IHC of WT1 on an FFPE Testicular Cancer Tissue

IHC of WT1 on a FFPE Testicular Cancer Tissue

Specification Sheets
Safety Data Sheet

SDS

Intended Use For In Vitro Diagnostic Use
Summary and Explanation Wilms’ Tumor Protein (WT1) is a suppressor gene located on Chromosome 11p13. Mutations of the WT1 gene on Chromosome 11 are observed in approximately 20% of Wilms tumors. At least half of the Wilms tumors with mutations in WT1 also carry mutations in CTNNB1, the gene encoding the proto-oncogene beta-catenin.
Wilms’ tumor is a neoplasm of the kidneys that typically occurs in children. It is also known as a Nephroblastoma. WT1 has been identified in proliferative mesothelial cells, Malignant Mesothelioma, Ovarian Cystadenocarcinoma,
Gonadoblastoma, Nephroblastoma and Desmoplastic Small Round Cell Tumor. Lung Adenocarcinomas rarely stain positive with this antibody.
Antibody Type Mouse Monoclonal Clone 6F-H2
Isotype IgG1/K Reactivity Paraffin, Frozen
Localization Nuclear Control Testicle, Fallopian Tube, Kidney, Malignant Mesothelioma
Presentation WT1 is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Availability
Catalog No. Antibody Type Dilution Volume/QTY
BSB 6029 Prediluted Ready-To-Use 3.0 ml
BSB 6030 Prediluted Ready-To-Use 7.0 ml
BSB 6031 Prediluted Ready-To-Use 15.0 ml
BSB 6032 Concentrated 1:100-1:500 0.1 ml
BSB 6033 Concentrated 1:100-1:500 0.5 ml
BSB 6034 Concentrated 1:100-1:500 1.0 ml
BSB 6035 Control Slides 5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.
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