IHC of TCR Alpha on an FFPE Lung Adenocarcinoma Tissue

Specification Sheets
Safety Data Sheet

SDS

Intended Use For In Vitro Diagnostic Use
Summary and Explanation T-cell receptor alpha locus is a protein that in humans is encoded by the TRA gene, also known as TCRA or TRAα; It contributes the alpha chain to the larger TCR protein (T-cell receptor). The T cell receptor or TCR is a molecule found on the surface of T lymphocytes (or T cells) that is responsible for recognizing antigens bound to major histocompatibility complex (MHC) molecules. The TCR is composed of two different protein chains (that is, it is a heterodimer). In 95% of T cells, this consists of an alpha (α) and beta (β) chain, whereas in 5% of T cells this consists of gamma and delta (γ/δ) chains. This ratio changes during ontogeny and in cancers, such as Leukemia.
Antibody Type Mouse Monoclonal Clone BSB-126
Isotype IgG2a/K Reactivity Paraffin, Frozen
Localization Cytoplasmic, Membranous Control Thymus, Tonsil, Lymph Node, Spleen, Hodgkin’s Lymphoma & BDCM & CCRF-CEM Cell Lines
Presentation TCR Alpha is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Availability
Catalog No. Antibody Type Dilution Volume/QTY
BSB 3637 Prediluted Ready-To-Use 3.0 ml
BSB 3638 Prediluted Ready-To-Use 7.0 ml
BSB 3639 Prediluted Ready-To-Use 15.0 ml
BSB 3640 Concentrated 1:25-1:100 0.1 ml
BSB 3641 Concentrated 1:25-1:100 0.5 ml
BSB 3642 Concentrated 1:25-1:100 1.0 ml
BSB 3643 Control Slides 5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.