tnfa-ip2 tnfa ip2 tnfaip2 tnfa anti-tnfa antibody immunohistochemistry ihc

TNFa-IP2 Antibody Immunohistochemistry on a FFPE SARS-CoV-2 Infected Lung Tissue

Specification Sheets
Safety Data Sheet

SDS

Intended Use For In Vitro Diagnostic Use
Summary and Explanation

Tumor Necrosis Factor alpha Induced-Protein 2 (also known as B94) is a 73‐kDa polypeptide involved in pathways of inflammation, metastasis, tumor vasculature, and angiogenesis. The protein has an exocyst complex, Dsl1 complex, conserved oligomeric Golgi (COG) complex and the Golgi‐associated retrograde protein (GARP) complex. 

TNFa-IP2 antibody expression is found in epithelial cells, and immune cells exposed to Tumor Necrosis Factor alpha (TNFa), IL-1beta, LPS, interferon-y, Retinoic Acid, Latent Membrane Protein 1 (LMP1), and other pro-inflammatory cytokines.  TNFaIP can inhibit NFKB to further reduce inflammation in renal dysfunction and septic shock. and can interact with GTPases to regulate breast cancer and HeLa cell actin cytoskeleton and cell structure. TNFaIP2 also participates in T-cell migration as an inflammatory regulator of chemokine secretion, and promotes metastasis and microvessel formation in nasopharyngeal carcinoma.

Antibody Type Mouse Monoclonal Clone BSB-141
Isotype IgG1 Reactivity Paraffin, Frozen
Localization Cytoplasmic, Membranous Control Testis, Tonsil, Lung, Kidney
Presentation TNFa-IP2 is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Availability
Catalog No. Antibody Type Dilution Volume/QTY
BSB-3708-3 Prediluted Ready-To-Use 3.0 ml
BSB-3708-7 Prediluted Ready-To-Use 7.0 ml
BSB-3708-15 Prediluted Ready-To-Use 15.0 ml
BSB-3708-01 Concentrated 1:50-1:200 0.1 ml
BSB-3708-05 Concentrated 1:50-1:200 0.5 ml
BSB-3708-1 Concentrated 1:50-1:200 1.0 ml
BSB-3708-CS Control Slides 5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.
Synonyms: tnfaip2, tnfa, tnfaip, tnfa-ip2, anti-tnfa-ip2, anti-tnfaip2 anti-tnfa, anti-tnfaip, Tumor Necrosis Factor alpha Induced-Protein 2, anti-B94, b94 antibody, cytokine storm, cytokine storm syndrome, cytokine storm antibody, cytokine storm antibodies, sars-cov-2 receptors, sars cov-2 receptors, covid-19 receptors, sars-cov-2 antibodies sars-cov-2 ihc, sars-cov-2 immunohistochemistry
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