cd56 anti-cd56 antibody immunohistochemistry ihc

CD56 Antibody Immunohistochemistry on an FFPE Neuroblastoma Tissue

Specification Sheets
Safety Data Sheet
Intended UseFor In Vitro Diagnostic Use
Summary and Explanation

CD56 or Neural-Cell Adhesion Molecule (NCAM) is a homophilic binding glycoprotein expressed on the surface of neurons, glia and skeletal muscle. CD56 has been implicated in cell-cell adhesion, neurite outgrowth, synaptic plasticity, and learning and memory.

Normal cells that stain positively for CD56 antibody include NK cells, activated T-cells, brain and cerebellum, and neuroendocrine tissues. Tumors that are CD56 positive are Myeloma, Myeloid Leukemia, Neuroendocrine tumors, Wilm’s Tumor, Adult Neuroblastoma, NK/T cell Lymphomas, Pancreatic Acinar-cell Carcinoma, Pheochromocytoma, and Small-cell Lung Carcinoma. It is also expressed on some mesodermally-derived tumors (Rhabdomyosarcoma). Ewing’s Sarcoma/PNET is CD56 negative.

Antibody TypeMouse MonoclonalClone123C3.D5
IsotypeIgG1/KReactivityParaffin, Frozen
LocalizationMembranousControlPancreas, Tonsil, Neuroblastoma, Brain, Thyroid, Prostate, Colon, Lung SCC
PresentationCD56 is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Availability
Catalog No.Antibody TypeDilutionVolume/QTY
BSB 5267PredilutedReady-To-Use3.0 ml
BSB 5268PredilutedReady-To-Use7.0 ml
BSB 5269PredilutedReady-To-Use15.0 ml
BSB 5270Concentrated1:250-1:10000.1 ml
BSB 5271Concentrated1:250-1:10000.5 ml
BSB 5272Concentrated1:250-1:10001.0 ml
BSB 5273Control Slides5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.
Synonyms: CD56, NCAM1, Neural cell adhesion molecule 1, anti-NCAM, anti NCAM, anti-NCAM1, anti NCAM1, anti-CD56, anti CD56, anti-neural cell adhesion molecule 1, anti neural cell adhesion molecule 1, antigen recognized by monoclonal antibody 5 1H11, MSK39, N CAM 1, NCAM, NCAM 1, neural cell adhesion molecule NCAM