IHC of Somatostatin on an FFPE Pancreas Tissue

Specification Sheets
Safety Data Sheet

SDS

Intended Use For In Vitro Diagnostic Use
Summary and Explanation Somatostatin is a peptide hormone that regulates the endocrine system and affects neurotransmission and cell proliferation via interaction with G-protein-coupled somatostatin receptors and by inhibition of the release of numerous secondary hormones. Somatostatin has two active forms produced by alternative cleavage of a single preproprotein: one of 14 amino acids; the other of 28 amino acids. Somatostatin is secreted not only by cells of the hypothalamus but also by the stomach, intestine, and delta cells of the pancreas. It binds to somatostatin receptors.
Somatostatin is a useful marker of D-cells of pancreatic islet cells. D-cells are used to identify hyperplasia of the pancreatic islets. Most of these tumors are malignant, giving rise to Somatostatinomas. Somatostatin suppresses gastric acid secretion, gallbladder contractions and pancreatic enzyme secretion.
Antibody Type Rabbit Monoclonal Clone EP130
Isotype IgG Reactivity Paraffin, Frozen
Localization Cytoplasmic Control Pancreas, Brain, Pituitary
Presentation Somatostatin is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Availability
Catalog No. Antibody Type Dilution Volume/QTY
BSB 2196 Prediluted Ready-To-Use 3.0 ml
BSB 2197 Prediluted Ready-To-Use 7.0 ml
BSB 2198 Prediluted Ready-To-Use 15.0 ml
BSB 2199 Concentrated 1:250-1:1000 0.1 ml
BSB 2200 Concentrated 1:250-1:1000 0.5 ml
BSB 2201 Concentrated 1:250-1:1000 1.0 ml
BSB 5937 Control Slides 5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.
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