cd20 anti-cd20 antibody immunohistochemistry ihc

CD20 Antibody Immunohistochemistry on an FFPE Colon Tissue

Specification Sheets
Safety Data Sheet
Intended UseFor In Vitro Diagnostic Use
Summary and Explanation

CD20 is a transmembrane, non-glycosylated protein expressed on B-cell precursors and mature B-cells, but lost following differentiation into plasma cells. This antibody does not cross-react with non-hematopoietic neoplasms. CD20 (B-cell Pan) reacts with a membrane antigen present in B-cells.

CD20 antibody strongly recognizes Reed-Sternberg cells predominant in Hodgkin’s disease. Since no staining of histiocytes or plasma cells has been observed and CD20 antibody has not been detected in T-cell malignancies, it is a very strong marker of B-cell Lymphomas. B-cell Panmarker recognizes a formalin-resistant intracytoplasmic antigen.

Antibody TypeMouse MonoclonalCloneL26
IsotypeIgG2a/KReactivityParaffin, Frozen
LocalizationMembranousControlTonsil, Lymph Node
PresentationCD20 is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Availability
Catalog No.Antibody TypeDilutionVolume/QTY
BSB 5190PredilutedReady-To-Use3.0 ml
BSB 5191PredilutedReady-To-Use7.0 ml
BSB 5192PredilutedReady-To-Use15.0 ml
BSB 5193Concentrated1:250-1:10000.1 ml
BSB 5194Concentrated1:250-1:10000.5 ml
BSB 5195Concentrated1:250-1:10001.0 ml
BSB 5196Control Slides5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.
Synonyms: S4A1, anti-CD20, anti CD20, B-lymphocyte antigen CD20, Leukocyte surface antigen Leu-16, anti-MS4A1, anti MS4A1, anti-B-lymphocyte antigen CD20, anti B-lymphocyte antigen CD20, anti-Leukocyte surface antigen Leu-16, anti Leukocyte surface antigen Leu-16, membrane spanning 4 domains subfamily A member 1, B1, Bp35, CD20, CVID5, LEU 16, MS4A2, S7