CD45 RA anti-cd45ra antibody immunohistochemistry ihc

CD45RA Antibody Immunohistochemistry on an FFPE Tonsil Tissue

Specification Sheets
Safety Data Sheet
Intended UseFor In Vitro Diagnostic Use
Summary and Explanation

CD45 is a complex molecule and is comprised of different glycoproteins ranging from 180-240 kDa. Expression of CD45 is found on all hemopoietic cells. Detection of the different isoforms can distinguish between different cell forms (e.g., naive T-cells and memory T-cells). CD45RA is an isoform of the CD45 complex and has restricted expression between different subtypes of lymphoid cells.

CD45RA antibody reacts with mature, non-activated T and B-cells. CD45RA is also reactive with medullary thymocytes, mantle-zone lymphocytes in follicles of lymph nodes, spleen and lymphocytes of the paracortex. CD45RA antibody shows no reactivity with cortical thymocytes, immature T-cells or activated B-cells in germinal centers.

Antibody TypeMouse MonoclonalClone4KB5
IsotypeIgG1/KReactivityParaffin, Frozen
LocalizationMembranousControlTonsil, Lymph Node
PresentationCD45RA is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Availability
Catalog No.Antibody TypeDilutionVolume/QTY
BSB 5253Tinto PredilutedReady-To-Use3.0 ml
BSB 5254Tinto PredilutedReady-To-Use7.0 ml
BSB 5255Tinto PredilutedReady-To-Use15.0 ml
BSB 5256Concentrated1:25-1:1000.1 ml
BSB 5257Concentrated1:25-1:1000.5 ml
BSB 5258Concentrated1:25-1:1001.0 ml
BSB 5259Control Slides5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.
Synonyms: CD45, protein tyrosine phosphatase receptor type C, PTPRC, sc20057, sc-20057, 20057, anti-CD45RA, anti CD45RA, anti-PTPRC, anti PTPRC, anti-CD45, anti CD45, anti-protein tyrosine phosphatase receptor type C, anti protein tyrosine phosphatase receptor type C, B220, CD45 antigen, CD45R, glycoprotein, GP180, L CA, LCA, Leukocyte common antigen, LY5, protein tyrosine phosphatase receptor type c polypeptide, T200, T200 glycoprotein, T200 leukocyte common antigen, Lymphocyte, 5 Ly 5, Ly 5, Lyt 4, loc, receptor type tyrosine protein phosphatase C