IHC of Podoplanin/D2-40 on an FFPE Tonsil Tissue

IHC of Podoplanin / D2-40 on an FFPE Tonsil Tissue

Specification Sheets
Safety Data Sheet

SDS

Intended Use For In Vitro Diagnostic Use
Summary and Explanation Podoplanin is a transmembrane mucoprotein (38 kDa) recognized by the D2-40 monoclonal antibody. Podoplanin is specifically expressed in the endothelium of lymphatic capillaries but not in the blood vasculature. In normal skin and kidney, podoplanin is co-localized with VEGFR3/FLT4, another marker for lymphatic endothelial cells. Podoplanin is selectively expressed in lymphatic endothelium as well as Lymphangiomas, Kaposi’s Sarcomas and in subset Angiosarcomas with probable lymphatic differentiation. Podoplanin has also been shown to be expressed in Epithelioid Mesotheliomas, Hemangioblastomas and Seminomas.
Antibody Type Mouse Monoclonal Clone D2-40
Isotype IgG1 Reactivity Paraffin, Frozen
Localization Cytoplasmic Control Tonsil, Lymph Node, Lymphangioma
Presentation Anti-Podoplanin/D2-40 is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a
preservative.
Availability
Catalog No. Antibody Type Dilution Volume/QTY
BSB 6064 Prediluted Ready-To-Use 3.0 ml
BSB 6065 Prediluted Ready-To-Use 7.0 ml
BSB 6066 Prediluted Ready-To-Use 15.0 ml
BSB 6067 Concentrated 1:100-1:500 0.1 ml
BSB 6068 Concentrated 1:100-1:500 0.5 ml
BSB 6069 Concentrated 1:100-1:500 1.0 ml
BSB 6070 Control Slides 5
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.
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