IHC of Spectrin on an FFPE Bone Marrow Tissue

IHC of Spectrin on an FFPE Bone Marrow Tissue

Specification Sheets
Safety Data Sheet

SDS

Intended Use For In Vitro Diagnostic Use
Summary and Explanation Spectrin is a cytoskeletal protein that lines the intracellular side of the plasma membrane of many cell types in pentagonal or hexagonal arrangements, forming scaffolds and playing an important role in maintenance of plasma- membrane integrity and cytoskeletal structure. The hexagonal arrangements are formed by tetramers of spectrin associating with short actin filaments at either end of the tetramer. These short actin filaments act as junctional complexes, allowing the formation of the hexagonal mesh. Spectrin is found in the intracellular side of the plasma membrane of many cell types found in muscles, red blood cells and red cell precursors. Anti-Spectrin antibody is useful in the diagnosis of Erythroid Leukemias.
Antibody Type Mouse Monoclonal Clone RBC2/3D5
Isotype IgG2b/K Reactivity Paraffin, Frozen
Localization Membranous Control Bone Marrow, Spleen
Presentation Anti-Spectrin is a Mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Availability
Catalog No. Antibody Type Dilution Volume/QTY
BSB 5938 Prediluted Ready-To-Use 3.0 ml
BSB 5939 Prediluted Ready-To-Use 7.0 ml
BSB 5940 Prediluted Ready-To-Use 15.0 ml
BSB 5941 Concentrated 1:25-1:100 0.1 ml
BSB 5942 Concentrated 1:25-1:100 0.5 ml
BSB 5943 Concentrated 1:25-1:100 1.0 ml
BSB 5944 Control Slides 5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.
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