IHC of Villin on an FFPE Colon Tissue

IHC of Villin on an FFPE Colon Tissue

Specification Sheets
Safety Data Sheet

SDS

Intended Use For In Vitro Diagnostic Use
Summary and Explanation Villin is an actin-binding protein that contains gelsolin domains capped by a ”headpiece” consisting of a fast and independently-folding three-helix bundle stabilized by hydrophobic interactions. The headpiece domain is a commonly-studied protein in molecular dynamics due to its fast-folding kinetics and short primary sequence. It is a regulator of the actin cytoskeleton and is expressed mainly in the brush border in animals.
Anti-Villin labels the brush border area in the gastrointestinal mucosal epithelium. This antibody has been useful in differentiating Gastrointestinal Adenocarcinoma, Neuroendocrine Carcinomas and Ovarian Adenocarcinomas from Adenocarcinomas of other organs. Also labeled by this antibody are Merkel cells of the skin.
Antibody Type Mouse Monoclonal Clone CWWB1
Isotype IgG1 Reactivity Paraffin, Frozen
Localization Cytoplasmic Membranous Control Kidney, Colon, Small Bowel Mucosa, Colonic Mucosa
Presentation Anti-Villin is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Availability
Catalog No. Antibody Type Dilution Volume/QTY
BSB 6015 Prediluted Ready-To-Use 3.0 ml
BSB 6016 Prediluted Ready-To-Use 7.0 ml
BSB 6017 Prediluted Ready-To-Use 15.0 ml
BSB 6018 Concentrated 1:25-1:100 0.1 ml
BSB 6019 Concentrated 1:25-1:100 0.5 ml
BSB 6020 Concentrated 1:25-1:100 1.0 ml
BSB 6021 Control Slides 5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.
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