IHC of Villin on an FFPE Colon Tissue

Specification Sheets
Safety Data Sheet

SDS

Intended Use For In Vitro Diagnostic Use
Summary and Explanation Villin is an actin-binding protein that contains gelsolin domains capped by a ”headpiece” consisting of a fast and independently-folding three-helix bundle stabilized by hydrophobic interactions. The headpiece domain is a commonly-studied protein in molecular dynamics due to its fast-folding kinetics and short primary sequence. It is a regulator of the actin cytoskeleton and is expressed mainly in the brush border of the GI mucosal epithelium in animals.

Anti-Villin labels the brush border area in the gastrointestinal mucosal epithelium. This antibody has been useful in differentiating Gastrointestinal Adenocarcinoma, Neuroendocrine Carcinomas and Ovarian Adenocarcinomas from Adenocarcinomas of other organs. Also labeled by this antibody are Merkel cells of the skin.

Antibody Type Rabbit Monoclonal Clone EP 163
Isotype IgG Reactivity Paraffin, Frozen
Localization Cytoplasmic, Membranous Control Kidney, Colon, Small Bowel Mucosa, Colonic Mucosa
Presentation Villin is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Availability
Catalog No. Antibody Type Dilution Volume/QTY
BSB 2300 Prediluted Ready-To-Use 3.0 ml
BSB 2301 Prediluted Ready-To-Use 7.0 ml
BSB 2302 Prediluted Ready-To-Use 15.0 ml
BSB 2303 Concentrated 1:100-1:500 0.1 ml
BSB 2304 Concentrated 1:100-1:500 0.5 ml
BSB 2305 Concentrated 1:100-1:500 1.0 ml
BSB 2306 Control Slides 5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.
Related Products