IHC of Somatostatin on an FFPE Pancreas Tissue

IHC of Somatostatin on an FFPE Pancreas Tissue

Specification Sheets
Safety Data Sheet

SDS

Intended Use For In Vitro Diagnostic Use
Summary and Explanation Somatostatin is a peptide hormone that regulates the endocrine system and affects neurotransmission and cell proliferation via interaction with G-protein-coupled somatostatin receptors and by inhibition of the release of numerous secondary hormones. Somatostatin has two active forms produced by alternative cleavage of a single preproprotein: one of 14 amino acids; the other of 28 amino acids. Somatostatin is secreted not only by cells of the hypothalamus but also by the stomach, intestine, and delta cells of the pancreas. It binds to somatostatin receptors. Somatostatin is a useful marker of D-cells of pancreatic islet cells. D-cells are used to identify hyperplasia of the pancreatic islets. Most of these tumors are malignant, giving rise to Somatostatinomas. Somatostatin suppresses gastric acid secretion, gallbladder contractions and pancreatic enzyme secretion.
Antibody Type Rabbit Polyclonal Clone N/A
Isotype IgG Reactivity Paraffin, Frozen
Localization Cytoplasmic Control Pancreas
Presentation Somatostatin antibody is the purified immunoglobulin fraction of rabbit antiserum, diluted in Phosphate Buffered Saline, pH 7.6, with protein base, and preserved with Sodium Azide preservative.
Availability
Catalog No. Antibody Type Dilution Volume/QTY
BSB 5931 Prediluted Ready-To-Use 3.0 ml
BSB 5932 Prediluted Ready-To-Use 7.0 ml
BSB 5933 Prediluted Ready-To-Use 15.0 ml
BSB 5934 Concentrated 1:100-1:500 0.1 ml
BSB 5935 Concentrated 1:100-1:500 0.5 ml
BSB 5936 Concentrated 1:100-1:500 1.0 ml
BSB 5937 Control Slides 5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.
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