IHC of Spectrin on an FFPE Fallopian Tube Tissue

IHC of Spectrin on an FFPE Fallopian Tube Tissue

Specification Sheets
Safety Data Sheet

SDS

Intended Use For In Vitro Diagnostic Use.
Summary and Explanation
Spectrin is a cytoskeletal protein that lines the intracellular side of the plasma membrane of many cell types in pentagonal or hexagonal arrangements, forming scaffolds and playing an important role in maintenance of plasma- membrane integrity and cytoskeletal structure. The hexagonal arrangements are formed by tetramers of spectrin associating with short actin filaments at either end of the tetramer. These short actin filaments act as junctional complexes, allowing the formation of the hexagonal mesh.
Spectrin is found in the intracellular side of the plasma membrane of many cell types found in muscles, red blood cells and red cell precursors. Anti-Spectrin antibody is useful in the diagnosis of Erythroid Leukemias and it may be a superior marker to  Glycophorin for the identification of erythroid precursors.
Antibody Type Rabbitt Monoclonal Clone EP 251
Isotype IgG Reactivity Paraffin, Frozen
Localization Membranous Control
Bone Marrow, Spleen
Presentation Spectrin is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Availability
Catalog No. Antibody Type Dilution Volume/QTY
BSB 2587 Prediluted Ready-To-Use 3.0 ml
BSB 2588 Prediluted Ready-To-Use 7.0 ml
BSB 2589 Prediluted Ready-To-Use 15.0 ml
BSB 2590 Concentrated 1:50-1:200 0.1 ml
BSB 2591 Concentrated 1:50-1:200 0.5 ml
BSB 2592 Concentrated 1:50-1:200 1.0 ml
BSB 2593 Control Slides 5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.
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