IHC of p16 on an FFPE Mucoepidermoid Carcinoma Tissue
|Intended Use||For In Vitro Diagnostic Use|
|Summary and Explanation||p16 is a tumour supporessor gene. p16 is an important gene in regulating the cell cycle. p16INK4a regulates the cell cycle by binding and deactivating various cyclin-CdK complexes. p16 is a G1/S-cell cycle regulator that is involved in the pathway that converges in the tumor suppressor protein Rb.|
|Antibody Type||Mouse Monoclonal||Clone||16P04, JC2|
|Localization||Cytoplasmic, Nuclear||Control||Testis, NSCLC, TCC|
|Presentation||Anti-p16 is a mouse monoclonal antibody derived from cell culture supernantant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, contain-
ing BSA and sodium azide as a preservative.
|Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.|