrate","offer_id":49735320830192,"sku":"BSB 3494","price":629.0,"currency_code":"USD","in_stock":true},{"title":"BSB 3495,1.0 mL,Concentrate","offer_id":49735320862960,"sku":"BSB 3495","price":956.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0686\/3660\/6704\/files\/PI3495.jpg?v=1778684982"},{"product_id":"pi2829","title":"BRAF V600E","description":"\u003cp\u003eBRAF is a human gene that makes a protein called B-Raf, which is more formally known as serine\/threonine-protein kinase B-Raf. The B-Raf protein is involved in sending signals inside cells, which are involved in directing cell growth. In 2002, it was shown to be mutated in some human cancers. Mutations in the BRAF gene can cause disease in two ways. First, mutations can be inherited and cause birth defects. Second, mutations can appear later in life and cause cancer, as an oncogene.\n\u003cbr\u003e \n\u003cbr\u003e Mutations in this gene have been found in cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, papillary thyroid carcinoma, non-small-cell lung carcinoma, and adenocarcinoma of the lung. The frequency of BRAF mutations varies widely in human cancers, from more than 80% in melanomas and nevi, to as little as 0–18% in other tumors, such as 1–3% in lung cancers and 5% in colorectal cancer. In 90% of the cases, thymine is substituted with adenine at nucleotide 1799. This leads to valine (V) being substituted for by glutamate (E) at codon 600 (referred to as V600E) in the activation segment that has been found in human cancers. This mutation has been widely observed in papillary thyroid carcinoma, colorectal cancer, melanoma and non-small-cell lung cancer. BRAF-V600E mutation are present in 57% of Langerhans cell histiocytosis patients. The V600E mutation is a likely driver mutation in 100% of cases of hairy cell leukemia. High frequency of BRAF V600E mutations have been detected in ameloblastoma, a benign but locally infiltrative odontogenic neoplasm.\u003c\/p\u003e","brand":"biosb","offers":[{"title":"BSB 2824 (ASR),3.0 mL,Predilute","offer_id":50321131634928,"sku":"BSB 2824 (ASR)","price":378.0,"currency_code":"USD","in_stock":true},{"title":"BSB 2825 (ASR),7.0 mL,Predilute","offer_id":50321131667696,"sku":"BSB 2825 (ASR)","price":760.0,"currency_code":"USD","in_stock":true},{"title":"BSB 2826 (ASR),15.0 mL,Predilute","offer_id":50321131700464,"sku":"BSB 2826 (ASR)","price":1223.0,"currency_code":"USD","in_stock":true},{"title":"BSB 2827 (ASR),0.1 mL,Concentrate","offer_id":50321131733232,"sku":"BSB 2827 (ASR)","price":591.0,"currency_code":"USD","in_stock":true},{"title":"BSB 2828 (ASR),0.5 mL,Concentrate","offer_id":50321131766000,"sku":"BSB 2828 (ASR)","price":1223.0,"currency_code":"USD","in_stock":true},{"title":"BSB 2829 (ASR),1.0 mL,Concentrate","offer_id":50321131798768,"sku":"BSB 2829 (ASR)","price":2065.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0686\/3660\/6704\/files\/PI2829.jpg?v=1778685028"},{"product_id":"pi3714","title":"BRG-1\/SMARCA4","description":"\u003cp\u003eBrahma-related gene-1 (BRG-1) protein is encoded by the gene SMARCA-4, which is localized on chromosome 19. BRG-1 is the core catalytic ATPase subunit of the SWItch\/sucrose non-fermentable (SWI\/SNF) complex. SWI\/SNFs are a member of the family of ATP-dependent chromatin-remodeling complexes and the function of SWI\/SNFs is to facilitate the transcriptional activation or repression of target genes. BRG-1 is essential for DNA repair, differentiation, and organ development. \n\u003cbr\u003e There are several studies that suggest the involvement of BRG-1 in different cancer types. It was found that the loss of BRG-1 expression occurs in a portion of tested cancers types, including Breast, Colon, Head\/Neck, Ovarian, Liver and Renal Cell Cancer. On the contrary, overexpression of BRG-1 was found in Breast, Colorectal, and Prostate Cancer, as well as Melanoma and Neuroblastoma. There is no established cutoff for determining high versus low expression; staining of the surrounding normal tissue has been used as a median value relative to which BRG-1\/SMARCA4 expression may be considered increased or decreased. An IHC analysis of BRG-1 in Non-Small Cell Lung Cancer (NSCLC) patients revealed that the survival rate of BRG-1 negative patients was 0%, when compared to BRG-1 positive patients, indicating the prognostic value of BRG-1 as a biomarker. Other IHC studies found that the loss of BRG-1 protein expression highly correlates with Small Cell Carcinoma of the Ovary, Hypercalcemic type (SCCOHT), suggesting BRG-1 as a diagnostic marker for SCCOHT.\u003c\/p\u003e","brand":"biosb","offers":[{"title":"BSB-3714-3,3.0 mL,Predilute","offer_id":49735321813232,"sku":"BSB-3714-3","price":233.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3714-7,7.0 mL,Predilute","offer_id":49735321846000,"sku":"BSB-3714-7","price":420.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3714-15,15.0 mL,Predilute","offer_id":49735321878768,"sku":"BSB-3714-15","price":738.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3714-01,0.1 mL,Concentrate","offer_id":49735321911536,"sku":"BSB-3714-01","price":243.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3714-05,0.5 mL,Concentrate","offer_id":49735321944304,"sku":"BSB-3714-05","price":530.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3714-1,1.0 mL,Concentrate","offer_id":49735321977072,"sku":"BSB-3714-1","price":873.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0686\/3660\/6704\/files\/PI3714.jpg?v=1778685072"},{"product_id":"pi6588","title":"c-Met\/HGFR","description":"\u003cp\u003ec-Met is a proto-oncogene that encodes hepatocyte growth factor receptor (HGFR). The HGFR protein possesses tyrosinase-kinase activity. MET is a membrane receptor that is essential for embryonic development and wound healing, with its only known ligand being hepatocyte growth factor (HGF). Met is normally expressed by cells of epithelial origin, while expression of HGF is restricted to cells of mesenchymal origin. Upon HGF stimulation, MET induces several biological responses that collectively give rise to a program known as invasive growth.\n\u003cbr\u003e \n\u003cbr\u003e MET is deregulated in many types of human malignancies, including cancers of kidney, liver, stomach, breast, and brain. Normally, only stem cells and progenitor cells express MET, which allows these cells to grow invasively in order to generate new tissues in an embryo or regenerate damaged tissues in an adult. However, cancer stem cells are thought to hijack the ability to express MET, and thus become the cause of cancer persistence and spread to other sites in the body (metastasis).\u003c\/p\u003e","brand":"biosb","offers":[{"title":"BSB 6583,3.0 mL,Predilute","offer_id":49735322468592,"sku":"BSB 6583","price":365.0,"currency_code":"USD","in_stock":true},{"title":"BSB 6584,7.0 mL,Predilute","offer_id":49735322501360,"sku":"BSB 6584","price":665.0,"currency_code":"USD","in_stock":true},{"title":"BSB 6585,15.0 mL,Predilute","offer_id":49735322534128,"sku":"BSB 6585","price":1192.0,"currency_code":"USD","in_stock":true},{"title":"BSB 6586,0.1 mL,Concentrate","offer_id":49735322566896,"sku":"BSB 6586","price":400.0,"currency_code":"USD","in_stock":true},{"title":"BSB 6587,0.5 mL,Concentrate","offer_id":49735322599664,"sku":"BSB 6587","price":1080.0,"currency_code":"USD","in_stock":true},{"title":"BSB 6588,1.0 mL,Concentrate","offer_id":49735322632432,"sku":"BSB 6588","price":1630.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0686\/3660\/6704\/files\/PI6588.jpg?v=1778685137"},{"product_id":"pi3812","title":"c-Met\/HGFR","description":"\u003cp\u003eMET is a proto-oncogene that encodes hepatocyte growth factor receptor (HGFR). The c-Met\/HGFR protein possesses tyrosinase-kinase activity and is a membrane receptor essential for embryonic development and wound healing, with its only known ligand being hepatocyte growth factor (HGF). Upon HGF stimulation, MET induces several biological responses that collectively give rise to a program known as invasive growth.\n\u003cbr\u003e \n\u003cbr\u003e The c-Met protein is deregulated in many types of human malignancies, including cancers of kidney, liver, stomach, breast, and brain. Normally, only stem cells and progenitor cells express the MET gene, which allows these cells to grow invasively in order to generate new tissues in an embryo or regenerate damaged tissues in an adult. However, cancer stem cells are thought to hijack the ability to express the MET gene, and thus become the cause of cancer persistence and spread to other sites in the body (metastasis).\u003c\/p\u003e","brand":"biosb","offers":[{"title":"BSB-3812-3,3.0 mL,Predilute","offer_id":49735323058416,"sku":"BSB-3812-3","price":305.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3812-7,7.0 mL,Predilute","offer_id":49735323091184,"sku":"BSB-3812-7","price":509.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3812-15,15.0 mL,Predilute","offer_id":49735323123952,"sku":"BSB-3812-15","price":916.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3812-01,0.1 mL,Concentrate","offer_id":49735323156720,"sku":"BSB-3812-01","price":325.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3812-05,0.5 mL,Concentrate","offer_id":49735323189488,"sku":"BSB-3812-05","price":693.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3812-1,1.0 mL,Concentrate","offer_id":49735323222256,"sku":"BSB-3812-1","price":1018.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0686\/3660\/6704\/files\/PI3812.jpg?v=1778685188"},{"product_id":"pi3813","title":"c-Myc","description":"\u003cp\u003eOncogene-encoded proteins c-Myc, N-Myc, and L-Myc function in cell proliferation, differentiation and neoplastic disease. A mutated version of MYC is found in many cancers, which causes Myc to be constitutively expressed. This leads to the unregulated expression of many genes, some of which are involved in cell proliferation, and results in the formation of cancer. c-Myc is a transcription factor and is a proto-oncogene that is the focal point in cell cycle regulation, metabolism, apoptosis, differentiation, cell adhesion, and tumorigenesis.\n\u003cbr\u003e \n\u003cbr\u003e A common human translocation involving Myc is t(8; 14) which is critical to the development of most cases of Burkitt’s Lymphoma. Malfunctions in Myc have also been found in carcinoma of the cervix, colon, breast, lung, and stomach.\u003c\/p\u003e","brand":"biosb","offers":[{"title":"BSB-3813-3,3.0 mL,Predilute","offer_id":49735323877616,"sku":"BSB-3813-3","price":305.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3813-7,7.0 mL,Predilute","offer_id":49735323910384,"sku":"BSB-3813-7","price":509.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3813-15,15.0 mL,Predilute","offer_id":49735323943152,"sku":"BSB-3813-15","price":916.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3813-01,0.1 mL,Concentrate","offer_id":49735323975920,"sku":"BSB-3813-01","price":325.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3813-05,0.5 mL,Concentrate","offer_id":49735324008688,"sku":"BSB-3813-05","price":693.0,"currency_code":"USD","in_stock":true},{"title":"BSB-3813-1,1.0 mL,Concentrate","offer_id":49735324041456,"sku":"BSB-3813-1","price":1018.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0686\/3660\/6704\/files\/PI3813.jpg?v=1778685293"},{"product_id":"pi3024","title":"C1q","description":"\u003cp\u003eThe complement component 1q (C1q) is a protein complex involved in the complement system, which is part of the innate immune system. C1q together with C1r and C1s form the C1 complex. Antibodies of the adaptive immune system can bind antigen, forming an antigen-antibody complex. When C1q binds antigen-antibody complexes, the C1 complex becomes activated. Activation of the C1 complex initiates the classical complement pathway of the complement system.\n\u003cbr\u003e \n\u003cbr\u003e C1q nephropathy is a rare glomerular disease with characteristic mesangial C1q deposition noted on IHC or IF microscopy. It is histologically defined and poorly understood. Light microscopic features are heterogeneous and comprise minimal change disease (MCD), focal segmental glomerulosclerosis (FSGS), and proliferative glomerulonephritis. Clinical presentation is also diverse, and ranges from asymptomatic hematuria or proteinuria to frank nephritic or nephrotic syndrome in both children and adults. Hypertension and renal insufficiency at the time of diagnosis are common findings. Lupus nephritis is an inflammation of the kidneys caused by Systemic Lupus Erythematosus. Immunofluorescence reveals positively for IgG, IgA, IgM, C3, and C1q.\u003c\/p\u003e","brand":"biosb","offers":[{"title":"BSB 3019,3.0 mL,Tinto Predilute","offer_id":49735324270832,"sku":"BSB 3019","price":289.0,"currency_code":"USD","in_stock":true},{"title":"BSB 3020,7.0 mL,Tinto Predilute","offer_id":49735324303600,"sku":"BSB 3020","price":522.0,"currency_code":"USD","in_stock":true},{"title":"BSB 3021,15.0 mL,Tinto Predilute","offer_id":49735324336368,"sku":"BSB 3021","price":941.0,"currency_code":"USD","in_stock":true},{"title":"BSB 3022,0.1 mL,Concentrate","offer_id":49735324369136,"sku":"BSB 3022","price":183.0,"currency_code":"USD","in_stock":true},{"title":"BSB 3023,0.5 mL,Concentrate","offer_id":49735324401904,"sku":"BSB 3023","price":445.0,"currency_code":"USD","in_stock":true},{"title":"BSB 3024,1.0 mL,Concentrate","offer_id":49735324434672,"sku":"BSB 3024","price":867.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0686\/3660\/6704\/files\/PI3024.jpg?v=1778685348"}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0686\/3660\/6704\/collections\/1_SARS-CoV-2-Infected-Testis-1024x785.jpg?v=1708317401","url":"https:\/\/www.biosb.com\/collections\/antibodies.oembed","provider":"Biosb","version":"1.0","type":"link"}