IHC of SOX-11 on an FFPE Mantle Cell Lymphoma Tissue

IHC of SOX-11 on an FFPE Mantle Cell Lymphoma Tissue

Specification Sheets
Safety Data Sheet

SDS

Intended Use For In Vitro Diagnostic Use
Summary and Explanation Transcription factor SOX-11 is a member of the group C SOX (SRY-related HMG-box) transcription factor family involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. The protein may function in the developing nervous system and play a role in tumorigenesis and adult neurogenesis. SOX-11 is normally expressed in the developing human central nervous system, Medulloblastoma, and Glioma.
Anti-SOX-11 nuclear protein expression is highly associated with both Cyclin D1-positive and negative Mantle Cell Lymphomas, with a stronger and more homogeneous Immunohistochemistry staining than Cyclin D1.
Antibody Type Mouse Monoclonal Clone CL0142
Isotype IgG2a Reactivity Paraffin, Frozen
Localization Nuclear Control Mantle Cell Lymphoma
Presentation SOX-11 is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Availability
Catalog No. Antibody Type Dilution Volume/QTY
BSB 2216 Prediluted Ready-To-Use 3.0 ml
BSB 2217 Prediluted Ready-To-Use 7.0 ml
BSB 2218 Prediluted Ready-To-Use 15.0 ml
BSB 2219 Concentrated 1:25-1:100 0.1 ml
BSB 2220 Concentrated 1:25-1:100 0.5 ml
BSB 2221 Concentrated 1:25-1:100 1.0 ml
BSB 2222 Control Slides 5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.
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