IHC of TCR Beta on an FFPE Thymus Tissue

Specification Sheets
Safety Data Sheet

SDS

Intended Use For In Vitro Diagnostic Use
Summary and Explanation The T cell receptor or TCR is a molecule found on the surface of T lymphocytes (or T cells) that is responsible for recognizing antigens bound to major histocompatibility complex (MHC) molecules. The TCR is composed of two different protein chains (that is, it is a heterodimer). In 95% of T cells, this consists of an alpha (α) and beta (β) chain, whereas in 5% of T cells this consists of gamma and delta (γ/δ) chains. TCR Beta is a member of the immunoglobin super family and a component of the CD3/TCR complex (along with TCR Alpha).
TCR Beta is expressed by thymocytes and a majority of peripheral (α-β TCR-bearing) T-cells. TCR recognition of self-peptides has been linked to autoimmune disease. Mutant self-peptides have been associated with tumors.
Antibody Type Mouse Monoclonal Clone BSB-117
Isotype IgG1/K Reactivity Paraffin, Frozen
Localization Cytoplasmic, Membranous Control Tonsil, Lymph Node
Presentation TCR Beta is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Availability
Catalog No. Antibody Type Dilution Volume/QTY
BSB 2258 Prediluted Ready-To-Use 3.0 ml
BSB 2259 Prediluted Ready-To-Use 7.0 ml
BSB 2260 Prediluted Ready-To-Use 15.0 ml
BSB 2261 Concentrated 1:25-1:100 0.1 ml
BSB 2262 Concentrated 1:25-1:100 0.5 ml
BSB 2263 Concentrated 1:25-1:100 1.0 ml
BSB 2264 Control Slides 5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.
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