Immunohistochemistry or Immunocytochemistry is the name of the method for localizing specific antigens in tissue or cells using antibodies, enzyme conjugates and substrate-chromogens. The antigen-antibody reaction can be evidenced with an optical microscope. The antibodies can be polyclonal or monoclonal (usually from mouse or rabbit) in origin. These non-infectious biological reagents are used by research and clinical laboratories to detect the presence of infectious agents, cancer and other proteins of interest.
Bio SB offers a wide range of rabbit and mouse antibodies for RUO (Research Use only; BIO SB line) or for IVD (In Vitro Diagnostics, Cell Marque line) as well as complete detection systems or its components. We offer both HRP and AP 3-step ImmunoDetector and 2-step, non-Biotin PolyDetector Systems that allow for the demonstration of antigens in paraffin-embedded tissue, cryostat sections, cytosmears, and cell preparations.
The ImmunoDetector kits use the traditional 3-step Biotin-Streptavidin-Enzyme / Substrate-Chromogen technology while the PolyDetector kits have been developed using a proprietary tandem hyperlabelling technology used to directly label immunoglobulins with enzymes. This ensures consistent and reproducible immunostaining for all types of nuclear, cytoplasmic and membranal antigens, in different types of tissues or cells.
Bio SB Products
Cell Marque Products