cd57 anti-cd57 nk-1 nk1 nk 1 anti-nk-1 anti-nk1 anti-nk 1 antibody immunohistochemistry ihc

CD57 Antibody Immunohistochemistry on an FFPE Tonsil Tissue

Specification Sheets
Safety Data Sheet
Intended UseFor In Vitro Diagnostic Use
Summary and Explanation

CD57 (NK-1) recognizes an oligosaccharide (MW 100-110 kDa) antigenic determinant on myeloid cells and on a variety of polypeptides, lipids and chondroitan sulfate proteoglycans. This surface antigen is associated with myelin-associated glycoprotein (MAG). The CD57 antigen is present on 15-20% of normal peripheral blood mononuclear cells. It is expressed on a subset of natural killer cells (60%) and on a subset of T-lymphocytes. This carbohydrate is also present on N-CAM in the nervous system.

Follicular Center-cell Lymphomas often contain many NK cells within the neoplastic follicles. CD57 antibody (NK-1) reportedly also reacts with a variety of cell types in non-lymphoid tissues. CD57 antibody stains neuroendocrine cells and their tumors, including Carcinoid Tumor and Medulloblastomas. CD57 also reacts with a variety of cell types in non-lymphoid tissues, including Neurofibroma, Ganglioneuroma, and Prostate Carcinoma.

Antibody TypeMouse MonoclonalCloneBSB-10 (CD57/B8)
IsotypeIgM/KReactivityParaffin, Frozen
LocalizationMembranousControlTonsil, Lymph Node
PresentationCD57 is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Availability
Catalog No.Antibody TypeDilutionVolume/QTY
BSB 5274PredilutedReady-To-Use3.0 ml
BSB 5275PredilutedReady-To-Use7.0 ml
BSB 5276PredilutedReady-To-Use15.0 ml
BSB 5277Concentrated1:100-1:5000.1 ml
BSB 5278Concentrated1:100-1:5000.5 ml
BSB 5279Concentrated1:100-1:5001.0 ml
BSB 5280Control Slides5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.
Synonyms: B3GAT1, anti-cd57, anti cd57, Beta 1 3 glucuronyltransferase 1, beta 1 3 glucuronyltransferase 1 glucuronosyltransferase P, CD57, CD57 antigen, Galactosylgalactosylxylosylprotein 3 beta glucuronosyltransferase 1, GlcAT P, GLCATP, GlcUAT P, Glucuronosyltransferase P, HNK 1, HNK1, LEU7, LEU7 antigen, NK 1, UDP GlcUA glycoprotein beta 1 3 glucuronyltransferase, GLCUATP, NK1, anti-nk1, anti nk1