IHC of CD61 on an FFPE Kidney Tissue
|Intended Use||For In Vitro Diagnostic Use|
|Summary and Explanation||CD61 is a glycoprotein found on megakaryocytes (bone marrow cells), platelets and their precursors. CD61 antigen plays a role in platelet aggregation and also as a receptor for fibrinogen, fibronectin, von Willebrand factor and vitronectin.
CD61 labels the IIIa subunit of the noncovalently-linked glycoprotein heterodimer IIb/IIIa complex present on human platelets and their precursors. This antibody is useful in identifying megakaryoblastic differentiation as seen in Megakaryoblastic Leukemia.
|Antibody Type||Rabbit Monoclonal||Clone||EP65|
|Localization||Cytoplasmic||Control||Brain, Kidney, Testes, Bone Marrow|
|Presentation||CD61 is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.|
|Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.|